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All mouse models of skin carcinoma with phenotypic similarity to the human disease
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Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
basal cell carcinoma |
Ptch1tm1Bjw/Ptch1tm1Bjw Tg(KRT14-cre)8Brn/0 |
involves: 129T2/SvEms * FVB/N | J:231264 | View | ||||
basal cell carcinoma |
Ptch1tm1Hahn/Ptch1tm1Hahn Gt(ROSA)26Sortm2(cre/ERT2)Brn/Gt(ROSA)26Sor+ |
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ | J:158915 | View | ||||
basal cell carcinoma | Ptch1tm1Mps/Ptch1+ | involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2J | J:58328 | View | ||||
skin squamous cell carcinoma | Tg(KRT14-Fyn*)aJsey/0 | involves: C57BL/6 * CBA * FVB/N | J:155536 | View | ||||
basal cell carcinoma |
Dicer1tm1Snj/Dicer1tm1Snj Trp53tm1Brn/Trp53+ Tg(KRT5-cre/PGR)1Der/0 |
involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6N * FVB/N * ICR | J:216813 | View | ||||
Transgenes and Other Mutations | skin squamous cell carcinoma | Tg(KRT14-HPV16)wt1Dh/0 | either: FVB.Cg-Tg(KRT14-HPV16)wt1Dh or (involves: C57BL/6 * DBA/2 * FVB/N) | J:20130 | View |
No similarity to the expected human disease phenotype was found.
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Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
NOT Models | skin squamous cell carcinoma | Tg(KRT14-HPV16)wt1Dh/0 | C.Cg-Tg(KRT14-HPV16)wt1Dh | J:20130 | View | |||
skin squamous cell carcinoma | Tg(KRT14-HPV16)wt1Dh/0 | either: (involves: C57BL/6 * DBA/2) or (involves: C57BL/6 * DBA/2 * SENCAR * SSIN) | J:20130 | View |