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All mouse models of male reproductive system disease with phenotypic similarity to the human disease
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
  | prostate cancer | Acp3tm1Pivi/Acp3tm1Pivi | B6.Cg-Acp3tm1Pivi | J:207558 | View | |||
| prostate cancer |
Apctm1Tno/Apctm1Tno Tg(Pbsn-cre)4Prb/0 |
involves: 129S4/SvJae * C57BL/6 * C57BL/6J * DBA/2 | J:120308 | View | ||||
| prostate cancer |
Artm1Verh/Y Ptentm1Hwu/Ptentm1Hwu Tg(Pbsn-cre)4Prb/0 |
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6 * DBA/2 | J:172730 | View | ||||
| prostate cancer |
Braftm1Mmcm/Braftm1Mmcm Nkx3-1tm4(cre/ERT2)Mms/Nkx3-1+ Ptentm1Hwu/Pten+ |
involves: 129P2/OlaHsd * 129S4/SvJae * 129S6/SvEvTac * C57BL/6 | J:191327 | View | ||||
| prostate cancer |
Gt(ROSA)26Sortm1(CAG-Bmi1,-EGFP)Nki/Gt(ROSA)26Sor+ Ptentm1Mro/Pten+ Tg(Pbsn-cre)4Prb/0 |
involves: 129P2/OlaHsd * C57BL/6 * DBA/2 * FVB/N | J:184533 | View | ||||
| prostate cancer |
Gt(ROSA)26Sortm1(JAG1)Xin/Gt(ROSA)26Sor+ Ptentm1Hwu/Ptentm1Hwu Tg(Pbsn-cre)20Fwan/? |
involves: 129S4/SvJae * C57BL/6 * FVB/NCrl | J:238768 | View | ||||
| prostate cancer |
Gt(ROSA)26Sortm1(SPOP*F133V)Mrbn/Gt(ROSA)26Sor+ Ptentm2.1Ppp/Pten+ Tg(Pbsn-cre)4Prb/0 |
involves: 129S1/Sv * C57BL/6 * DBA/2 | J:239660 | View | ||||
| prostate cancer |
Gt(ROSA)26Sortm1(SPOP*F133V)Mrbn/Gt(ROSA)26Sor+ Ptentm2.1Ppp/Ptentm2.1Ppp Tg(Pbsn-cre)4Prb/0 |
involves: 129S1/Sv * C57BL/6 * DBA/2 | J:239660 | View | ||||
| prostate cancer |
Igs2tm1(CAG-Met)Zsu/Igs2+ Ptentm1Hwu/Ptentm1Hwu Tg(Pbsn-cre)4Prb/0 |
involves: 129 * C57BL/6 * DBA/2 * FVB/N | J:268934 | View | ||||
| prostate cancer |
Krastm4Tyj/Kras+ Ptentm1Hwu/Pten+ Tg(Pbsn-cre)4Prb/0 |
involves: 129S4/SvJae * C57BL/6 * DBA/2 | J:184935 | View | ||||
| prostate cancer |
Krastm4Tyj/Kras+ Ptentm1Hwu/Ptentm1Hwu Tg(Pbsn-cre)4Prb/0 |
involves: 129S4/SvJae * C57BL/6 * DBA/2 | J:184935 | View | ||||
| prostate cancer |
Nkx3-1tm1Mms/Nkx3-1+ Ptentm1Rps/Pten+ |
involves: 129S1/Sv * 129S1/SvImJ * C57BL/6J | J:75085 | View | ||||
| prostate cancer |
Nkx3-1tm1Mms/Nkx3-1tm1Mms Ptentm1Rps/Pten+ |
involves: 129S1/Sv * 129S1/SvImJ * C57BL/6J | J:75085 | View | ||||
| prostate cancer |
Ptentm1Hwu/Pten+ Tg(ARR2/Pbsn-FGF8)3Prb/0 Tg(Pbsn-cre)4Prb/0 |
involves: 129S4/SvJae * BALB/c * C57BL/6 * DBA/2 | J:106650 | View | ||||
| prostate cancer |
Ptentm1Hwu/Ptentm1Hwu Tg(CAG-MYC,-GFP*)#Rugg/0 Tg(Pbsn-cre)4Prb/0 |
involves: 129S4/SvJae * C57BL/6 * C57BL/6J * DBA/2 | J:261540 | View | ||||
| prostate cancer |
Ptentm1Hwu/Ptentm1Hwu Tg(Pbsn-cre)4Prb/0 |
involves: 129S4/SvJae * BALB/c * C57BL/6 * DBA/2 | J:93902 | View | ||||
| prostate cancer |
Ptentm1Hwu/Ptentm1Hwu Tg(Pbsn-cre)4Prb/0 |
involves: 129S4/SvJae * C57BL/6 * DBA/2 | J:172730, J:184935 | View | ||||
| prostate cancer |
Ptentm1Hwu/Ptentm1Hwu Tg(Pbsn-cre)20Fwan/? |
involves: 129S4/SvJae * C57BL/6 * FVB/NCrl | J:238768 | View | ||||
| prostate cancer |
Ptentm1Ppp/Pten+ Tg(Pbsn-TAg)15Tvd/0 |
involves: 129S1/Sv * C57BL/6 * DBA/2 | J:103408 | View | ||||
| prostate cancer |
Ptentm1Rdp/Ptentm1Rdp Terttm3Rdp/Terttm3Rdp Trp53tm1Brn/Trp53tm1Brn Tg(Pbsn-cre)4Prb/0 |
involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * DBA/2 | J:186105 | View | ||||
| prostate cancer |
Ptentm2.1Ppp/Pten+ Spry1tm1Jdli/Spry1tm1.1Jdli Spry2tm1Mrt/Spry2tm1.1Mrt Tg(Osr1-cre)4Mrt/0 |
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * FVB/N | J:192348 | View | ||||
| prostate cancer |
Ptentm2Mak/Ptentm2Mak Tg(KLK3-cre)13Saa/0 |
involves: 129P2/OlaHsd * C57BL/6 | J:214242 | View | ||||
| spermatogenic failure 19 | Cfap43em1Fzh/Cfap43em1Fzh | involves: C57BL/6 | J:258613 | View | ||||
| spermatogenic failure 19 | Cfap43em2Fzh/Cfap43em2Fzh | involves: C57BL/6 | J:258613 | View | ||||
| spermatogenic failure 20 | Cfap44em1Fzh/Cfap44em1Fzh | involves: C57BL/6 | J:258613 | View | ||||
| spermatogenic failure 24 | Cfap69em1Fzh/Cfap69em1Fzh | involves: C57BL/6J | J:288345 | View | ||||
| spermatogenic failure 24 | Cfap69tm1b(KOMP)Wtsi/Cfap69tm1b(KOMP)Wtsi | involves: C57BL/6N | J:263440 | View | ||||
| spermatogenic failure 31 | Pmfbp1em#Jfw/Pmfbp1em#Jfw | Not Specified | J:303070 | View | ||||
| spermatogenic failure 39 | Dnah17em1Qsh/Dnah17em1Qsh | involves: C57BL/6 * DBA/2J | J:285088 | View | ||||
| spermatogenic failure 40 | Cfap65em1Fzh/Cfap65em1Fzh | involves: C57BL/6 | J:292578 | View | ||||
| spermatogenic failure 46 | Dnah8em1Osb/Dnah8em1Osb | involves: C57BL/6 * DBA/2 | J:297137 | View | ||||
| spermatogenic failure 47 | Dzip1em1Yxc/Dzip1em1Yxc | Not Specified | J:333286 | View | ||||
| | azoospermia | Gopctm1.1Tno/Gopctm1.1Tno | involves: 129S4/SvJae * C57BL/6 | J:78599 | View | |||
| azoospermia | Sycp3tm1Hoog/Sycp3tm1Hoog | involves: 129P2/OlaHsd * C57BL/6 | J:60153 | View | ||||
| impotence | Adamtsl2stb/Adamtsl2stb | STOCK Adamtsl2stb + a/+ Fignfi a/J | J:346340 | View | ||||
| male infertility | Arl2bpem1Visu/Arl2bpem1Visu | involves: FVB/N | J:279003 | View | ||||
| male infertility | Armc2em1Pfr/Armc2em1Pfr | Not Specified | J:279937 | View | ||||
| male infertility |
Bscl2tm1.1Gliu/Bscl2tm1.1Gliu Tg(Fabp4-cre)1Rev/0 |
involves: 129 * 129S4/SvJaeSor | J:211072 | View | ||||
| male infertility | Cabyrem1Osb/Cabyrem1Osb | involves: C57BL/6NJcl * DBA/2NJcl | J:247126 | View | ||||
| male infertility | Ccdc146em1Cya/Ccdc146em1Cya | Not Specified | J:344445 | View | ||||
| male infertility | Cfap47em1Fzh/Y | C57BL/6-Cfap47em1Fzh | J:307391 | View | ||||
| male infertility | Cfap57em1Qsh/Cfap57em1Qsh | C57BL/6-Cfap57em1Qsh | J:333969 | View | ||||
| male infertility | Csnk2a2tm1Dcs/Csnk2a2tm1Dcs | involves: 129S6/SvEvTac * C57BL/6 | J:57312 | View | ||||
| male infertility | Cylc1em1Chnsr/Y | involves: C57BL/6JGpt | J:347872 | View | ||||
| male infertility | Cylc1em2Chnsr/Y | involves: C57BL/6JGpt | J:347872 | View | ||||
| male infertility | Dnaaf5em1Slb/Dnaaf5em1Slb | C57BL/6-Dnaaf5em1Slb | J:342770 | View | ||||
| male infertility | Pmfbp1em1Wli/Pmfbp1em1Wli | involves: C57BL/6J * DBA/2J | J:266460 | View | ||||
| male infertility | Spata16em2Osb/Spata16em2Osb | involves: 129S2/SvPas * C57BL/6 * C57BL/6NSlc * DBA/2 | J:258202 | View | ||||
| male infertility | Tcte1tm1a(KOMP)Wtsi/Tcte1tm1a(KOMP)Wtsi | C57BL/6N-Tcte1tm1a(KOMP)Wtsi | J:243766 | View | ||||
| male infertility | Tsga8em1Ohbo/Y | C57BL/6-Tsga8em1Ohbo | J:307409 | View | ||||
| male infertility | Tsga8em2Ohbo/Tsga8em2Ohbo | C57BL/6-Tsga8em2Ohbo | J:307409 | View | ||||
| male infertility due to acephalic spermatozoa | Ccdc159em1Yingz/Ccdc159em1Yingz | involves: C57BL/6NCr | J:351297 | View | ||||
| male infertility due to globozoospermia |
Hsp90b1tm1Zhli/Hsp90b1tm1.1Zhli Tg(Ddx4-cre)1Dcas/0 |
involves: 129S/SvEv * FVB | J:168319 | View | ||||
| oligoasthenoteratozoospermia | Agfg1tm1Jvd/Agfg1tm1Jvd | involves: 129P2/OlaHsd | J:102121 | View | ||||
| oligoasthenoteratozoospermia | Ccdc157em1Ymxi/Ccdc157em1Ymxi | C57BL/6-Ccdc157em1Ymxi | J:346468 | View | ||||
| oligoasthenoteratozoospermia | Cfap58em1Fzh/Cfap58em1Fzh | Not Specified | J:296991 | View | ||||
| oligoasthenoteratozoospermia | Cfap61em1Yqt/Cfap61em1Yqt | C57BL/6-Cfap61em1Yqt | J:333342 | View | ||||
| oligoasthenoteratozoospermia | Cfap70em1Chnsr/Cfap70em1Chnsr | involves: C57BL/6J | J:338031 | View | ||||
| oligoasthenoteratozoospermia | Cfap70em2Chnsr/Cfap70em2Chnsr | involves: C57BL/6J | J:338031 | View | ||||
| oligoasthenoteratozoospermia | Mlxtm1.2Rne/Mlxtm1.2Rne | involves: 129S4/SvJaeSor | J:324060 | View | ||||
| oligoasthenoteratozoospermia | Poc1bem1Xjzha/Poc1bem1Xjzha | C57BL/6J-Poc1bem1Xjzha | J:340269 | View | ||||
| oligoasthenoteratozoospermia |
Ppp4cem1Qys/Ppp4cem1Qys Tg(Stra8-icre)1Reb/0 |
involves: 129S/SvEv * C57BL/6 * FVB/NJ | J:309155 | View | ||||
| oligoasthenoteratozoospermia | Spata20Tn(pb-Act-RFP)1.1Zhu/Spata20Tn(pb-Act-RFP)1.1Zhu | FVB/NJ-Spata20Tn(pb-Act-RFP)1.1Zhu | J:262160 | View | ||||
| prostate cancer |
Ctnnb1tm1Mmt/Ctnnb1+ Igs2tm1(CAG-Met)Zsu/Igs2+ Tg(Pbsn-cre)4Prb/0 |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2 * FVB/N | J:284956 | View | ||||
| prostate cancer |
Ctnnb1tm1Mmt/Ctnnb1+ Tg(Pbsn-cre)4Prb/0 |
involves: 129X1/SvJ * C57BL/6 * DBA/2 | J:143034 | View | ||||
| prostate cancer |
Krastm1Bbd/Kras+ Tg(Pbsn-cre)4Prb/0 |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2 | J:143034 | View | ||||
| prostate cancer |
Krastm4Tyj/Kras+ Scribtm1.1Phum/Scribtm1.1Phum Tg(Pbsn-cre)20Fwan/0 |
involves: 129S4/SvJae * FVB/NCrl | J:178461 | View | ||||
| prostate cancer | Msmbtm1Xuan/Msmbtm1Xuan | either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * CD-1) | J:96884 | View | ||||
| prostate cancer | Nkx3-1tm1Hha/Nkx3-1+ | involves: 129S4/SvJae * C57BL/6 | J:63764 | View | ||||
| prostate cancer | Nkx3-1tm1Hha/Nkx3-1tm1Hha | involves: 129S4/SvJae * C57BL/6 | J:63764 | View | ||||
| prostate cancer | Nkx3-1tm1Mms/Nkx3-1+ | either: (involves: 129S1/Sv * 129S1/SvImJ) or (involves: 129S1/Sv * 129S1/SvImJ * C57BL/6J) | J:54465 | View | ||||
| prostate cancer | Nkx3-1tm1Mms/Nkx3-1tm1Mms | either: (involves: 129S1/Sv * 129S1/SvImJ) or (involves: 129S1/Sv * 129S1/SvImJ * C57BL/6J) | J:54465 | View | ||||
| prostate cancer |
Tgfbr2tm1.2Hlm/Tgfbr2tm1.2Hlm Tg(Col1a2-cre/ERT,-ALPP)7Cpd/0 |
involves: 129S6/SvEvTac * C57BL/6 * DBA/2 | J:204736 | View | ||||
| Sertoli cell-only syndrome | Dmc1Mei11/Dmc1Mei11 | involves: 129S4/SvJae * C57BL/6J | J:60747 | View | ||||
| Sertoli cell-only syndrome | Mast4em1Sjkm/Mast4em1Sjkm | C57BL/6J-Mast4em1Sjkm | J:340701 | View | ||||
| Sertoli cell-only syndrome | Nupr1tm1Jlio/Nupr1tm1Jlio | involves: 129S1/Sv * 129X1/SvJ | J:140899 | View | ||||
| spermatogenic failure | Ccdc34em1Fzg/Ccdc34em1Fzg | C57BL/6-Ccdc34em1Fzg | J:333018 | View | ||||
| spermatogenic failure | Dnah10em1Yxc/Dnah10em1Yxc | involves: C57BL/6 | J:311550 | View | ||||
| spermatogenic failure | Dnah10em2Yxc/Dnah10em2Yxc | involves: C57BL/6 | J:311550 | View | ||||
| | prostate cancer |
Artm1(AR)Dmr/Y Tg(TRAMP)8247Ng/0 |
involves: 129S1/Sv * C57BL/6 | J:108849 | View | |||
| prostate cancer |
Artm2(AR)Dmr/Y Tg(TRAMP)8247Ng/0 |
involves: 129S1/Sv * C57BL/6 | J:108849 | View | ||||
| prostate cancer |
Artm3(AR)Dmr/Y Tg(TRAMP)8247Ng/0 |
involves: 129S1/Sv * C57BL/6 | J:108849 | View | ||||
| prostate cancer |
Brca2tm1Brn/Brca2tm1Brn Trp53tm1Brn/Trp53tm1Brn Tg(Pbsn-cre)4Prb/0 |
involves: 129P2/OlaHsd * C57BL/6 * DBA/2 | J:161511 | View | ||||
| prostate cancer |
Cdkn2atm1Rdp/Cdkn2atm1Rdp Tg(tetO-BRAF*V600E)29Lc/0 Tg(Tyr-rtTA)37Lc/0 |
involves: 129/Sv * C57BL/6J * SJL | J:144358 | View | ||||
| Transgenes and Other Mutations | male infertility | Rr401em1Yushi/Rr401em1Yushi | Not Specified | J:334319 | View | |||
| prostate adenocarcinoma | Tg(Pbsn-Tag)12T10Rjm/0 | involves: CD-1 | J:68483 | View | ||||
| prostate cancer | Tg(ARR2/Pbsn-MYC)7Key/? | involves: FVB/N | J:85480 | View | ||||
| prostate cancer | Tg(C3-1-TAg)cJeg/0 | involves: FVB/N | J:52786 | View | ||||
| prostate cancer |
Tg(CAG-SAC/EGFP)35Rang/0 Tg(TRAMP)8247Ng/0 |
involves: C3H * C57BL/6 | J:125633 | View | ||||
| prostate cancer | Tg(Ggamma-T)15Cps/0 | involves: C57BL/6J * CBA/J | J:38778 | View | ||||
| prostate cancer | Tg(Ggamma-T)15Cps/Tg(Ggamma-T)15Cps | involves: C57BL/6J * CBA/J | J:38778 | View | ||||
| prostate cancer |
Tg(H-2K1-Lrp5/Fkbp1a,-luc*)#Dmps/0 Tg(Pbsn-Fgfr1/Fkbp1a)#aDmsp/0 |
involves: FVB/N | J:206727 | View | ||||
| prostate cancer | Tg(Msmb-TAg)183-2Xuan/0 | involves: C57BL/6 * CBA | J:80313 | View | ||||
| prostate cancer | Tg(Msmb-TAg)186-3Xuan/0 | involves: C57BL/6 * CBA | J:80313 | View | ||||
| prostate cancer | Tg(Pbsn-Ar*E231G)7353Ng/0 | involves: FVB/N | J:96117 | View | ||||
| prostate cancer | Tg(Pbsn-ERG*)1Vv/0 | involves: 129S1/SvImJ * C57BL/6J * CBA | J:222916 | View | ||||
| prostate cancer | Tg(Pbsn-Fgfr1/Fkbp1a)#aDmsp/0 | FVB-Tg(Pbsn-Fgfr1/Fkbp1a)#aDmsp | J:130340 | View | ||||
| prostate cancer |
Tg(Pbsn-IGF1*)5305Ng/0 Tg(TRAMP)8247Ng/0 |
involves: C57BL/6 * FVB/N | J:144539 | View | ||||
| prostate cancer | Tg(Pbsn-MYC)6Key/? | involves: FVB | J:85480 | View | ||||
| prostate cancer | Tg(Pbsn-MYC)#Tt/? | involves: C57BL/6J | J:205395 | View | ||||
| prostate cancer | Tg(Pbsn-Tag)12T7fRjm/0 | involves: CD-1 | J:48623 | View | ||||
| prostate cancer | Tg(Pbsn-TAg)15Tvd/0 | involves: C57BL/6 * DBA/2 | J:103408 | View | ||||
| prostate cancer | Tg(TRAMP)8247Ng/0 | involves: C57BL/6 | J:65303 | View | ||||
| Additional Complex Models | prostate adenocarcinoma |
Gt(ROSA)26Sortm1(CAG-AR)Zsu/Gt(ROSA)26Sor+ Tg(Osr1-cre)4Mrt/0 |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N | J:234601 | View | |||
| prostate adenocarcinoma |
Gt(ROSA)26Sortm1(CAG-AR)Zsu/Gt(ROSA)26Sortm1(CAG-AR)Zsu Tg(Osr1-cre)4Mrt/0 |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N | J:234601 | View | ||||
| prostate cancer |
Col1a1tm1(tetO-YAP1*)Fcam/Col1a1+ Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy/Gt(ROSA)26Sor+ Tg(Pbsn-cre)4Prb/0 |
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6 * DBA/2 | J:222916 | View | ||||
| prostate neuroendocrine neoplasm |
Gt(ROSA)26Sortm1(CAG-MYCN,-luc)Jhsc/Gt(ROSA)26Sor+ Ptentm2.1Ppp/Ptentm2.1Ppp Rb1tm2Brn/Rb1+ Tg(Pbsn-cre)4Prb/0 |
involves: 129 * 129S1/Sv * 129S6/SvEvTac * C57BL/6 * DBA/2 | J:307910 | View | ||||
| prostate neuroendocrine neoplasm |
Gt(ROSA)26Sortm1(CAG-MYCN,-luc)Jhsc/Gt(ROSA)26Sor+ Ptentm2.1Ppp/Ptentm2.1Ppp Rb1tm2Brn/Rb1tm2Brn Tg(Pbsn-cre)4Prb/0 |
involves: 129 * 129S1/Sv * 129S6/SvEvTac * C57BL/6 * DBA/2 | J:307910 | View | ||||