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All mouse models of demyelinating disease with phenotypic similarity to the human disease
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
  | multiple sclerosis | Prf1tm1Sdz/Prf1tm1Sdz | C57BL/6-Prf1tm1Sdz/J | J:120427 | View | |||
| multiple sclerosis | Tg(Tnf)6074Gkl/0 | involves: C57BL/6 * CBA | J:106592 | View | ||||
| multiple sclerosis |
Tg(Tnf)6074Gkl/0 Tnfrsf1btm1Mwm/Tnfrsf1btm1Mwm |
involves: 129S2/SvPas * C57BL/6 * CBA | J:106592 | View | ||||
| | multiple sclerosis | Lrch1em1Hwa/Lrch1em1Hwa | Not Specified | J:238772 | View | |||
| | multiple sclerosis |
H2dlAb1-Ea/H2dlAb1-Ea Tg(HLA-DRA,HLA-DRB5*0101)hiKito/0 Tg(TRATL3A6,TRBTL3A6)#Kito/0 |
involves: 129S2/SvPas * C57BL/6 | J:189816 | View | |||
| multiple sclerosis |
Igh-Jtm1Aigl/Igh-J+ Mogtm1Dpd/Mogtm1Dpd Tg(Tcra2D2,Tcrb2D2)1Kuch/0 |
involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6 | J:151335 | View | ||||
| multiple sclerosis |
Mogtm1(cre)Gkl/Mogtm1(cre)Gkl Tg(Tcra2D2,Tcrb2D2)1Kuch/0 |
C57BL/6-Mogtm1(cre)Gkl Tg(Tcra2D2,Tcrb2D2)1Kuch | J:151335 | View | ||||
| multiple sclerosis |
Mogtm1Dpd/Mogtm1Dpd Rag2tm1Cgn/Rag2tm1Cgn Tg(Tcra2D2,Tcrb2D2)1Kuch/0 |
involves: 129S2/SvPas * C57BL/6 | J:151335 | View | ||||
| multiple sclerosis |
Mogtm1Dpd/Mogtm1Dpd Tg(Tcra2D2,Tcrb2D2)1Kuch/0 |
involves: 129S2/SvPas * C57BL/6 | J:151335 | View | ||||
| multiple sclerosis |
Tg(Gfap-TNF*)K21Gkl/0 Tnfrsf1atm1Blt/Tnfrsf1a+ |
involves: 129P2/OlaHsd * C57BL/6 * CBA | J:106592 | View | ||||
| Transgenes and Other Mutations | multiple sclerosis | Tg(Gfap-TNF*)K21Gkl/0 | involves: C57BL/6 * CBA | J:106592 | View | |||
| multiple sclerosis | Tg(H2-Kb-Tcra,-Tcrb)1640Kurs/0 | SJL.FVB-Tg(H2-Kb-Tcra,-Tcrb)1640Kurs | J:149511 | View | ||||
| multiple sclerosis | Tg(Mbp-Pad2)28Fgm/0 | involves: CD-1 | J:142650 | View | ||||
| multiple sclerosis | Tg(Mbp-Pad2)28Fgm/Tg(Mbp-Pad2)28Fgm | involves: CD-1 | J:142650 | View | ||||
| multiple sclerosis | Tg(PLP1*)4Rsj/0 | involves: CD-1 | J:161344, J:171534 | View | ||||
| Additional Complex Models | multiple sclerosis |
Gt(ROSA)26Sortm1(DTA)Jpmb/Gt(ROSA)26Sor+ Tg(Plp1-cre/ERT)3Pop/0 |
involves: 129S/SvEv * C57BL/6 * DBA/2 | J:234435 | View | |||
| multiple sclerosis |
H2u/H2u Rag1tm1Mom/Rag1tm1Mom Tg(Tcra19,Tcrb19)#Stl/0 |
either: (involves: 129S7/SvEvBrd * C57BL/6 * PL/J) or (involves: 129S7/SvEvBrd * C57BL/6 * C57BL/10 * PL/J) | J:19795 | View | ||||
| multiple sclerosis |
H2u/H2u Tg(TCRA)B1Jg/? Tg(TCRB)C14Jg/? |
involves: C57BL/6 * C57BL/10SnSg * DBA/2 * PL/J | J:92991 | View | ||||
| multiple sclerosis |
Igh-Jtm1Aigl/Igh-J+ Tg(Tcra2D2,Tcrb2D2)1Kuch/0 |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 | J:151335 | View | ||||
| multiple sclerosis |
Rag2tm1.1Cgn/Rag2tm1.1Cgn Tg(HLA-DR2)#Lfug/0 Tg(TCROb.1A12)#Lfug/0 |
involves: C57BL/6 * DBA/2 | J:134764 | View | ||||
| multiple sclerosis |
Tg(Cd4-CD4)2362Litt/0 Tg(HLA-DR2)#Lfug/0 Tg(TCROb.1A12)#Lfug/0 |
involves: C57BL/6 * DBA/2 * SJL | J:134764 | View | ||||
| multiple sclerosis |
Tg(HLA-DR2)#Lfug/0 Tg(TCROb.1A12)#Lfug/0 |
involves: C57BL/6 * DBA/2 | J:134764 | View | ||||