Excel File Text File All mouse models of mouth disease with phenotypic similarity to the human disease
        Disease Term Allelic Composition Genetic Background Reference Phenotypes
      amelogenesis imperfecta hypomaturation type 2A2 Mmp20tm1Jdb/Mmp20tm1Jdb involves: 129P2/OlaHsd * C57BL/6 J:80925 View
amelogenesis imperfecta hypomaturation type 2A3 Wdr72tm1a(KOMP)Wtsi/Wdr72tm1a(KOMP)Wtsi involves: C57BL/6N J:215636 View
amelogenesis imperfecta type 1B EnamRgsc395/Enam+ involves: C57BL/6JJcl * DBA/2J J:96349 View
amelogenesis imperfecta type 1B EnamRgsc514/Enam+ involves: C57BL/6JJcl * DBA/2J J:96349 View
amelogenesis imperfecta type 1B EnamRgsc521/Enam+ involves: C57BL/6JJcl * DBA/2J J:96349 View
amelogenesis imperfecta type 1B EnamRgsc521/EnamRgsc521 involves: C57BL/6JJcl * DBA/2J J:96349 View
amelogenesis imperfecta type 1B Enamtm1.1Jcch/Enam+ involves: C57BL/6 J:223123 View
amelogenesis imperfecta type 1B Enamtm1.1Jcch/Enamtm1.1Jcch involves: C57BL/6 J:223123 View
amelogenesis imperfecta type 1E AmelxRgsc888/Amelx+ involves: C57BL/6JJcl * DBA/2J J:157947 View
amelogenesis imperfecta type 1E AmelxRgsc888/AmelxRgsc888 involves: C57BL/6JJcl * DBA/2J J:157947 View
amelogenesis imperfecta type 1E AmelxRgsc888/Y involves: C57BL/6JJcl * DBA/2J J:157947 View
amelogenesis imperfecta type 1E Amelxtm1Kul/Amelxtm1Kul involves: 129S1/Sv * 129X1/SvJ * C57BL/6 J:71126 View
amelogenesis imperfecta type 1E Amelxtm1Kul/Amelxtm1Kul
Tg(AMELX*P70T)2Gibs/?
involves: 129S1/Sv * 129X1/SvJ J:122914 View
amelogenesis imperfecta type 1E Tg(AMELX*P70T)2Gibs/? Not Specified J:122914 View
amelogenesis imperfecta type 3C Reltem1Jpsi/Reltem1Jpsi C57BL/6-Reltem1Jpsi J:279949 View
cleft lip Irf6tm1Bcsl/Irf6tm1Bcsl
Pitx2tm4(cre)Jfm/Pitx2+
involves: 129 J:275989 View
dentinogenesis imperfecta Dspptm1Kul/Dspptm1Kul involves: 129/Sv * C57BL/6 J:84378 View
tooth agenesis Msx1tm1Bero/Msx1tm1Bero B6.129P2-Msx1tm1Bero J:42035 View
tooth agenesis Msx1tm1Rilm/Msx1tm1Rilm either: (involves: 129S4/SvJae-Msx1tm1Rilm) or (involves: 129S4/SvJae * BALB/c) or (involves: 129X1/SvJae * C57BL/6J) J:17489 View
tooth agenesis Msx1tm1Rilm/Msx1tm1Rilm
Msx2tm1Rilm/Msx2tm1Rilm
involves: 129S4/SvJae * BALB/c * CD-1 J:61509 View
tooth agenesis Pax9tm1Hpt/Pax9tm1Hpt involves: 129S2/SvPas * C57BL/6 J:104121 View
tooth agenesis Pax9tm1Hpt/Pax9tm1Rbal involves: 129 * C57BL/6 * CD-1 J:104121 View
      aggressive periodontitis Postntm1Sjc/Postntm1Sjc involves: C57BL/6 J:103753 View
ankyloglossia Lgr5tm1Ah/Lgr5tm1Ah involves: 129S5/SvEvBrd * C57BL/6 J:94196 View
dentin dysplasia Ssu2tm1.1Xmx/Ssu2+ involves: 129S6/SvEvTac * C57BL/6J J:240559 View
dentin dysplasia Ssu2tm1.1Xmx/Ssu2tm1.1Xmx involves: 129S6/SvEvTac * C57BL/6J J:240559 View
periodontal disease Dspptm1Kul/Dspptm1Kul B6;129-Dspptm1Kul/Mmnc J:241990 View
salivary gland cancer Gon4ljusty/Gon4ljusty C3HeB/FeJ-Gon4ljusty J:197352 View
Transgenes and
Other Mutations
     amelogenesis imperfecta Tg(Amelx-Ambn)1Mlp/Tg(Amelx-Ambn)1Mlp Not Specified J:83576 View
dentin dysplasia Tg(Dspp-TGFB1)3Kul/? FVB/N-Tg(Dspp-TGFB1)3Kul J:118918 View
Additional
Complex
Models
     oral cavity cancer Krastm4Tyj/Kras+
Tg(CAG-HPV16E6E7,-luc)#Mspi/0
Tg(KRT14-cre/ERT)20Efu/0
involves: 129S4/SvJae * C57BL/6 * CD-1 * FVB/N * FVB/NJ J:210533 View
salivary gland carcinoma Bmpr1atm2.1Bhr/Bmpr1atm2.1Bhr
Ctnnb1tm1Mmt/Ctnnb1+
Krt14tm1.1(cre)Wbm/Krt14+
involves: 129P2/OlaHsd * 129S7/SvEvBrd * 129X1/SvJ J:199091 View


       
No similarity to the expected human disease phenotype was found.
        Disease Term Allelic Composition Genetic Background Reference Phenotypes
NOT Models      amelogenesis imperfecta type 1E Tg(Amelx)42Msnd/Tg(Amelx)42Msnd involves: C57BL/6J * CBA/J * DBA/2J J:100004 View