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All mouse models of heart valve disease with phenotypic similarity to the human disease
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Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
mitral valve prolapse | Dchs1tm1.2Irv/Dchs1+ | involves: 129S7/SvEvBrd * C57BL/6 | J:225789 | View | ||||
mitral valve prolapse | Dzip1em1Sasl/Dzip1+ | C57BL/6J-Dzip1em1Sasl | J:291454 | View | ||||
mitral valve prolapse |
Dzip1tm1Sasl/Dzip1tm1Sasl Nfatc1tm1.1(cre)Bz/Nfatc1+ |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J | J:291454 | View | ||||
supravalvular aortic stenosis | Elntm1Dyl/Eln+ | B6.129-Elntm1Dyl | J:86535 | View | ||||
supravalvular aortic stenosis | Elntm1Dyl/Eln+ | involves: 129S1/Sv * 129X1/SvJ * C57BL/6J | J:51109 | View | ||||
aortic valve disease | Adamts19tm4a(EUCOMM)Wtsi/Adamts19tm4a(EUCOMM)Wtsi | C57BL/6N-Adamts19tm4a(EUCOMM)Wtsi | J:287334 | View | ||||
aortic valve disease | Adamts19tm4b(EUCOMM)Wtsi/Adamts19tm4b(EUCOMM)Wtsi | B6N(Cg)-Adamts19tm4b(EUCOMM)Wtsi | J:287334 | View | ||||
aortic valve disease | Egfrwa2/Egfrwa2 | involves: C57BL/6 | J:241813 | View | ||||
aortic valve disease | Egfrwa2/Egfrwa2 | STOCK Egfrwa2 | J:60750 | View | ||||
aortic valve disease | Elntm1Dyl/Eln+ | involves: 129S1/Sv * 129X1/SvJ * C57BL/6 | J:184494 | View | ||||
aortic valve disease | Hey2tm1Kkb/Hey2tm1Kkb | involves: 129S7/SvEvBrd * C57BL/6 | J:216895 | View | ||||
aortic valve disease | Nos3tm1Unc/Nos3tm1Unc | B6.129P2-Nos3tm1Unc/J | J:103340 | View | ||||
aortic valve disease | Rbpjtm1Kyo/Rbpj+ | involves: 129S2/SvPas * CD-1 | J:187551 | View | ||||
aortic valve stenosis | Tnftm2Gkl/Tnf+ | involves: 129S/SvEv * C57BL/6J | J:264147 | View | ||||
Ebstein anomaly |
Bmpr1atm1Bhr/Bmpr1atm2.1Bhr Tg(GATA6-cre)#Jbeb/0 |
involves: 129S7/SvEvBrd * C57BL/6 * FVB | J:111392 | View | ||||
heart valve disease | Galnt1tm1.1Jxm/Galnt1tm1.1Jxm | B6NHsd.Cg-Galnt1tm1.1Jxm | J:242253 | View | ||||
heart valve disease | TnfBpsm1/Tnf+ | C.Cg-TnfBpsm1 | J:226052 | View | ||||
mitral valve disease |
Ift88tm1Bky/Ift88tm1Bky Nfatc1tm1.1(cre)Bz/Nfatc1+ |
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ | J:291454 | View | ||||
tricuspid atresia | Zfpm2tm1Jml/Zfpm2tm1Jml | involves: 129X1/SvJ | J:63121 | View | ||||
Additional Complex Models | aortic valve disease |
Apobtm2Sgy/Apobtm2Sgy Ldlrtm1Her/Ldlrtm1Her Tg(Ins-Igf2)1Fbos/? |
involves: 129S7/SvEvBrd * C57BL/6 * C57BL/6J * SJL | J:227165 | View | |||
mitral valve disease |
H2b/H2g7 Tg(TcraR28,TcrbR28)KRNDim/0 |
involves: C57BL/6 * NOD * SJL | J:275827 | View |