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All mouse models of Gerstmann-Straussler-Scheinker syndrome with phenotypic similarity to the human disease
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Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
Gerstmann-Straussler-Scheinker syndrome |
Prnptm1Cwe/Prnptm1Cwe Tg(Prnp*A116V*M128V)1309Jama/0 |
involves: 129S7/SvEvBrd | J:151934 | View | ||||
Gerstmann-Straussler-Scheinker syndrome |
Prnptm1Cwe/Prnptm1Cwe Tg(Prnp*P101L)2866Sbp/0 |
involves: 129S7/SvEvBrd * FVB/N | J:136434 | View | ||||
Gerstmann-Straussler-Scheinker syndrome |
Prnptm1Cwe/Prnptm1Cwe Tg(Prnp*P101L)2866Sbp/Tg(Prnp*P101L)2866Sbp |
involves: 129S7/SvEvBrd * FVB/N | J:136434 | View | ||||
Gerstmann-Straussler-Scheinker syndrome | Tg(Prnp*P101L)174Sbp/0 | involves: C57BL/6 * SJL | J:127373 | View | ||||
Gerstmann-Straussler-Scheinker syndrome | Tg(Prnp*P101L)2247Sbp/0 | involves: FVB/N | J:136434 | View | ||||
Gerstmann-Straussler-Scheinker syndrome | Tg(Prnp*P101L)2862Sbp/0 | involves: FVB/N | J:136434 | View | ||||
Gerstmann-Straussler-Scheinker syndrome | Tg(Prnp*P101L)2866Sbp/0 | involves: FVB/N | J:136434 | View |
No similarity to the expected human disease phenotype was found.
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Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
NOT Models | Gerstmann-Straussler-Scheinker syndrome | Prnptm1Cwe/Prnptm1Cwe | involves: 129S7/SvEvBrd * C57BL/6 | J:472 | View | |||
Gerstmann-Straussler-Scheinker syndrome | Prnptm1Edin/Prnptm1Edin | 129P2/OlaHsd-Prnptm1Edin/EdinH | J:58820 | View | ||||
Gerstmann-Straussler-Scheinker syndrome | Prnptm1Rcm/Prnptm1Rcm | 129P2/OlaHsd-Prnptm1Rcm | J:45908 | View |