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All mouse models of skin disease with phenotypic similarity to the human disease
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Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
atopic dermatitis |
Tg(KRT5-tTA)1216Glk/0 Tg(tetO-Il13)1Tazh/0 |
B6.Cg-Tg(KRT5-tTA)1216Glk Tg(tetO-Il13)1Tazh | J:150232 | View | ||||
atopic dermatitis | Tg(KRT14-Il4)#Lsch/0 | involves: BALB/cBy * C57BL/6 | J:126285 | View | ||||
atopic dermatitis | Tg(KRT14-Il18)#Knak/0 | C57BL/6-Tg(KRT14-Il18)#Knak | J:78602 | View | ||||
autosomal recessive congenital ichthyosis 1 | Tgm1tm1Kfyn/Tgm1tm1Kfyn | involves: 129S1/SvImJ * 129X1/SvJ * C57BL/6 | J:45653, J:74334 | View | ||||
autosomal recessive congenital ichthyosis 4B | Abca12el12/Abca12el12 | involves: 129/Sv * C57BL/6 | J:161652 | View | ||||
autosomal recessive congenital ichthyosis 4B | Abca12smsk/Abca12smsk | involves: C57BL/6J | J:262458 | View | ||||
autosomal recessive congenital ichthyosis 4B | Abca12tm1Lex/Abca12tm1Lex | involves: 129S/SvEvBrd * C57BL/6J | J:144062 | View | ||||
autosomal recessive congenital ichthyosis 4B | Abca12tm1Shzu/Abca12tm1Shzu | B6.129S-Abca12tm1Shzu | J:139048 | View | ||||
autosomal recessive congenital ichthyosis 10 | Pnpla1tm1a(KOMP)Wtsi/Pnpla1tm1a(KOMP)Wtsi | B6NTac;B6N-Atm1Brd Pnpla1tm1a(KOMP)Wtsi/Ics | J:242353 | View | ||||
autosomal recessive congenital ichthyosis 13 | Sdr9c7em1Maak/Sdr9c7em1Maak | involves: C57BL/6J | J:295441 | View | ||||
basal cell carcinoma |
Ptch1tm1Bjw/Ptch1tm1Bjw Tg(KRT14-cre)8Brn/0 |
involves: 129T2/SvEms * FVB/N | J:231264 | View | ||||
basal cell carcinoma |
Ptch1tm1Hahn/Ptch1tm1Hahn Gt(ROSA)26Sortm2(cre/ERT2)Brn/Gt(ROSA)26Sor+ |
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ | J:158915 | View | ||||
basal cell carcinoma | Ptch1tm1Mps/Ptch1+ | involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2J | J:58328 | View | ||||
Birt-Hogg-Dube syndrome |
Flcntm1Baba/Flcntm1.1Lss Tg(Cdh16-cre)91Igr/0 |
involves: C57BL/6 * FVB/N * ICR * SJL | J:130978 | View | ||||
Birt-Hogg-Dube syndrome |
Flcntm1Btt/Flcntm1Btt Tg(Cdh16-cre)91Igr/0 |
involves: 129S4/SvJaeSor * C57BL/6 * ICR | J:143922 | View | ||||
Bloch-Sulzberger syndrome | Ikbkgtm1Mka/Ikbkg+ | involves: 129S1/Sv * 129X1/SvJ * C57BL/6J | J:63054 | View | ||||
Bloch-Sulzberger syndrome | Ikbkgtm1Mpa/Ikbkg+ | involves: C57BL/6 | J:63055 | View | ||||
bullous congenital ichthyosiform erythroderma | Krt2Mhdadsk2/Krt2+ | C3HeB/FeJ-Krt2Mhdadsk2/Ieg | J:81301 | View | ||||
bullous congenital ichthyosiform erythroderma | Krt2Mhdadsk2/Krt2Mhdadsk2 | involves: C3HeB/FeJ * C57BL/6J | J:81301 | View | ||||
Carvajal syndrome | Dsprul/Dsprul | RB156Bnr/Ei-Dsprul/GrsrJ | J:217650 | View | ||||
cherubism | Sh3bp2tm1.1Ics/Sh3bp2tm1.1Ics | involves: 129S2/SvPas * C57BL/6 | J:221901 | View | ||||
cherubism | Sh3bp2tm1Bjro/Sh3bp2tm1Bjro | involves: 129S4/SvJae * BALB/cJ * C57BL/6J | J:117880 | View | ||||
cutaneous porphyria | Urostm1Cged/Urostm1Cged | involves: 129S2/SvPas | J:105776 | View | ||||
cutaneous porphyria | Urostm2Rjde/Urostm3Rjde | involves: 129S6/SvEvTac * C57BL/6 | J:132542 | View | ||||
cutaneous porphyria | Urostm3Rjde/Urostm3Rjde | involves: 129S6/SvEvTac * C57BL/6 | J:132542 | View | ||||
cutis laxa | Fbln5tm1Eno/Fbln5tm1Eno | involves: 129S6/SvEvTac | J:86754 | View | ||||
cutis laxa | Fbln5tm1Krc/Fbln5tm1Krc | involves: 129X1/SvJ * C57BL/6 | J:86753 | View | ||||
dyskeratosis congenita | Dkc1tm1.1Pjma/Y | B6.129X1(FVB)-Dkc1tm1.1Pjma | J:217050 | View | ||||
dyskeratosis congenita | Dkc1tm1Ppp/Dkc1+ | involves: 129S1/Sv | J:81054 | View | ||||
dyskeratosis congenita | Dkc1tm1Ppp/Y | involves: 129S1/Sv | J:81054 | View | ||||
epidermolysis bullosa simplex | Krt14tm1Der/Krt14tm1Der | involves: 129X1/SvJ | J:67320 | View | ||||
epidermolysis bullosa simplex | Krt14tm1Efu/Krt14tm1Efu | involves: 129 | J:25763 | View | ||||
epidermolysis bullosa simplex Ogna type | Plectm1Gwi/Plectm1Gwi | involves: 129S1/Sv * 129X1/SvJ | J:59000 | View | ||||
epidermolysis bullosa simplex Ogna type | Plectm2Gwi/Plectm2Gwi | involves: 129S1/Sv * 129X1/SvJ | J:59000 | View | ||||
epidermolysis bullosa simplex Ogna type | Plectm7.1Gwi/Plec+ | involves: 129P2/OlaHsd * C57BL/6 | J:179812 | View | ||||
epidermolysis bullosa simplex Ogna type | Plectm7.1Gwi/Plectm7.1Gwi | involves: 129P2/OlaHsd * C57BL/6 | J:179812 | View | ||||
epidermolytic hyperkeratosis | Krt1Mhdadsk12/Krt1+ | C3HeB/FeJ-Krt1Mhdadsk12 | J:108758 | View | ||||
epidermolytic hyperkeratosis | Krt10tm1Tmm/Krt10+ | either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * BALB/c * C57BL/6) | J:31853 | View | ||||
epidermolytic hyperkeratosis | Krt10tm1Tmm/Krt10tm1Tmm | either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * BALB/c * C57BL/6) | J:31853 | View | ||||
erythrokeratodermia variabilis | Gjb3tm2.1Kwi/Gjb3+ | involves: 129P2/OlaHsd * C57BL/6 | J:121802 | View | ||||
isolated anhidrosis with normal sweat glands | Itpr2tm1Kmik/Itpr2tm1Kmik | involves: 129S4/SvJae | J:217699 | View | ||||
junctional epidermolysis bullosa |
Col17a1em1Dcr/Col17a1em1Dcr Lamc2jeb/Lamc2jeb |
B6.Cg-Lamc2jeb Col17a1em1Dcr/Dcr | J:352187 | View | ||||
junctional epidermolysis bullosa |
Col17a1em2Dcr/Col17a1em2Dcr Lamc2jeb/Lamc2jeb |
C57BL/6J-Col17a1em2Dcr/Dcr | J:352187 | View | ||||
junctional epidermolysis bullosa |
Col17a1em8Dcr/Col17a1+ Lamc2jeb/Lamc2jeb |
B6.Cg-Lamc2jeb Col17a1em8Dcr/Dcr | J:352187 | View | ||||
junctional epidermolysis bullosa | Col17a1em8Dcr/Col17a1em8Dcr | C57BL/6J-Col17a1em8Dcr/DcrJ | J:352187 | View | ||||
junctional epidermolysis bullosa |
Lama3tm1Arte/Lama3tm1Arte Tg(KRT14-cre/ERT)20Efu/0 |
involves: C57BL/6 * CD-1 | J:240054 | View | ||||
junctional epidermolysis bullosa with pyloric atresia | Itgb4tm1Fgg/Itgb4tm1Fgg | involves: 129S1/Sv * C57BL/6 | J:48924 | View | ||||
keratosis follicularis | Atp2a2tm1Ges/Atp2a2+ | involves: 129X1/SvJ * Black Swiss | J:69754 | View | ||||
Kindler syndrome | Fermt1tm1Ref/Fermt1tm1Ref | involves: 129S1/Sv * 129X1/SvJ | J:142913 | View | ||||
mal de Meleda | Slurp1tm1.1Sgy/Slurp1tm1.1Sgy | involves: 129 * C57BL/6 | J:210836 | View | ||||
mal de Meleda | Slurp1tm1Lex/Slurp1tm1Lex | Not Specified | J:210836 | View | ||||
Netherton syndrome |
F2rl1tm1Cgh/F2rl1tm1Cgh Spink5tm1Hov/Spink5tm1Hov |
involves: 129P2/OlaHsd * 129S4/SvJae | J:180855 | View | ||||
Netherton syndrome | Spink5m1Btlr/Spink5m1Btlr | involves: C57BL/6J | J:183755 | View | ||||
Netherton syndrome | Spink5tm1Drh/Spink5tm1Drh | involves: 129P2/OlaHsd * C57BL/6 | J:95549 | View | ||||
Netherton syndrome | Spink5tm1Hov/Spink5tm1Hov | involves: 129P2/OlaHsd * FVB | J:96435 | View | ||||
Netherton syndrome | Spink5Tn(Pgk2-sb10,sb-Tyr)1498Ove/Spink5Tn(Pgk2-sb10,sb-Tyr)1498Ove | involves: FVB/N | J:93050 | View | ||||
psoriasis | Tg(KRT5-Stat3*A661C*N663C)1Jdg/0 | involves: FVB | J:95458 | View | ||||
psoriasis | Tg(KRT14-Vegfa)3Dtm/0 | FVB/N-Tg(KRT14-Vegfa)3Dtm | J:92643 | View | ||||
psoriasis 2 | Card14em2Tshu/Card14+ | involves: C57BL/6 | J:289239 | View | ||||
psoriasis 2 | Card14em9Lutzy/Card14+ | C57BL/6J-Card14em9Lutzy/J | J:262723 | View | ||||
Rothmund-Thomson syndrome |
ApcMin/Apc+ Recql4tm1Glu/Recql4tm1Glu |
involves: 129S7/SvEvBrd * C57BL/6J | J:97101 | View | ||||
Rothmund-Thomson syndrome | Recql4tm1Abe/Recql4tm1Abe | involves: 129S1/Sv * 129X1/SvJ * C57BL/6 | J:85574 | View | ||||
Rothmund-Thomson syndrome | Recql4tm1Glu/Recql4tm1Glu | involves: 129S7/SvEvBrd * C57BL/6J | J:97101 | View | ||||
alopecia areata | Cchcr1em1Aoka/Cchcr1em1Aoka | C57BL/6NJcl-Cchcr1em1Aoka | J:309941 | View | ||||
atopic dermatitis |
Adam17tm1.2Bbl/Adam17tm1.2Bbl Sox9tm3(cre)Crm/Sox9+ |
B6.129(SJL)-Sox9tm3(cre)Crm Adam17tm1.2Bbl | J:229771 | View | ||||
atopic dermatitis |
Casp8tm1Hed/Casp8tm1Hed Tg(KRT14-cre)1Efu/0 |
Not Specified | J:167299 | View | ||||
atopic dermatitis | Ctsetm1Kjy/Ctsetm1Kjy | involves: C57BL/6 | J:108745 | View | ||||
atopic dermatitis | Nfkbiatm1Stw/Nfkbiatm1Stw | involves: 129S1/Sv | J:32527 | View | ||||
atopic dermatitis | Nfkbiztm1Mamo/Nfkbiztm1Mamo | involves: 129S7/SvEvBrd | J:95040 | View | ||||
atopic dermatitis | Noa/Noa+ | NOA | J:43274 | View | ||||
atopic dermatitis | Relbtm1Brv/Relbtm1Brv | either: (involves: 129S2/SvPas) or (involves: C57BL/6) or (involves: 129S2/SvPas * C57BL/6) | J:63950 | View | ||||
atopic dermatitis | Sharpincpdm/Sharpincpdm | C57BL/KaLawRij-Sharpincpdm | J:14539, J:31745, J:116833 | View | ||||
atopic dermatitis |
Tg(KRT5-rtTA)1Glk/0 Tg(tetO/CMV-Tslp)#Sfz/0 |
involves: C3H * C57BL/6 * FVB/N | J:100506 | View | ||||
atopic dermatitis | Tmem79ma/Tmem79ma | B6.CBACaGr-Tmem79ma/J | J:202453 | View | ||||
atopic dermatitis | Tmem79ma/Tmem79ma | involves: C57BL/6JJcl * CBA/CaGr | J:202316 | View | ||||
atopic dermatitis | Traf3ip2adjm/Traf3ip2adjm | A.KOR-Traf3ip2adjm | J:162859 | View | ||||
atopic dermatitis | Traf3ip2adjm/Traf3ip2adjm | AK.KOR-Traf3ip2adjm | J:162859 | View | ||||
atopic dermatitis | Traf3ip2adjm/Traf3ip2adjm | B6.KOR-Traf3ip2adjm | J:162859 | View | ||||
atopic dermatitis | Traf3ip2adjm/Traf3ip2adjm | C.KOR-Traf3ip2adjm | J:162859 | View | ||||
atopic dermatitis | Traf3ip2adjm/Traf3ip2adjm | KOR-Traf3ip2adjm | J:162859 | View | ||||
atopic dermatitis | Trpv3Nh/Trpv3+ | involves: DS | J:42153 | View | ||||
atopic dermatitis |
Wasltm1.1Ttha/Wasltm1.1Ttha Tg(KRT14-cre)1Amc/0 |
involves: C57BL/6 * C57BL/6N * CBA | J:271857 | View | ||||
atopic dermatitis 2 | Flgft/Flgft | STOCK a/a Tmem79ma Flgft/J | J:204304 | View | ||||
autosomal recessive congenital ichthyosis 4B | Cst6ichq/Cst6+ | involves: BALB/cJ | J:41426, J:90417 | View | ||||
autosomal recessive congenital ichthyosis 4B |
Pigatm1Tak/Pigatm1Tak Tg(KRT5-cre)1Tak/0 |
involves: 129S1/Sv * 129X1/SvJ * C3H * C57BL/6 | J:91794 | View | ||||
autosomal recessive congenital ichthyosis 4B |
Pigatm1Tak/Y Tg(KRT5-cre)1Tak/0 |
involves: 129S1/Sv * 129X1/SvJ * C3H * C57BL/6 | J:91794 | View | ||||
autosomal recessive congenital ichthyosis 4B |
Prss8tm1.1Hum/Prss8tm1.2Hum Tg(KRT14-cre)1Ipc/0 |
involves: 129/Sv * C57BL/6 * FVB/N * SJL | J:100139 | View | ||||
Bloch-Sulzberger syndrome | NsdhlStr-1H/Nsdhl+ | involves: 101/H * C3H/HeH | J:106524 | View | ||||
cutaneous lupus erythematosus | Trex1tm1Tld/Trex1tm1Tld | involves: 129P2/OlaHsd * C57BL/6J | J:243357 | View | ||||
cutis laxa | Efemp2tm1.1Chu/Efemp2tm1.1Chu | B6(SJL)-Efemp2tm1.1Chu | J:223792 | View | ||||
cutis laxa | Ltbp4Gt(E301B04)Wrst/Ltbp4Gt(E301B04)Wrst | B6N.129P2-Ltbp4Gt(E301B04)Wrst | J:221200 | View | ||||
dermatomyositis | Tg(Krt14-Angptl2)1Yo/0 | C.Cg-Tg(Krt14-Angptl2)1Yo | J:181261 | View | ||||
dyskeratosis congenita | Tinf2tm2.2Tdl/Tinf2+ | involves: BALB/cJ * C57BL/6 | J:207367 | View | ||||
dyskeratosis congenita | Trp53tm1.1Tldo/Trp53tm1.1Tldo | involves: 129S2/SvPas * BALB/c * C57BL/6 | J:199308 | View | ||||
epidermal appendage tumor | Tg(Tff3-Tmem207)1Tamo/0 | C57BL/6-Tg(Tff3-Tmem207)1Tamo | J:217436 | View | ||||
epidermolysis bullosa simplex Dowling-Meara type | Krt5tm1Tmm/Krt5tm1Tmm | involves: 129P2/OlaHsd * BALB/c | J:76311 | View | ||||
epidermolysis bullosa simplex Dowling-Meara type |
Krt14tm1Der/Krt14+ Tg(KRT5-cre/PGR)1Der/? |
involves: 129X1/SvJ * FVB * ICR | J:67320 | View | ||||
epidermolysis bullosa simplex Dowling-Meara type |
Krt14tm1Der/Krt14+ Tg(KRT14-cre/PGR)1Der/? |
involves: 129X1/SvJ * FVB * ICR | J:67320 | View | ||||
epidermolysis bullosa simplex Dowling-Meara type | Krt14tm2Der/Krt14+ | involves: 129X1/SvJ | J:67320 | View | ||||
epidermolytic hyperkeratosis | Juptm1Kem/Juptm1Kem | involves: 129S1/Sv * 129X1/SvJ * C57BL/6 | J:38047 | View | ||||
ichthyosis vulgaris | Lbric-J/Lbric-J | involves: 129S4/SvJae * C57BL/6 | J:143838 | View | ||||
junctional epidermolysis bullosa Herlitz type | Itga6tm1Egl/Itga6tm1Egl | either: (involves: 129S2/SvPas * C57BL/6) or (involves: 129S2/SvPas * C57BL/6 * CD-1) | J:33712 | View | ||||
junctional epidermolysis bullosa Herlitz type | Lamb3IAP/Lamb3IAP | involves: C3H * C57BL/6 | J:42382 | View | ||||
junctional epidermolysis bullosa Herlitz type | Lamb3tm1.1Hosc/Lamb3tm1.1Hosc | involves: 129S4/SvJae * C57BL/6 | J:218616 | View | ||||
junctional epidermolysis bullosa Herlitz type | Lamc2tm1Uit/Lamc2tm1Uit | involves: C57BL/6 | J:85981 | View | ||||
junctional epidermolysis bullosa non-Herlitz type | Col17a1tm1Shzu/Col17a1tm1Shzu | B6.129S-Col17a1tm1Shzu | J:121695 | View | ||||
junctional epidermolysis bullosa non-Herlitz type | Itgb4tm1Efu/Itgb4tm1Efu | involves: 129S1/Sv * 129X1/SvJ * C57BL/6 | J:77644 | View | ||||
junctional epidermolysis bullosa non-Herlitz type | Lama3tm1Crt/Lama3tm1Crt | involves: 129 * C57BL/6J | J:55865 | View | ||||
junctional epidermolysis bullosa non-Herlitz type | Lamb3IAP/Lamb3IAP | involves: C3H * C57BL/6 | J:42382 | View | ||||
junctional epidermolysis bullosa non-Herlitz type | Lamc2jeb/Lamc2jeb | 129X1/SvJ-Lamc2jeb | J:158873 | View | ||||
nonepidermolytic palmoplantar keratoderma | Krt16tm1(KOMP)Vlcg/Krt16tm1(KOMP)Vlcg | C57BL/6-Krt16tm1(KOMP)Vlcg | J:184621 | View | ||||
palmoplantar keratosis | Slurp2tm1.1Sgy/Slurp2tm1.1Sgy | involves: 129P2/OlaHsd * C57BL/6 | J:231067 | View | ||||
palmoplantar keratosis | Slurp2tm1Lex/Slurp2tm1Lex | involves: 129P2/OlaHsd * 129S5/SvEvBrd * C57BL/6 | J:231067 | View | ||||
palmoplantar keratosis | Tuft1tm1a(KOMP)Wtsi/Tuft1tm1a(KOMP)Wtsi | involves: C57BL/6N | J:340887 | View | ||||
pemphigus vulgaris | Dsg3bal-Pas/Dsg3bal-Pas | 129S2.Cg-Dsg3bal-Pas | J:46865 | View | ||||
pemphigus vulgaris | Dsg3bal/Dsg3bal | C57BL/6J-Dsg3bal/J | J:42792 | View | ||||
pemphigus vulgaris | Dsg3tm1Stan/Dsg3tm1Stan | involves: 129X1/SvJ * C57BL/6J | J:40804 | View | ||||
psoriasis |
Arpc4tm1c(EUCOMM)Wtsi/Arpc4tm1c(EUCOMM)Wtsi Krt14tm1(cre)Wbm/Krt14+ |
B6.Cg-Arpc4tm1c(EUCOMM)Wtsi Krt14tm1(cre)Wbm | J:253986 | View | ||||
psoriasis | Itgb2tm1Bay/Itgb2tm1Bay | involves: 129S7/SvEvBrd * C57BL/6J * PL/J | J:32126, J:84126 | View | ||||
psoriasis | Itgb2tm1Bay/Itgb2tm1Bay | involves: 129S7/SvEvBrd * PL/J | J:32126, J:109598 | View | ||||
psoriasis | Itgb2tm1Bay/Itgb2tm2Bay | involves: 129S7/SvEvBrd * C57BL/6J * PL/J | J:84126 | View | ||||
psoriasis | Itgb2tm1Bay/Itgb2tm2Bay | PL.129S7-Itgb2tm1Bay Itgb2tm2Bay | J:84126 | View | ||||
psoriasis | Itgb2tm2Bay/Itgb2tm2Bay | involves: 129S7/SvEvBrd * PL/J | J:84126 | View | ||||
psoriasis |
Sptlc2tm1Yhir/Sptlc2tm1Yhir Tg(KRT5-cre)1Tak/0 |
involves: C3H * C57BL/6 | J:202388 | View | ||||
psoriasis |
Tg(KRT5-rtTA)#Glk/0 Tg(tetO-S100a7a)#Yus/0 |
involves: FVB/N | J:168000 | View | ||||
psoriasis | Ttc7fsn/Ttc7fsn | involves: A/J * BALB/cByJ | J:14506 | View | ||||
recessive dystrophic epidermolysis bullosa | Col7a1em#Jtol/Col7a1em#Jtol | involves: 129S4/SvJae * BALB/c * C57BL/Ka * NOD | J:280214 | View | ||||
recessive dystrophic epidermolysis bullosa | Col7a1tm1Lbt/Col7a1tm1Lbt | involves: 129S1/Sv * 129X1/SvJ * C57BL/6Crl | J:136145 | View | ||||
recessive dystrophic epidermolysis bullosa | Col7a1tm1Uit/Col7a1tm1Uit | involves: 129S1/Sv | J:155326 | View | ||||
recessive dystrophic epidermolysis bullosa | Col7a1tm1Uit/Col7a1tm1Uit | involves: 129S1/Sv * C57BL/6J | J:58533 | View | ||||
recessive dystrophic epidermolysis bullosa |
Col7a1tm1Uit/Col7a1tm1Uit Tg(KRT14-COL7A1*)1Shzu/0 |
involves: 129S1/Sv * C57BL/6 * DBA/2 | J:155326 | View | ||||
recessive dystrophic epidermolysis bullosa | Grip1tm1Paw/Grip1tm1Paw | involves: 129X1/SvJ * ICR | J:79476 | View | ||||
restrictive dermopathy | Fsttm1Zuk/Fsttm1Zuk | involves: 129S7/SvEvBrd | J:23925 | View | ||||
restrictive dermopathy | Fsttm1Zuk/Fsttm1Zuk | involves: 129S7/SvEvBrd * C57BL/6 | J:23925 | View | ||||
restrictive dermopathy | Slc27a4tm1Wsr/Slc27a4tm1Wsr | involves: 129P2/OlaHsd * C57BL/6 | J:84096 | View | ||||
restrictive dermopathy | Slc27a4wrfr/Slc27a4wrfr | involves: 129 * C57BL/6J | J:83282 | View | ||||
skin cancer | Tg(KRT14-Snai1)1Efu/0 | involves: CD-1 | J:229072 | View | ||||
skin disease | Tg(Krt14-Fyn)AJsey/0 | involves: C57BL/6 * CBA | J:118155 | View | ||||
skin melanoma | Grm1Tg(p18A4.B)1352Szc/0 | Not Specified | J:83183 | View | ||||
skin melanoma | Tg(Dct-Grm1)ESzc/0 | involves: C57BL/6J | J:83183 | View | ||||
skin squamous cell carcinoma | Tg(KRT14-Fyn*)aJsey/0 | involves: C57BL/6 * CBA * FVB/N | J:155536 | View | ||||
Stevens-Johnson syndrome | Nfkbiztm1Aki/Nfkbiztm1Aki | C.129P2-Nfkbiztm1Aki | J:141704 | View | ||||
Stevens-Johnson syndrome | Nfkbiztm1Aki/Nfkbiztm1Aki | involves: 129P2/OlaHsd | J:96363 | View | ||||
white sponge nevus | Krt4Bcc1/Krt4+ | C3HeB/FeJ-Krt4Bcc1 | J:116740 | View | ||||
white sponge nevus | Krt4Bcc1/Krt4Bcc1 | C3HeB/FeJ-Krt4Bcc1 | J:116740 | View | ||||
white sponge nevus | Krt13em1Hcha/Krt13em1Hcha | C57BL/6-Krt13em1Hcha | J:297664 | View | ||||
atopic dermatitis |
Dock8tm1Ysfk/Dock8tm1Ysfk Tg(TcrAND)53Hed/0 |
involves: C57BL/6 * SJL | J:305132 | View | ||||
basal cell carcinoma |
Dicer1tm1Snj/Dicer1tm1Snj Trp53tm1Brn/Trp53+ Tg(KRT5-cre/PGR)1Der/0 |
involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6N * FVB/N * ICR | J:216813 | View | ||||
skin melanoma |
Cdkn2atm1Rdp/Cdkn2a+ Tg(Tyr-NRAS*Q61K)1Bee/? |
involves: 129/Sv * C57BL/6 * DBA/2 * SJL | J:98545 | View | ||||
skin melanoma |
Cdkn2atm1Rdp/Cdkn2atm1Rdp Tg(Tyr-NRAS*Q61K)1Bee/? |
involves: 129/Sv * C57BL/6 * DBA/2 * SJL | J:98545 | View | ||||
skin melanoma |
Cdkn2atm2.1Nesh/Cdkn2atm2.1Nesh Krastm4Tyj/Kras+ Tg(Tyr-cre/ERT2)13Bos/0 |
B6J.Cg-Tg(Tyr-cre/ERT2)13Bos Cdkn2atm2.1Nesh Krastm4Tyj | J:220627 | View | ||||
skin melanoma |
Cdkn2atm2.1Nesh/Cdkn2atm2.1Nesh Nrastm1.1Nesh/Nrastm1.1Nesh Stk11tm1.1Rdp/Stk11tm1.1Rdp Tg(Tyr-cre/ERT2)13Bos/0 |
B6J.Cg-Tg(Tyr-cre/ERT2)13Bos Nrastm1.1Nesh Cdkn2atm2.1Nesh Stk11tm1.1Rdp | J:220627 | View | ||||
skin melanoma |
Cdkn2atm2.1Nesh/Cdkn2atm2.1Nesh Nrastm1.1Nesh/Nrastm1.1Nesh Tg(Tyr-cre/ERT2)13Bos/0 |
B6J.Cg-Tg(Tyr-cre/ERT2)13Bos Nrastm1.1Nesh Cdkn2atm2.1Nesh | J:220627 | View | ||||
Transgenes and Other Mutations | atopic dermatitis | Tg(APOC1)1Lmh/Tg(APOC1)1Lmh | involves: C57BL/6 | J:135501 | View | |||
atopic dermatitis | Tg(CD2-Stat6*V625A*T626A)78Mhk/0 | involves: C3H * C57BL/6 | J:160119 | View | ||||
atopic dermatitis | Tg(KRT14-CASP1)1Miz/0 | involves: C57BL/6 | J:78602 | View | ||||
atopic dermatitis | Tg(KRT14-VP16/NR1I2)13Sdub/? | involves: C57BL/6 | J:258435 | View | ||||
atopic dermatitis | Tg(SV40-KLK7)1010Teg/0 | involves: C57BL/6J * CBA | J:75714 | View | ||||
cutis laxa | Tg(CAG-ELN*)2Zu/0 | C57BL/6J-Tg(CAG-ELN*)2Zu | J:166809 | View | ||||
cutis laxa | Tg(CAG-ELN*)60Zu/0 | C57BL/6J-Tg(CAG-ELN*)60Zu | J:166809 | View | ||||
dermatitis | Tg(KRT5-IKBKB)1Armz/0 | involves: C57BL/6 * DBA/2 | J:160072 | View | ||||
dermatitis | Tg(KRT5-IKBKB)2Armz/0 | involves: C57BL/6 * DBA/2 | J:160072 | View | ||||
Finnish type amyloidosis | Tg(Ckm-GSN*D187N)AJewe/0 | C57BL/6J-Tg(Ckm-GSN*D187N)AJewe | J:150825 | View | ||||
Finnish type amyloidosis | Tg(Ckm-GSN*D187N)AJewe/Tg(Ckm-GSN*D187N)AJewe | C57BL/6J-Tg(Ckm-GSN*D187N)AJewe | J:150825 | View | ||||
neonatal jaundice | Ugt1tm1.1Afmu/Ugt1tm1.1Afmu | FVB.Cg-Ugt1tm1.1Afmu | J:216224 | View | ||||
Netherton syndrome | Tg(IVL-KLK5)#Hov/0 | involves: C57BL/6 * CBA | J:210758 | View | ||||
psoriasis | Tg(CAG-Lyn*)#Paau/0 | B6.Cg-Tg(CAG-Lyn*)#Paau | J:151886 | View | ||||
psoriasis | Tg(CYP1A1-PPARD)#Jfoe/0 | involves: C57BL/6J * CBA | J:158907 | View | ||||
psoriasis |
Tg(ITGA2)1067Fmw/0 Tg(ITGB1)0840Fmw/0 |
involves: C57BL/10 * CBA | J:30249 | View | ||||
psoriasis |
Tg(ITGA2)1067Fmw/0 Tg(ITGB1)0869Fmw/0 |
involves: C57BL/10 * CBA | J:30249 | View | ||||
psoriasis |
Tg(ITGA2)1067Fmw/0 Tg(ITGB1)0870Fmw/0 |
involves: C57BL/10 * CBA | J:30249 | View | ||||
psoriasis |
Tg(ITGA2)1070Fmw/0 Tg(ITGB1)0840Fmw/0 |
involves: C57BL/10 * CBA | J:30249 | View | ||||
psoriasis |
Tg(ITGA2)1070Fmw/0 Tg(ITGB1)0869Fmw/0 |
involves: C57BL/10 * CBA | J:30249 | View | ||||
psoriasis |
Tg(ITGA2)1070Fmw/0 Tg(ITGB1)0870Fmw/0 |
involves: C57BL/10 * CBA | J:30249 | View | ||||
psoriasis |
Tg(ITGA2)1075Fmw/0 Tg(ITGB1)0840Fmw/0 |
involves: C57BL/10 * CBA | J:30249 | View | ||||
psoriasis |
Tg(ITGA2)1075Fmw/0 Tg(ITGB1)0869Fmw/0 |
involves: C57BL/10 * CBA | J:30249 | View | ||||
psoriasis |
Tg(ITGA2)1075Fmw/0 Tg(ITGB1)0870Fmw/0 |
involves: C57BL/10 * CBA | J:30249 | View | ||||
psoriasis |
Tg(ITGA5)0794Fmw/0 Tg(ITGB1)0840Fmw/0 |
involves: C57BL/10 * CBA | J:30249 | View | ||||
psoriasis |
Tg(ITGA5)0794Fmw/0 Tg(ITGB1)0869Fmw/0 |
involves: C57BL/10 * CBA | J:30249 | View | ||||
psoriasis |
Tg(ITGA5)0794Fmw/0 Tg(ITGB1)0870Fmw/0 |
involves: C57BL/10 * CBA | J:30249 | View | ||||
psoriasis |
Tg(ITGA5)0844Fmw/0 Tg(ITGB1)0840Fmw/0 |
involves: C57BL/10 * CBA | J:30249 | View | ||||
psoriasis |
Tg(ITGA5)0844Fmw/0 Tg(ITGB1)0869Fmw/0 |
involves: C57BL/10 * CBA | J:30249 | View | ||||
psoriasis |
Tg(ITGA5)0844Fmw/0 Tg(ITGB1)0870Fmw/0 |
involves: C57BL/10 * CBA | J:30249 | View | ||||
psoriasis |
Tg(ITGA5)0858Fmw/0 Tg(ITGB1)0840Fmw/0 |
involves: C57BL/10 * CBA | J:30249 | View | ||||
psoriasis |
Tg(ITGA5)0858Fmw/0 Tg(ITGB1)0869Fmw/0 |
involves: C57BL/10 * CBA | J:30249 | View | ||||
psoriasis |
Tg(ITGA5)0858Fmw/0 Tg(ITGB1)0870Fmw/0 |
involves: C57BL/10 * CBA | J:30249 | View | ||||
psoriasis | Tg(ITGB1)0840Fmw/0 | involves: C57BL/10 * CBA | J:30249 | View | ||||
psoriasis | Tg(ITGB1)0869Fmw/0 | involves: C57BL/10 * CBA | J:30249 | View | ||||
psoriasis | Tg(ITGB1)0870Fmw/0 | involves: C57BL/10 * CBA | J:30249 | View | ||||
psoriasis | Tg(KRT5-TGFB1)F2020Xjw/0 | involves: C57BL/6 * DBA/2 * ICR | J:90118 | View | ||||
psoriasis |
Tg(KRT5-tTA)1216Glk/0 Tg(tetO-Tek)1Dmt/0 |
involves: CD-1 * FVB/N | J:147438 | View | ||||
psoriasis | Tg(Krt14-Rac1*G12V)#Mrnk/0 | either: B6.CBACa-Tg(Krt14-Rac1*G12V)#Mrnk or C.CBACa-Tg(Krt14-Rac1*G12V)#Mrnk | J:237134 | View | ||||
psoriasis | Tg(Krt14-Rac1*G12V)#Mrnk/0 | involves: CBA/CaJ | J:237134 | View | ||||
psoriasis |
Tg(Tek-tTA)1Dmt/0 Tg(tetO-Tek)1Dmt/0 |
involves: CD-1 | J:96718 | View | ||||
skin cancer | Tg(KRT14-HPV8)9Vuc/0 | FVB.Cg-Tg(KRT14-HPV8)9Vuc | J:96784 | View | ||||
skin cancer | Tg(KRT14-HPV8)85Vuc/0 | FVB.Cg-Tg(KRT14-HPV8)85Vuc | J:96784 | View | ||||
skin cancer | Tg(KRT14-HPV8)#Vuc/0 | involves: C57BL/6 * DBA * FVB/N | J:96784 | View | ||||
skin melanoma | Tg(CAG-Ptafr)1Tksh/0 | B6;D2-Tg(CAG-Ptafr)1Tksh/TkshRbrc | J:38639 | View | ||||
skin melanoma | Tg(Mt1-RET)304Ina/0 | B6.C-Tg(Mt1-RET)304Ina | J:50392 | View | ||||
skin squamous cell carcinoma | Tg(KRT14-HPV16)wt1Dh/0 | either: FVB.Cg-Tg(KRT14-HPV16)wt1Dh or (involves: C57BL/6 * DBA/2 * FVB/N) | J:20130 | View | ||||
Additional Complex Models | atopic dermatitis |
Fgfr1tm1Upir/Fgfr1tm1Upir Fgfr2tm1Dor/Fgfr2tm1Dor Tg(KRT5-cre)5132Jlj/0 |
involves: 129X1/SvJ * C57BL/6 * C57BL/6J * DBA/2J | J:221184 | View | |||
Birt-Hogg-Dube syndrome |
Fnip1tm1.2Baba/Fnip1+ Fnip2tm1.2Lss/Fnip2tm1.2Lss |
involves: C57BL/6 | J:220672 | View | ||||
bullous pemphigoid | Col17a1tm1.1(COL17A1)Zliu/Col17a1tm1.1(COL17A1)Zliu | involves: 129P2/OlaHsd * C57BL/6J | J:261781 | View | ||||
dyskeratosis congenita |
Pot1btm1.1Schg/Pot1btm1.1Schg Terctm1Rdp/Terc+ |
involves: 129/Sv * 129S6/SvEvTac * C57BL/6 * SJL | J:144553 | View | ||||
psoriasis |
Juntm4Wag/Juntm4Wag Junbtm3Wag/Junbtm3Wag Tg(Krt1-5-cre/ERT)1Ipc/0 |
involves: 129P2/OlaHsd * C57BL/6 * SJL | J:116380 | View | ||||
seborrheic keratosis |
Psen1tm1Bdes/Psen1+ Psen2tm1Bdes/Psen2tm1Bdes |
involves: 129P2/OlaHsd | J:91235 | View | ||||
skin melanoma |
Braftm1Mmcm/Braf+ Ptentm1Rdp/Ptentm1Rdp Tg(Tyr-cre/ERT2)13Bos/0 |
involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * FVB/N | J:151023 | View | ||||
skin melanoma |
Braftm1Mmcm/Braf+ Ptentm2.1Ppp/Ptentm2.1Ppp Tg(Tyr-cre/ERT2)13Bos/0 |
involves: 129P2/OlaHsd * 129S1/Sv * FVB | J:151023 | View | ||||
skin melanoma |
Cdk4tm1.1Bbd/Cdk4tm1.1Bbd Tg(Mt1-Hgf)#Lmb/0 |
B6.Cg-Cdk4tm1.1Bbd Tg(Mt1-Hgf)#Lmb | J:111992 | View | ||||
skin melanoma |
Cdk4tm1.1Bbd/Cdk4tm1.1Bbd Tg(Tyr-NRAS*Q61K)1Bee/0 |
FVB.Cg-Cdk4tm1.1Bbd Tg(Tyr-NRAS*Q61K)1Bee | J:222847 | View | ||||
skin melanoma |
Xpatm1Tnka/Xpatm1Tnka Tg(KRT14-Kitl)1Takk/? |
involves: C57BL/6 * CBA * SJL | J:100608 | View |
No similarity to the expected human disease phenotype was found.
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Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
NOT Models | cherubism |
Sh3bp2tm1Bjro/Sh3bp2tm1Bjro Tnftm1Gkl/Tnftm1Gkl |
involves: 129S/SvEv * 129S4/SvJae * BALB/cJ * C57BL/6J | J:117880 | View | |||
dyskeratosis congenita | Dkc1tm2Pjma/Y | chimera involves: 129X1/SvJ * C57BL/6J | J:149894 | View | ||||
dyskeratosis congenita | Dkc1tm3Pjma/Dkc1tm3Pjma | involves: 129X1/SvJ * C57BL/6J | J:149894 | View | ||||
dyskeratosis congenita | Dkc1tm3Pjma/Y | involves: 129X1/SvJ * C57BL/6J | J:149894 | View | ||||
Hailey-Hailey disease | Atp2c1tm1Ges/Atp2c1+ | involves: 129X1/SvJ * Black Swiss | J:124662 | View | ||||
psoriasis | Itgb2tm1Bay/Itgb2tm2Bay | B6.129S7-Itgb2tm1Bay Itgb2tm2Bay | J:84126 | View | ||||
skin squamous cell carcinoma | Tg(KRT14-HPV16)wt1Dh/0 | C.Cg-Tg(KRT14-HPV16)wt1Dh | J:20130 | View | ||||
skin squamous cell carcinoma | Tg(KRT14-HPV16)wt1Dh/0 | either: (involves: C57BL/6 * DBA/2) or (involves: C57BL/6 * DBA/2 * SENCAR * SSIN) | J:20130 | View | ||||
X-linked ichthyosis | Foxp3sf/Y | either: 129Rl.Cg-Foxp3sf or (involves: 101/Rl * C3Hf/Rl * STOCK MR) | J:11262 | View | ||||
X-linked ichthyosis | Foxp3sf/Y | involves: STOCK MR | J:14076 | View |