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All mouse models of bone inflammation disease with phenotypic similarity to the human disease
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
  | osteoarthritis | Gdf5Rgsc451/Gdf5Rgsc451 | C57BL/6JJcl-Gdf5Rgsc451 | J:125122 | View | |||
| osteoarthritis | Matn3tm1Brd/Matn3tm1Brd | involves: 129S7/SvEvBrd * C57BL/6 | J:112002 | View | ||||
| rheumatoid arthritis | TnfBpsm1/Tnf+ | involves: C57BL/6 | J:226052 | View | ||||
| rheumatoid arthritis | TnfBpsm1/TnfBpsm1 | involves: C57BL/6 | J:226052 | View | ||||
| rheumatoid arthritis | Tnftm1Gkl/Tnftm2Gkl | involves: 129S/SvEv * C57BL/6 | J:54056 | View | ||||
| rheumatoid arthritis | Tnftm2Gkl/Tnf+ | involves: 129S/SvEv * C57BL/6 | J:54056 | View | ||||
| rheumatoid arthritis | Tnftm2Gkl/Tnf+ | involves: 129S/SvEv * C57BL/6J | J:264147 | View | ||||
| rheumatoid arthritis | Tnftm2Gkl/Tnftm2Gkl | involves: 129S/SvEv * C57BL/6 | J:54056 | View | ||||
| | chronic recurrent multifocal osteomyelitis | Pstpip2cmo/Pstpip2cmo | C.Cg-Pstpip2cmo/J | J:105410, J:104476 | View | |||
| osteoarthritis | Atp7aMo-blo/Y | B6.Cg-Atp7aMo-blo/J | J:36378 | View | ||||
| osteoarthritis |
Bmp7tm1.1Dgra/Bmp7tm1.1Dgra Tg(Prrx1-cre)1Cjt/0 |
involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NTac * SJL/J | J:221175 | View | ||||
| osteoarthritis |
Bmpr1atm2.1Bhr/Bmpr1atm2.2Bhr Tg(Gdf5-cre,-ALPP)1Kng/0 |
involves: 129 * C57BL/6 * FVB/N-Tg(Gdf5-cre-ALPP)1Kng | J:97780 | View | ||||
| osteoarthritis | Col9a1tm1Jae/Col9a1tm1Jae | involves: 129S2/SvPas | J:117910 | View | ||||
| osteoarthritis | Col11a1cho/Col11a1+ | involves: C57BL/6Fr | J:106282 | View | ||||
| osteoarthritis | Enpp1ttw/Enpp1ttw | involves: ICR | J:37369, J:19124 | View | ||||
| osteoarthritis |
Ergtm1.1Iwamo/Ergtm1.1Iwamo Tg(Gdf5-cre,-ALPP)1Kng/? |
involves: 129S4/SvJaeSor * C57BL/6 * FVB/N | J:243715 | View | ||||
| osteoarthritis | Errfi1tm1Gvw/Errfi1tm1Gvw | Not Specified | J:100927 | View | ||||
| osteoarthritis |
Myl3tm1a(EUCOMM)Hmgu/Myl3tm1a(EUCOMM)Hmgu Tg(Col2a1-cre)1Xya/0 |
involves: C57BL/6J * C57BL/6N | J:343166 | View | ||||
| osteoarthritis | Smad3tm1Cxd/Smad3tm1Cxd | involves: 129S6/SvEvTac | J:68792 | View | ||||
| osteoarthritis |
Tg(Col2a1-cre/ERT2)1Dic/0 Tgfbr1tm1.1Karl/Tgfbr1tm1.1Karl |
involves: 129 * C57BL/6 | J:271724 | View | ||||
| rheumatoid arthritis |
Dnase2atm1Osa/Dnase2atm1Osa Ifnar1tm1Agt/Ifnar1tm1Agt |
involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6 | J:114982, J:238323 | View | ||||
| rheumatoid arthritis |
Dnase2atm1Osa/Dnase2atm2Osa Tg(Mx1-cre)1Cgn/0 |
involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6 * CBA | J:114982 | View | ||||
| rheumatoid arthritis | Il6sttm1Thir/Il6sttm1Thir | involves: 129 * C57BL/6 | J:133059 | View | ||||
| rheumatoid arthritis | Mmp14tm1Hbh/Mmp14tm1Hbh | involves: 129P2/OlaHsd * Black Swiss | J:57969 | View | ||||
| rheumatoid arthritis | Zap70m1Saka/Zap70m1Saka | involves: BALB/c | J:86607 | View | ||||
| rheumatoid arthritis | Zfp36tm1Pjb/Zfp36tm1Pjb | B6.Cg-Zfp36tm1Pjb | J:214114 | View | ||||
| Transgenes and Other Mutations | osteoarthritis | Tg(MT2A-TGFBR2)4Rser/0 | involves: C57BL/6 * DBA | J:44579 | View | |||
| rheumatoid arthritis |
H2b/H2g7 Tg(TcraR28,TcrbR28)KRNDim/0 |
involves: C57BL/6 * NOD * SJL | J:36815 | View | ||||
| rheumatoid arthritis | Tg(CAG-SYVN1)1Tn/? | D1.Cg-Tg(CAG-SYVN1)1Tn | J:86009 | View | ||||
| rheumatoid arthritis | Tg(FCGR2A)11Mkz/Tg(FCGR2A)11Mkz | involves: C57BL/6 * SJL | J:136516 | View | ||||
| rheumatoid arthritis | Tg(HLA-DRA*0101,HLA-DRB1*0101)1Dmz/Tg(HLA-DRA*0101,HLA-DRB1*0101)1Dmz | involves: C57BL/6 * C57BL/10Sn * SJL/J | J:108635 | View | ||||
| rheumatoid arthritis | Tg(TcraR28,TcrbR28)KRNDim/0 | involves: C57BL/6 * NOD * SJL | J:36815 | View | ||||
| rheumatoid arthritis | Tg(TNF)197Gkl/0 | involves: C57BL/6 * CBA | J:92576 | View | ||||
| rheumatoid arthritis | Tg(TNF)3647Gkl/0 | involves: C57BL/6 * CBA | J:190204 | View | ||||
| Additional Complex Models | arthritis |
Tg(H2-Ea-HA)HACIIAjca/0 Tg(Tcra/Tcrb)1Vbo/0 |
C.Cg-Tg(H2-Ea-HA)HACIIAjca Tg(Tcra/Tcrb)1Vbo | J:209872 | View | |||
| arthritis |
Tg(H2-Ea-HA)HACIIAjca/0 Tg(TcraS106-1,TcrbS106-1)TS1SWAjca/0 |
C.Cg-Tg(H2-Ea-HA)HACIIAjca Tg(TcraS106-1,TcrbS106-1)TS1SWAjca | J:209872 | View | ||||
| osteoarthritis |
Bgntm1Mfy/Y Fmodtm1Aol/Fmodtm1Aol |
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ | J:112779, J:117908 | View | ||||
| rheumatoid arthritis |
H2q/? Ncf1m1J/Ncf1m1J |
B6.Cg-Ncf1m1J H2q | J:92437 | View | ||||
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No similarity to the expected human disease phenotype was found.
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
| NOT Models | rheumatoid arthritis |
Ighmtm1Cgn/Ighmtm1Cgn Tg(TcraR28,TcrbR28)KRNDim/0 |
involves: 129S2/SvPas * C57BL/6 * NOD * SJL | J:36815 | View | |||