Excel File Text File All mouse models of holoprosencephaly with phenotypic similarity to the human disease
        Disease Term Allelic Composition Genetic Background Reference Phenotypes
      holoprosencephaly 2 Six3tm1Gco/Six3tm1Gco involves: 129S1/Sv J:81797 View
holoprosencephaly 2 Six3tm3.1Gco/Six3+
Shhtm1Chg/Shh+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 J:140315 View
holoprosencephaly 2 Six3tm3Gco/Six3tm3Gco
Foxg1tm1(cre)Skm/Foxg1+
involves: 129S1/Sv * C57BL/6 J:140315 View
holoprosencephaly 2 Six3tm4(cre/ERT2)Gco/Six3+ involves: 129S1/Sv * C57BL/6 J:140315 View
holoprosencephaly 3 Disp1icb/Disp1tm1Amc
Shhtm1Amc/Shh+
involves: 129X1/SvJ * C57BL/6J J:92058 View
holoprosencephaly 3 Shhtm1Chg/Shhtm1Chg involves: 129S1/Sv * 129X1/SvJ J:35802 View
holoprosencephaly 3 Shhtm1Chg/Shhtm1Chg involves: C57BL/6 J:89364 View
holoprosencephaly 5 Zic2Ku/Zic2Ku 129S.CAnNCrl(C3)-Zic2Ku J:238567 View
holoprosencephaly 5 Zic2Ku/Zic2Ku C3.CAnNCrl-Zic2Ku J:138862 View
holoprosencephaly 5 Zic2tm1Jaru/Zic2tm1Jaru involves: 129S4/SvJae * C57BL/6 J:60644 View
holoprosencephaly 11 Boctm1Rsk/Boc+
Cdontm1Rsk/Cdontm1Rsk
involves: 129/Sv * 129S6/SvEvTac J:171767 View
holoprosencephaly 11 Boctm1Rsk/Boctm1Rsk
Cdontm1Rsk/Cdontm1Rsk
B6.129-Boctm1Rsk Cdontm1Rsk J:171767 View
holoprosencephaly 11 Boctm1Rsk/Boctm1Rsk
Cdontm1Rsk/Cdontm1Rsk
involves: 129/Sv * 129S6/SvEvTac J:171767 View
holoprosencephaly 11 Boctm2Rsk/Boc+
Cdontm1Rsk/Cdontm1Rsk
involves: 129/Sv * 129S6/SvEvTac J:171767 View
holoprosencephaly 11 Boctm2Rsk/Boctm2Rsk
Cdontm1Rsk/Cdontm1Rsk
B6.129-Boctm2Rsk Cdontm1Rsk J:171767 View
holoprosencephaly 11 Boctm2Rsk/Boctm2Rsk
Cdontm1Rsk/Cdontm1Rsk
involves: 129/Sv * 129S6/SvEvTac J:171767 View
holoprosencephaly 11 Cdontm1Rsk/Cdontm1Rsk involves: 129/Sv * C57BL/6 J:82221 View
holoprosencephaly 11 Cdontm2Rsk/Cdontm2Rsk involves: 129/Sv * C57BL/6 J:82221 View
      chromosome 1q41-q42 deletion syndrome Trp53bp2tm1Xlu/Trp53bp2tm1Xlu B6.129S6-Trp53bp2tm1Xlu J:240594 View
chromosome 1q41-q42 deletion syndrome Trp53bp2tm1Xlu/Trp53bp2tm1Xlu C.129S6-Trp53bp2tm1Xlu J:240594 View
chromosome 1q41-q42 deletion syndrome Trp53bp2tm1Xlu/Trp53bp2tm1Xlu involves: 129S6/SvEvTac * C57BL/6J J:240594 View
holoprosencephaly NosipGt(OST138992)Lex/NosipGt(OST138992)Lex B6.129S5-NosipGt(OST138992)Lex J:245546 View
holoprosencephaly Pgap1m1Nisw/Pgap1m1Nisw involves: C57BL/6J J:187360 View
holoprosencephaly Pignm1Nisw/Pignm1Nisw involves: 129S1/SvImJ * C3H/HeJ * C57BL/6J J:187360 View
Additional
Complex
Models
     holoprosencephaly Chrdtm1Emdr/Chrdtm1Emdr
Nodaltm1Rob/Nodal+
involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ J:161524 View
holoprosencephaly Nogtm1Amc/Nogtm1Amc
Smad3tm1Xfw/Smad3+
involves: 129/Sv * 129S1/Sv J:161524 View


       
No similarity to the expected human disease phenotype was found.
        Disease Term Allelic Composition Genetic Background Reference Phenotypes
NOT Models      holoprosencephaly 4 Tgif1tm1.1Caw/Tgif1tm1.1Caw involves: C57BL/6 * FVB/N J:97642 View