Excel File Text File All mouse models of skin disease with phenotypic similarity to the human disease
        Disease Term Allelic Composition Genetic Background Reference Phenotypes
      atopic dermatitis Tg(KRT5-tTA)1216Glk/0
Tg(tetO-Il13)1Tazh/0
B6.Cg-Tg(KRT5-tTA)1216Glk Tg(tetO-Il13)1Tazh J:150232 View
atopic dermatitis Tg(KRT14-Il4)#Lsch/0 involves: BALB/cBy * C57BL/6 J:126285 View
atopic dermatitis Tg(KRT14-Il18)#Knak/0 C57BL/6-Tg(KRT14-Il18)#Knak J:78602 View
autosomal recessive congenital ichthyosis 1 Tgm1tm1Kfyn/Tgm1tm1Kfyn involves: 129S1/SvImJ * 129X1/SvJ * C57BL/6 J:45653, J:74334 View
autosomal recessive congenital ichthyosis 4B Abca12el12/Abca12el12 involves: 129/Sv * C57BL/6 J:161652 View
autosomal recessive congenital ichthyosis 4B Abca12smsk/Abca12smsk involves: C57BL/6J J:262458 View
autosomal recessive congenital ichthyosis 4B Abca12tm1Lex/Abca12tm1Lex involves: 129S/SvEvBrd * C57BL/6J J:144062 View
autosomal recessive congenital ichthyosis 4B Abca12tm1Shzu/Abca12tm1Shzu B6.129S-Abca12tm1Shzu J:139048 View
autosomal recessive congenital ichthyosis 10 Pnpla1tm1a(KOMP)Wtsi/Pnpla1tm1a(KOMP)Wtsi B6NTac;B6N-Atm1Brd Pnpla1tm1a(KOMP)Wtsi/Ics J:242353 View
autosomal recessive congenital ichthyosis 13 Sdr9c7em1Maak/Sdr9c7em1Maak involves: C57BL/6J J:295441 View
basal cell carcinoma Ptch1tm1Bjw/Ptch1tm1Bjw
Tg(KRT14-cre)8Brn/0
involves: 129T2/SvEms * FVB/N J:231264 View
basal cell carcinoma Ptch1tm1Hahn/Ptch1tm1Hahn
Gt(ROSA)26Sortm2(cre/ERT2)Brn/Gt(ROSA)26Sor+
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ J:158915 View
basal cell carcinoma Ptch1tm1Mps/Ptch1+ involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2J J:58328 View
Birt-Hogg-Dube syndrome Flcntm1Baba/Flcntm1.1Lss
Tg(Cdh16-cre)91Igr/0
involves: C57BL/6 * FVB/N * ICR * SJL J:130978 View
Birt-Hogg-Dube syndrome Flcntm1Btt/Flcntm1Btt
Tg(Cdh16-cre)91Igr/0
involves: 129S4/SvJaeSor * C57BL/6 * ICR J:143922 View
Bloch-Sulzberger syndrome Ikbkgtm1Mka/Ikbkg+ involves: 129S1/Sv * 129X1/SvJ * C57BL/6J J:63054 View
Bloch-Sulzberger syndrome Ikbkgtm1Mpa/Ikbkg+ involves: C57BL/6 J:63055 View
bullous congenital ichthyosiform erythroderma Krt2Mhdadsk2/Krt2+ C3HeB/FeJ-Krt2Mhdadsk2/Ieg J:81301 View
bullous congenital ichthyosiform erythroderma Krt2Mhdadsk2/Krt2Mhdadsk2 involves: C3HeB/FeJ * C57BL/6J J:81301 View
Carvajal syndrome Dsprul/Dsprul RB156Bnr/Ei-Dsprul/GrsrJ J:217650 View
cherubism Sh3bp2tm1.1Ics/Sh3bp2tm1.1Ics involves: 129S2/SvPas * C57BL/6 J:221901 View
cherubism Sh3bp2tm1Bjro/Sh3bp2tm1Bjro involves: 129S4/SvJae * BALB/cJ * C57BL/6J J:117880 View
cutaneous porphyria Urostm1Cged/Urostm1Cged involves: 129S2/SvPas J:105776 View
cutaneous porphyria Urostm2Rjde/Urostm3Rjde involves: 129S6/SvEvTac * C57BL/6 J:132542 View
cutaneous porphyria Urostm3Rjde/Urostm3Rjde involves: 129S6/SvEvTac * C57BL/6 J:132542 View
cutis laxa Fbln5tm1Eno/Fbln5tm1Eno involves: 129S6/SvEvTac J:86754 View
cutis laxa Fbln5tm1Krc/Fbln5tm1Krc involves: 129X1/SvJ * C57BL/6 J:86753 View
dyskeratosis congenita Dkc1tm1.1Pjma/Y B6.129X1(FVB)-Dkc1tm1.1Pjma J:217050 View
dyskeratosis congenita Dkc1tm1Ppp/Dkc1+ involves: 129S1/Sv J:81054 View
dyskeratosis congenita Dkc1tm1Ppp/Y involves: 129S1/Sv J:81054 View
epidermolysis bullosa simplex Krt14tm1Der/Krt14tm1Der involves: 129X1/SvJ J:67320 View
epidermolysis bullosa simplex Krt14tm1Efu/Krt14tm1Efu involves: 129 J:25763 View
epidermolysis bullosa simplex Ogna type Plectm1Gwi/Plectm1Gwi involves: 129S1/Sv * 129X1/SvJ J:59000 View
epidermolysis bullosa simplex Ogna type Plectm2Gwi/Plectm2Gwi involves: 129S1/Sv * 129X1/SvJ J:59000 View
epidermolysis bullosa simplex Ogna type Plectm7.1Gwi/Plec+ involves: 129P2/OlaHsd * C57BL/6 J:179812 View
epidermolysis bullosa simplex Ogna type Plectm7.1Gwi/Plectm7.1Gwi involves: 129P2/OlaHsd * C57BL/6 J:179812 View
epidermolytic hyperkeratosis Krt1Mhdadsk12/Krt1+ C3HeB/FeJ-Krt1Mhdadsk12 J:108758 View
epidermolytic hyperkeratosis Krt10tm1Tmm/Krt10+ either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * BALB/c * C57BL/6) J:31853 View
epidermolytic hyperkeratosis Krt10tm1Tmm/Krt10tm1Tmm either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * BALB/c * C57BL/6) J:31853 View
erythrokeratodermia variabilis Gjb3tm2.1Kwi/Gjb3+ involves: 129P2/OlaHsd * C57BL/6 J:121802 View
isolated anhidrosis with normal sweat glands Itpr2tm1Kmik/Itpr2tm1Kmik involves: 129S4/SvJae J:217699 View
junctional epidermolysis bullosa Col17a1em1Dcr/Col17a1em1Dcr
Lamc2jeb/Lamc2jeb
B6.Cg-Lamc2jeb Col17a1em1Dcr/Dcr J:352187 View
junctional epidermolysis bullosa Col17a1em2Dcr/Col17a1em2Dcr
Lamc2jeb/Lamc2jeb
C57BL/6J-Col17a1em2Dcr/Dcr J:352187 View
junctional epidermolysis bullosa Col17a1em8Dcr/Col17a1+
Lamc2jeb/Lamc2jeb
B6.Cg-Lamc2jeb Col17a1em8Dcr/Dcr J:352187 View
junctional epidermolysis bullosa Col17a1em8Dcr/Col17a1em8Dcr C57BL/6J-Col17a1em8Dcr/DcrJ J:352187 View
junctional epidermolysis bullosa Lama3tm1Arte/Lama3tm1Arte
Tg(KRT14-cre/ERT)20Efu/0
involves: C57BL/6 * CD-1 J:240054 View
junctional epidermolysis bullosa with pyloric atresia Itgb4tm1Fgg/Itgb4tm1Fgg involves: 129S1/Sv * C57BL/6 J:48924 View
keratosis follicularis Atp2a2tm1Ges/Atp2a2+ involves: 129X1/SvJ * Black Swiss J:69754 View
Kindler syndrome Fermt1tm1Ref/Fermt1tm1Ref involves: 129S1/Sv * 129X1/SvJ J:142913 View
mal de Meleda Slurp1tm1.1Sgy/Slurp1tm1.1Sgy involves: 129 * C57BL/6 J:210836 View
mal de Meleda Slurp1tm1Lex/Slurp1tm1Lex Not Specified J:210836 View
Netherton syndrome F2rl1tm1Cgh/F2rl1tm1Cgh
Spink5tm1Hov/Spink5tm1Hov
involves: 129P2/OlaHsd * 129S4/SvJae J:180855 View
Netherton syndrome Spink5m1Btlr/Spink5m1Btlr involves: C57BL/6J J:183755 View
Netherton syndrome Spink5tm1Drh/Spink5tm1Drh involves: 129P2/OlaHsd * C57BL/6 J:95549 View
Netherton syndrome Spink5tm1Hov/Spink5tm1Hov involves: 129P2/OlaHsd * FVB J:96435 View
Netherton syndrome Spink5Tn(Pgk2-sb10,sb-Tyr)1498Ove/Spink5Tn(Pgk2-sb10,sb-Tyr)1498Ove involves: FVB/N J:93050 View
psoriasis Tg(KRT5-Stat3*A661C*N663C)1Jdg/0 involves: FVB J:95458 View
psoriasis Tg(KRT14-Vegfa)3Dtm/0 FVB/N-Tg(KRT14-Vegfa)3Dtm J:92643 View
psoriasis 2 Card14em2Tshu/Card14+ involves: C57BL/6 J:289239 View
psoriasis 2 Card14em9Lutzy/Card14+ C57BL/6J-Card14em9Lutzy/J J:262723 View
Rothmund-Thomson syndrome ApcMin/Apc+
Recql4tm1Glu/Recql4tm1Glu
involves: 129S7/SvEvBrd * C57BL/6J J:97101 View
Rothmund-Thomson syndrome Recql4tm1Abe/Recql4tm1Abe involves: 129S1/Sv * 129X1/SvJ * C57BL/6 J:85574 View
Rothmund-Thomson syndrome Recql4tm1Glu/Recql4tm1Glu involves: 129S7/SvEvBrd * C57BL/6J J:97101 View
      alopecia areata Cchcr1em1Aoka/Cchcr1em1Aoka C57BL/6NJcl-Cchcr1em1Aoka J:309941 View
atopic dermatitis Adam17tm1.2Bbl/Adam17tm1.2Bbl
Sox9tm3(cre)Crm/Sox9+
B6.129(SJL)-Sox9tm3(cre)Crm Adam17tm1.2Bbl J:229771 View
atopic dermatitis Casp8tm1Hed/Casp8tm1Hed
Tg(KRT14-cre)1Efu/0
Not Specified J:167299 View
atopic dermatitis Ctsetm1Kjy/Ctsetm1Kjy involves: C57BL/6 J:108745 View
atopic dermatitis Nfkbiatm1Stw/Nfkbiatm1Stw involves: 129S1/Sv J:32527 View
atopic dermatitis Nfkbiztm1Mamo/Nfkbiztm1Mamo involves: 129S7/SvEvBrd J:95040 View
atopic dermatitis Noa/Noa+ NOA J:43274 View
atopic dermatitis Relbtm1Brv/Relbtm1Brv either: (involves: 129S2/SvPas) or (involves: C57BL/6) or (involves: 129S2/SvPas * C57BL/6) J:63950 View
atopic dermatitis Sharpincpdm/Sharpincpdm C57BL/KaLawRij-Sharpincpdm J:14539, J:31745, J:116833 View
atopic dermatitis Tg(KRT5-rtTA)1Glk/0
Tg(tetO/CMV-Tslp)#Sfz/0
involves: C3H * C57BL/6 * FVB/N J:100506 View
atopic dermatitis Tmem79ma/Tmem79ma B6.CBACaGr-Tmem79ma/J J:202453 View
atopic dermatitis Tmem79ma/Tmem79ma involves: C57BL/6JJcl * CBA/CaGr J:202316 View
atopic dermatitis Traf3ip2adjm/Traf3ip2adjm A.KOR-Traf3ip2adjm J:162859 View
atopic dermatitis Traf3ip2adjm/Traf3ip2adjm AK.KOR-Traf3ip2adjm J:162859 View
atopic dermatitis Traf3ip2adjm/Traf3ip2adjm B6.KOR-Traf3ip2adjm J:162859 View
atopic dermatitis Traf3ip2adjm/Traf3ip2adjm C.KOR-Traf3ip2adjm J:162859 View
atopic dermatitis Traf3ip2adjm/Traf3ip2adjm KOR-Traf3ip2adjm J:162859 View
atopic dermatitis Trpv3Nh/Trpv3+ involves: DS J:42153 View
atopic dermatitis Wasltm1.1Ttha/Wasltm1.1Ttha
Tg(KRT14-cre)1Amc/0
involves: C57BL/6 * C57BL/6N * CBA J:271857 View
atopic dermatitis 2 Flgft/Flgft STOCK a/a Tmem79ma Flgft/J J:204304 View
autosomal recessive congenital ichthyosis 4B Cst6ichq/Cst6+ involves: BALB/cJ J:41426, J:90417 View
autosomal recessive congenital ichthyosis 4B Pigatm1Tak/Pigatm1Tak
Tg(KRT5-cre)1Tak/0
involves: 129S1/Sv * 129X1/SvJ * C3H * C57BL/6 J:91794 View
autosomal recessive congenital ichthyosis 4B Pigatm1Tak/Y
Tg(KRT5-cre)1Tak/0
involves: 129S1/Sv * 129X1/SvJ * C3H * C57BL/6 J:91794 View
autosomal recessive congenital ichthyosis 4B Prss8tm1.1Hum/Prss8tm1.2Hum
Tg(KRT14-cre)1Ipc/0
involves: 129/Sv * C57BL/6 * FVB/N * SJL J:100139 View
Bloch-Sulzberger syndrome NsdhlStr-1H/Nsdhl+ involves: 101/H * C3H/HeH J:106524 View
cutaneous lupus erythematosus Trex1tm1Tld/Trex1tm1Tld involves: 129P2/OlaHsd * C57BL/6J J:243357 View
cutis laxa Efemp2tm1.1Chu/Efemp2tm1.1Chu B6(SJL)-Efemp2tm1.1Chu J:223792 View
cutis laxa Ltbp4Gt(E301B04)Wrst/Ltbp4Gt(E301B04)Wrst B6N.129P2-Ltbp4Gt(E301B04)Wrst J:221200 View
dermatomyositis Tg(Krt14-Angptl2)1Yo/0 C.Cg-Tg(Krt14-Angptl2)1Yo J:181261 View
dyskeratosis congenita Tinf2tm2.2Tdl/Tinf2+ involves: BALB/cJ * C57BL/6 J:207367 View
dyskeratosis congenita Trp53tm1.1Tldo/Trp53tm1.1Tldo involves: 129S2/SvPas * BALB/c * C57BL/6 J:199308 View
epidermal appendage tumor Tg(Tff3-Tmem207)1Tamo/0 C57BL/6-Tg(Tff3-Tmem207)1Tamo J:217436 View
epidermolysis bullosa simplex Dowling-Meara type Krt5tm1Tmm/Krt5tm1Tmm involves: 129P2/OlaHsd * BALB/c J:76311 View
epidermolysis bullosa simplex Dowling-Meara type Krt14tm1Der/Krt14+
Tg(KRT5-cre/PGR)1Der/?
involves: 129X1/SvJ * FVB * ICR J:67320 View
epidermolysis bullosa simplex Dowling-Meara type Krt14tm1Der/Krt14+
Tg(KRT14-cre/PGR)1Der/?
involves: 129X1/SvJ * FVB * ICR J:67320 View
epidermolysis bullosa simplex Dowling-Meara type Krt14tm2Der/Krt14+ involves: 129X1/SvJ J:67320 View
epidermolytic hyperkeratosis Juptm1Kem/Juptm1Kem involves: 129S1/Sv * 129X1/SvJ * C57BL/6 J:38047 View
ichthyosis vulgaris Lbric-J/Lbric-J involves: 129S4/SvJae * C57BL/6 J:143838 View
junctional epidermolysis bullosa Herlitz type Itga6tm1Egl/Itga6tm1Egl either: (involves: 129S2/SvPas * C57BL/6) or (involves: 129S2/SvPas * C57BL/6 * CD-1) J:33712 View
junctional epidermolysis bullosa Herlitz type Lamb3IAP/Lamb3IAP involves: C3H * C57BL/6 J:42382 View
junctional epidermolysis bullosa Herlitz type Lamb3tm1.1Hosc/Lamb3tm1.1Hosc involves: 129S4/SvJae * C57BL/6 J:218616 View
junctional epidermolysis bullosa Herlitz type Lamc2tm1Uit/Lamc2tm1Uit involves: C57BL/6 J:85981 View
junctional epidermolysis bullosa non-Herlitz type Col17a1tm1Shzu/Col17a1tm1Shzu B6.129S-Col17a1tm1Shzu J:121695 View
junctional epidermolysis bullosa non-Herlitz type Itgb4tm1Efu/Itgb4tm1Efu involves: 129S1/Sv * 129X1/SvJ * C57BL/6 J:77644 View
junctional epidermolysis bullosa non-Herlitz type Lama3tm1Crt/Lama3tm1Crt involves: 129 * C57BL/6J J:55865 View
junctional epidermolysis bullosa non-Herlitz type Lamb3IAP/Lamb3IAP involves: C3H * C57BL/6 J:42382 View
junctional epidermolysis bullosa non-Herlitz type Lamc2jeb/Lamc2jeb 129X1/SvJ-Lamc2jeb J:158873 View
nonepidermolytic palmoplantar keratoderma Krt16tm1(KOMP)Vlcg/Krt16tm1(KOMP)Vlcg C57BL/6-Krt16tm1(KOMP)Vlcg J:184621 View
palmoplantar keratosis Slurp2tm1.1Sgy/Slurp2tm1.1Sgy involves: 129P2/OlaHsd * C57BL/6 J:231067 View
palmoplantar keratosis Slurp2tm1Lex/Slurp2tm1Lex involves: 129P2/OlaHsd * 129S5/SvEvBrd * C57BL/6 J:231067 View
palmoplantar keratosis Tuft1tm1a(KOMP)Wtsi/Tuft1tm1a(KOMP)Wtsi involves: C57BL/6N J:340887 View
pemphigus vulgaris Dsg3bal-Pas/Dsg3bal-Pas 129S2.Cg-Dsg3bal-Pas J:46865 View
pemphigus vulgaris Dsg3bal/Dsg3bal C57BL/6J-Dsg3bal/J J:42792 View
pemphigus vulgaris Dsg3tm1Stan/Dsg3tm1Stan involves: 129X1/SvJ * C57BL/6J J:40804 View
psoriasis Arpc4tm1c(EUCOMM)Wtsi/Arpc4tm1c(EUCOMM)Wtsi
Krt14tm1(cre)Wbm/Krt14+
B6.Cg-Arpc4tm1c(EUCOMM)Wtsi Krt14tm1(cre)Wbm J:253986 View
psoriasis Itgb2tm1Bay/Itgb2tm1Bay involves: 129S7/SvEvBrd * C57BL/6J * PL/J J:32126, J:84126 View
psoriasis Itgb2tm1Bay/Itgb2tm1Bay involves: 129S7/SvEvBrd * PL/J J:32126, J:109598 View
psoriasis Itgb2tm1Bay/Itgb2tm2Bay involves: 129S7/SvEvBrd * C57BL/6J * PL/J J:84126 View
psoriasis Itgb2tm1Bay/Itgb2tm2Bay PL.129S7-Itgb2tm1Bay Itgb2tm2Bay J:84126 View
psoriasis Itgb2tm2Bay/Itgb2tm2Bay involves: 129S7/SvEvBrd * PL/J J:84126 View
psoriasis Sptlc2tm1Yhir/Sptlc2tm1Yhir
Tg(KRT5-cre)1Tak/0
involves: C3H * C57BL/6 J:202388 View
psoriasis Tg(KRT5-rtTA)#Glk/0
Tg(tetO-S100a7a)#Yus/0
involves: FVB/N J:168000 View
psoriasis Ttc7fsn/Ttc7fsn involves: A/J * BALB/cByJ J:14506 View
recessive dystrophic epidermolysis bullosa Col7a1em#Jtol/Col7a1em#Jtol involves: 129S4/SvJae * BALB/c * C57BL/Ka * NOD J:280214 View
recessive dystrophic epidermolysis bullosa Col7a1tm1Lbt/Col7a1tm1Lbt involves: 129S1/Sv * 129X1/SvJ * C57BL/6Crl J:136145 View
recessive dystrophic epidermolysis bullosa Col7a1tm1Uit/Col7a1tm1Uit involves: 129S1/Sv J:155326 View
recessive dystrophic epidermolysis bullosa Col7a1tm1Uit/Col7a1tm1Uit involves: 129S1/Sv * C57BL/6J J:58533 View
recessive dystrophic epidermolysis bullosa Col7a1tm1Uit/Col7a1tm1Uit
Tg(KRT14-COL7A1*)1Shzu/0
involves: 129S1/Sv * C57BL/6 * DBA/2 J:155326 View
recessive dystrophic epidermolysis bullosa Grip1tm1Paw/Grip1tm1Paw involves: 129X1/SvJ * ICR J:79476 View
restrictive dermopathy Fsttm1Zuk/Fsttm1Zuk involves: 129S7/SvEvBrd J:23925 View
restrictive dermopathy Fsttm1Zuk/Fsttm1Zuk involves: 129S7/SvEvBrd * C57BL/6 J:23925 View
restrictive dermopathy Slc27a4tm1Wsr/Slc27a4tm1Wsr involves: 129P2/OlaHsd * C57BL/6 J:84096 View
restrictive dermopathy Slc27a4wrfr/Slc27a4wrfr involves: 129 * C57BL/6J J:83282 View
skin cancer Tg(KRT14-Snai1)1Efu/0 involves: CD-1 J:229072 View
skin disease Tg(Krt14-Fyn)AJsey/0 involves: C57BL/6 * CBA J:118155 View
skin melanoma Grm1Tg(p18A4.B)1352Szc/0 Not Specified J:83183 View
skin melanoma Tg(Dct-Grm1)ESzc/0 involves: C57BL/6J J:83183 View
skin squamous cell carcinoma Tg(KRT14-Fyn*)aJsey/0 involves: C57BL/6 * CBA * FVB/N J:155536 View
Stevens-Johnson syndrome Nfkbiztm1Aki/Nfkbiztm1Aki C.129P2-Nfkbiztm1Aki J:141704 View
Stevens-Johnson syndrome Nfkbiztm1Aki/Nfkbiztm1Aki involves: 129P2/OlaHsd J:96363 View
white sponge nevus Krt4Bcc1/Krt4+ C3HeB/FeJ-Krt4Bcc1 J:116740 View
white sponge nevus Krt4Bcc1/Krt4Bcc1 C3HeB/FeJ-Krt4Bcc1 J:116740 View
white sponge nevus Krt13em1Hcha/Krt13em1Hcha C57BL/6-Krt13em1Hcha J:297664 View
      atopic dermatitis Dock8tm1Ysfk/Dock8tm1Ysfk
Tg(TcrAND)53Hed/0
involves: C57BL/6 * SJL J:305132 View
basal cell carcinoma Dicer1tm1Snj/Dicer1tm1Snj
Trp53tm1Brn/Trp53+
Tg(KRT5-cre/PGR)1Der/0
involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6N * FVB/N * ICR J:216813 View
skin melanoma Cdkn2atm1Rdp/Cdkn2a+
Tg(Tyr-NRAS*Q61K)1Bee/?
involves: 129/Sv * C57BL/6 * DBA/2 * SJL J:98545 View
skin melanoma Cdkn2atm1Rdp/Cdkn2atm1Rdp
Tg(Tyr-NRAS*Q61K)1Bee/?
involves: 129/Sv * C57BL/6 * DBA/2 * SJL J:98545 View
skin melanoma Cdkn2atm2.1Nesh/Cdkn2atm2.1Nesh
Krastm4Tyj/Kras+
Tg(Tyr-cre/ERT2)13Bos/0
B6J.Cg-Tg(Tyr-cre/ERT2)13Bos Cdkn2atm2.1Nesh Krastm4Tyj J:220627 View
skin melanoma Cdkn2atm2.1Nesh/Cdkn2atm2.1Nesh
Nrastm1.1Nesh/Nrastm1.1Nesh
Stk11tm1.1Rdp/Stk11tm1.1Rdp
Tg(Tyr-cre/ERT2)13Bos/0
B6J.Cg-Tg(Tyr-cre/ERT2)13Bos Nrastm1.1Nesh Cdkn2atm2.1Nesh Stk11tm1.1Rdp J:220627 View
skin melanoma Cdkn2atm2.1Nesh/Cdkn2atm2.1Nesh
Nrastm1.1Nesh/Nrastm1.1Nesh
Tg(Tyr-cre/ERT2)13Bos/0
B6J.Cg-Tg(Tyr-cre/ERT2)13Bos Nrastm1.1Nesh Cdkn2atm2.1Nesh J:220627 View
Transgenes and
Other Mutations
     atopic dermatitis Tg(APOC1)1Lmh/Tg(APOC1)1Lmh involves: C57BL/6 J:135501 View
atopic dermatitis Tg(CD2-Stat6*V625A*T626A)78Mhk/0 involves: C3H * C57BL/6 J:160119 View
atopic dermatitis Tg(KRT14-CASP1)1Miz/0 involves: C57BL/6 J:78602 View
atopic dermatitis Tg(KRT14-VP16/NR1I2)13Sdub/? involves: C57BL/6 J:258435 View
atopic dermatitis Tg(SV40-KLK7)1010Teg/0 involves: C57BL/6J * CBA J:75714 View
cutis laxa Tg(CAG-ELN*)2Zu/0 C57BL/6J-Tg(CAG-ELN*)2Zu J:166809 View
cutis laxa Tg(CAG-ELN*)60Zu/0 C57BL/6J-Tg(CAG-ELN*)60Zu J:166809 View
dermatitis Tg(KRT5-IKBKB)1Armz/0 involves: C57BL/6 * DBA/2 J:160072 View
dermatitis Tg(KRT5-IKBKB)2Armz/0 involves: C57BL/6 * DBA/2 J:160072 View
Finnish type amyloidosis Tg(Ckm-GSN*D187N)AJewe/0 C57BL/6J-Tg(Ckm-GSN*D187N)AJewe J:150825 View
Finnish type amyloidosis Tg(Ckm-GSN*D187N)AJewe/Tg(Ckm-GSN*D187N)AJewe C57BL/6J-Tg(Ckm-GSN*D187N)AJewe J:150825 View
neonatal jaundice Ugt1tm1.1Afmu/Ugt1tm1.1Afmu FVB.Cg-Ugt1tm1.1Afmu J:216224 View
Netherton syndrome Tg(IVL-KLK5)#Hov/0 involves: C57BL/6 * CBA J:210758 View
psoriasis Tg(CAG-Lyn*)#Paau/0 B6.Cg-Tg(CAG-Lyn*)#Paau J:151886 View
psoriasis Tg(CYP1A1-PPARD)#Jfoe/0 involves: C57BL/6J * CBA J:158907 View
psoriasis Tg(ITGA2)1067Fmw/0
Tg(ITGB1)0840Fmw/0
involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(ITGA2)1067Fmw/0
Tg(ITGB1)0869Fmw/0
involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(ITGA2)1067Fmw/0
Tg(ITGB1)0870Fmw/0
involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(ITGA2)1070Fmw/0
Tg(ITGB1)0840Fmw/0
involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(ITGA2)1070Fmw/0
Tg(ITGB1)0869Fmw/0
involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(ITGA2)1070Fmw/0
Tg(ITGB1)0870Fmw/0
involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(ITGA2)1075Fmw/0
Tg(ITGB1)0840Fmw/0
involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(ITGA2)1075Fmw/0
Tg(ITGB1)0869Fmw/0
involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(ITGA2)1075Fmw/0
Tg(ITGB1)0870Fmw/0
involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(ITGA5)0794Fmw/0
Tg(ITGB1)0840Fmw/0
involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(ITGA5)0794Fmw/0
Tg(ITGB1)0869Fmw/0
involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(ITGA5)0794Fmw/0
Tg(ITGB1)0870Fmw/0
involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(ITGA5)0844Fmw/0
Tg(ITGB1)0840Fmw/0
involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(ITGA5)0844Fmw/0
Tg(ITGB1)0869Fmw/0
involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(ITGA5)0844Fmw/0
Tg(ITGB1)0870Fmw/0
involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(ITGA5)0858Fmw/0
Tg(ITGB1)0840Fmw/0
involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(ITGA5)0858Fmw/0
Tg(ITGB1)0869Fmw/0
involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(ITGA5)0858Fmw/0
Tg(ITGB1)0870Fmw/0
involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(ITGB1)0840Fmw/0 involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(ITGB1)0869Fmw/0 involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(ITGB1)0870Fmw/0 involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(KRT5-TGFB1)F2020Xjw/0 involves: C57BL/6 * DBA/2 * ICR J:90118 View
psoriasis Tg(KRT5-tTA)1216Glk/0
Tg(tetO-Tek)1Dmt/0
involves: CD-1 * FVB/N J:147438 View
psoriasis Tg(Krt14-Rac1*G12V)#Mrnk/0 either: B6.CBACa-Tg(Krt14-Rac1*G12V)#Mrnk or C.CBACa-Tg(Krt14-Rac1*G12V)#Mrnk J:237134 View
psoriasis Tg(Krt14-Rac1*G12V)#Mrnk/0 involves: CBA/CaJ J:237134 View
psoriasis Tg(Tek-tTA)1Dmt/0
Tg(tetO-Tek)1Dmt/0
involves: CD-1 J:96718 View
skin cancer Tg(KRT14-HPV8)9Vuc/0 FVB.Cg-Tg(KRT14-HPV8)9Vuc J:96784 View
skin cancer Tg(KRT14-HPV8)85Vuc/0 FVB.Cg-Tg(KRT14-HPV8)85Vuc J:96784 View
skin cancer Tg(KRT14-HPV8)#Vuc/0 involves: C57BL/6 * DBA * FVB/N J:96784 View
skin melanoma Tg(CAG-Ptafr)1Tksh/0 B6;D2-Tg(CAG-Ptafr)1Tksh/TkshRbrc J:38639 View
skin melanoma Tg(Mt1-RET)304Ina/0 B6.C-Tg(Mt1-RET)304Ina J:50392 View
skin squamous cell carcinoma Tg(KRT14-HPV16)wt1Dh/0 either: FVB.Cg-Tg(KRT14-HPV16)wt1Dh or (involves: C57BL/6 * DBA/2 * FVB/N) J:20130 View
Additional
Complex
Models
     atopic dermatitis Fgfr1tm1Upir/Fgfr1tm1Upir
Fgfr2tm1Dor/Fgfr2tm1Dor
Tg(KRT5-cre)5132Jlj/0
involves: 129X1/SvJ * C57BL/6 * C57BL/6J * DBA/2J J:221184 View
Birt-Hogg-Dube syndrome Fnip1tm1.2Baba/Fnip1+
Fnip2tm1.2Lss/Fnip2tm1.2Lss
involves: C57BL/6 J:220672 View
bullous pemphigoid Col17a1tm1.1(COL17A1)Zliu/Col17a1tm1.1(COL17A1)Zliu involves: 129P2/OlaHsd * C57BL/6J J:261781 View
dyskeratosis congenita Pot1btm1.1Schg/Pot1btm1.1Schg
Terctm1Rdp/Terc+
involves: 129/Sv * 129S6/SvEvTac * C57BL/6 * SJL J:144553 View
psoriasis Juntm4Wag/Juntm4Wag
Junbtm3Wag/Junbtm3Wag
Tg(Krt1-5-cre/ERT)1Ipc/0
involves: 129P2/OlaHsd * C57BL/6 * SJL J:116380 View
seborrheic keratosis Psen1tm1Bdes/Psen1+
Psen2tm1Bdes/Psen2tm1Bdes
involves: 129P2/OlaHsd J:91235 View
skin melanoma Braftm1Mmcm/Braf+
Ptentm1Rdp/Ptentm1Rdp
Tg(Tyr-cre/ERT2)13Bos/0
involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * FVB/N J:151023 View
skin melanoma Braftm1Mmcm/Braf+
Ptentm2.1Ppp/Ptentm2.1Ppp
Tg(Tyr-cre/ERT2)13Bos/0
involves: 129P2/OlaHsd * 129S1/Sv * FVB J:151023 View
skin melanoma Cdk4tm1.1Bbd/Cdk4tm1.1Bbd
Tg(Mt1-Hgf)#Lmb/0
B6.Cg-Cdk4tm1.1Bbd Tg(Mt1-Hgf)#Lmb J:111992 View
skin melanoma Cdk4tm1.1Bbd/Cdk4tm1.1Bbd
Tg(Tyr-NRAS*Q61K)1Bee/0
FVB.Cg-Cdk4tm1.1Bbd Tg(Tyr-NRAS*Q61K)1Bee J:222847 View
skin melanoma Xpatm1Tnka/Xpatm1Tnka
Tg(KRT14-Kitl)1Takk/?
involves: C57BL/6 * CBA * SJL J:100608 View


       
No similarity to the expected human disease phenotype was found.
        Disease Term Allelic Composition Genetic Background Reference Phenotypes
NOT Models      cherubism Sh3bp2tm1Bjro/Sh3bp2tm1Bjro
Tnftm1Gkl/Tnftm1Gkl
involves: 129S/SvEv * 129S4/SvJae * BALB/cJ * C57BL/6J J:117880 View
dyskeratosis congenita Dkc1tm2Pjma/Y chimera involves: 129X1/SvJ * C57BL/6J J:149894 View
dyskeratosis congenita Dkc1tm3Pjma/Dkc1tm3Pjma involves: 129X1/SvJ * C57BL/6J J:149894 View
dyskeratosis congenita Dkc1tm3Pjma/Y involves: 129X1/SvJ * C57BL/6J J:149894 View
Hailey-Hailey disease Atp2c1tm1Ges/Atp2c1+ involves: 129X1/SvJ * Black Swiss J:124662 View
psoriasis Itgb2tm1Bay/Itgb2tm2Bay B6.129S7-Itgb2tm1Bay Itgb2tm2Bay J:84126 View
skin squamous cell carcinoma Tg(KRT14-HPV16)wt1Dh/0 C.Cg-Tg(KRT14-HPV16)wt1Dh J:20130 View
skin squamous cell carcinoma Tg(KRT14-HPV16)wt1Dh/0 either: (involves: C57BL/6 * DBA/2) or (involves: C57BL/6 * DBA/2 * SENCAR * SSIN) J:20130 View
X-linked ichthyosis Foxp3sf/Y either: 129Rl.Cg-Foxp3sf or (involves: 101/Rl * C3Hf/Rl * STOCK MR) J:11262 View
X-linked ichthyosis Foxp3sf/Y involves: STOCK MR J:14076 View