Excel File
Text File
All mouse models of uveal disease with phenotypic similarity to the human disease
|
||||||||
Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
aniridia | Pax6Sey-Dey/Pax6+ | C3H/HeJ-Pax6Sey-Dey | J:10820 | View | ||||
aniridia | Pax6Sey-Neu/Pax6+ | involves: 102 * C3H | J:83026 | View | ||||
choroideremia |
Chmtm1.1Seab/Chmtm1.1Seab Tg(Six3-cre)69Frty/0 |
involves: 129X1/SvJ * C57BL/6 * DBA/2 | J:105458 | View | ||||
choroideremia |
Chmtm1.1Seab/Y Tg(Six3-cre)69Frty/0 |
involves: 129X1/SvJ * C57BL/6 * DBA/2 | J:105458 | View | ||||
choroideremia | Chmtm1.2Seab/Chm+ | involves: 129X1/SvJ | J:105458 | View | ||||
choroideremia | Chmtm1.3Seab/Chm+ | involves: 129X1/SvJ | J:105458 | View | ||||
exfoliation syndrome | Loxl1tm1Tili/Loxl1tm1Tili | involves: 129S1/Sv * 129X1/SvJ * C57BL/6 | J:229298 | View | ||||
gyrate atrophy | Oatrhg/Oatrhg | B6Ei;AKR-Oatrhg/J | J:213842 | View | ||||
gyrate atrophy | Oattm1Dva/Oattm1Dva | involves: 129S7/SvEvBrd | J:60200 | View | ||||
gyrate atrophy | Oattm1Dva/Oattm1Dva | involves: 129S7/SvEvBrd * C57BL/6J | J:29269 | View | ||||
exfoliation syndrome | Lystbg-J/Lystbg-J | C57BL/6J-Lystbg-J/J | J:173521 | View | ||||
partial central choroid dystrophy | Prph2em1Sal/Prph2+ | C57BL/6J-Prph2em1Sal | J:342243 | View | ||||
partial central choroid dystrophy | Prph2em1Sal/Prph2em1Sal | C57BL/6J-Prph2em1Sal | J:342243 | View | ||||
uveal melanoma | Tg(Dct-Grm1)ESzc/0 | C57BL/6J-Tg(Dct-Grm1)ESzc | J:230115 | View | ||||
Transgenes and Other Mutations | birdshot chorioretinopathy | Tg(H2-K1-HLA-A*)28Mpla/0 | B10.Cg-Tg(H2-K1-HLA-A*)28Mpla | J:67871 | View | |||
Additional Complex Models | uveal melanoma |
Cdkn2atm1Rdp/Cdkn2a+ X/Tg(Tyr-HRAS)60Lc |
involves: 129/Sv * C57BL/6J * CBA/J * FVB/N * SJL | J:140820 | View | |||
uveal melanoma |
Gt(ROSA)26Sortm1(GNAQ*)Cvrk/Gt(ROSA)26Sor+ Tg(Mitf-cre)7114Gsb/0 |
C3FeJ.Cg-Gt(ROSA)26Sortm1(GNAQ*)Cvkr Tg(Mitf-cre)7114Gsb/Cvrk | J:225597 | View |
No similarity to the expected human disease phenotype was found.
|
||||||||
Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
NOT Models | choroideremia | Chmtm1Jvdh/Y | involves: 129P2/OlaHsd * C57BL/6 | J:40673 | View |