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All mouse models of mouth disease with phenotypic similarity to the human disease
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Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
amelogenesis imperfecta hypomaturation type 2A2 | Mmp20tm1Jdb/Mmp20tm1Jdb | involves: 129P2/OlaHsd * C57BL/6 | J:80925 | View | ||||
amelogenesis imperfecta hypomaturation type 2A3 | Wdr72tm1a(KOMP)Wtsi/Wdr72tm1a(KOMP)Wtsi | involves: C57BL/6N | J:215636 | View | ||||
amelogenesis imperfecta type 1B | EnamRgsc395/Enam+ | involves: C57BL/6JJcl * DBA/2J | J:96349 | View | ||||
amelogenesis imperfecta type 1B | EnamRgsc514/Enam+ | involves: C57BL/6JJcl * DBA/2J | J:96349 | View | ||||
amelogenesis imperfecta type 1B | EnamRgsc521/Enam+ | involves: C57BL/6JJcl * DBA/2J | J:96349 | View | ||||
amelogenesis imperfecta type 1B | EnamRgsc521/EnamRgsc521 | involves: C57BL/6JJcl * DBA/2J | J:96349 | View | ||||
amelogenesis imperfecta type 1B | Enamtm1.1Jcch/Enam+ | involves: C57BL/6 | J:223123 | View | ||||
amelogenesis imperfecta type 1B | Enamtm1.1Jcch/Enamtm1.1Jcch | involves: C57BL/6 | J:223123 | View | ||||
amelogenesis imperfecta type 1E | AmelxRgsc888/Amelx+ | involves: C57BL/6JJcl * DBA/2J | J:157947 | View | ||||
amelogenesis imperfecta type 1E | AmelxRgsc888/AmelxRgsc888 | involves: C57BL/6JJcl * DBA/2J | J:157947 | View | ||||
amelogenesis imperfecta type 1E | AmelxRgsc888/Y | involves: C57BL/6JJcl * DBA/2J | J:157947 | View | ||||
amelogenesis imperfecta type 1E | Amelxtm1Kul/Amelxtm1Kul | involves: 129S1/Sv * 129X1/SvJ * C57BL/6 | J:71126 | View | ||||
amelogenesis imperfecta type 1E |
Amelxtm1Kul/Amelxtm1Kul Tg(AMELX*P70T)2Gibs/? |
involves: 129S1/Sv * 129X1/SvJ | J:122914 | View | ||||
amelogenesis imperfecta type 1E | Tg(AMELX*P70T)2Gibs/? | Not Specified | J:122914 | View | ||||
amelogenesis imperfecta type 3C | Reltem1Jpsi/Reltem1Jpsi | C57BL/6-Reltem1Jpsi | J:279949 | View | ||||
cleft lip |
Irf6tm1Bcsl/Irf6tm1Bcsl Pitx2tm4(cre)Jfm/Pitx2+ |
involves: 129 | J:275989 | View | ||||
dentinogenesis imperfecta | Dspptm1Kul/Dspptm1Kul | involves: 129/Sv * C57BL/6 | J:84378 | View | ||||
tooth agenesis | Msx1tm1Bero/Msx1tm1Bero | B6.129P2-Msx1tm1Bero | J:42035 | View | ||||
tooth agenesis | Msx1tm1Rilm/Msx1tm1Rilm | either: (involves: 129S4/SvJae-Msx1tm1Rilm) or (involves: 129S4/SvJae * BALB/c) or (involves: 129X1/SvJae * C57BL/6J) | J:17489 | View | ||||
tooth agenesis |
Msx1tm1Rilm/Msx1tm1Rilm Msx2tm1Rilm/Msx2tm1Rilm |
involves: 129S4/SvJae * BALB/c * CD-1 | J:61509 | View | ||||
tooth agenesis | Pax9tm1Hpt/Pax9tm1Hpt | involves: 129S2/SvPas * C57BL/6 | J:104121 | View | ||||
tooth agenesis | Pax9tm1Hpt/Pax9tm1Rbal | involves: 129 * C57BL/6 * CD-1 | J:104121 | View | ||||
aggressive periodontitis | Postntm1Sjc/Postntm1Sjc | involves: C57BL/6 | J:103753 | View | ||||
ankyloglossia | Lgr5tm1Ah/Lgr5tm1Ah | involves: 129S5/SvEvBrd * C57BL/6 | J:94196 | View | ||||
dentin dysplasia | Ssu2tm1.1Xmx/Ssu2+ | involves: 129S6/SvEvTac * C57BL/6J | J:240559 | View | ||||
dentin dysplasia | Ssu2tm1.1Xmx/Ssu2tm1.1Xmx | involves: 129S6/SvEvTac * C57BL/6J | J:240559 | View | ||||
periodontal disease | Dspptm1Kul/Dspptm1Kul | B6;129-Dspptm1Kul/Mmnc | J:241990 | View | ||||
salivary gland cancer | Gon4ljusty/Gon4ljusty | C3HeB/FeJ-Gon4ljusty | J:197352 | View | ||||
Transgenes and Other Mutations | amelogenesis imperfecta | Tg(Amelx-Ambn)1Mlp/Tg(Amelx-Ambn)1Mlp | Not Specified | J:83576 | View | |||
dentin dysplasia | Tg(Dspp-TGFB1)3Kul/? | FVB/N-Tg(Dspp-TGFB1)3Kul | J:118918 | View | ||||
Additional Complex Models | oral cavity cancer |
Krastm4Tyj/Kras+ Tg(CAG-HPV16E6E7,-luc)#Mspi/0 Tg(KRT14-cre/ERT)20Efu/0 |
involves: 129S4/SvJae * C57BL/6 * CD-1 * FVB/N * FVB/NJ | J:210533 | View | |||
salivary gland carcinoma |
Bmpr1atm2.1Bhr/Bmpr1atm2.1Bhr Ctnnb1tm1Mmt/Ctnnb1+ Krt14tm1.1(cre)Wbm/Krt14+ |
involves: 129P2/OlaHsd * 129S7/SvEvBrd * 129X1/SvJ | J:199091 | View |
No similarity to the expected human disease phenotype was found.
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Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
NOT Models | amelogenesis imperfecta type 1E | Tg(Amelx)42Msnd/Tg(Amelx)42Msnd | involves: C57BL/6J * CBA/J * DBA/2J | J:100004 | View |