Excel File Text File All mouse models of thyroid gland disease with phenotypic similarity to the human disease
        Disease Term Allelic Composition Genetic Background Reference Phenotypes
      Bamforth-Lazarus syndrome Foxe1tm1Rdl/Foxe1tm1Rdl involves: 129S1/Sv * 129X1/SvJ * C57BL/6 J:48970, J:93410 View
congenital hypothyroidism Duox2thyd/Duox2thyd B6(129)-Duox2thyd/J J:121821 View
congenital hypothyroidism Pax8tm1(cre)Mbu/Pax8tm1(cre)Mbu involves: 129P2/OlaHsd * C3H/He * C57BL/6 J:80208 View
congenital hypothyroidism Pax8tm1Pgr/Pax8tm1Pgr either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6) J:47310, J:116236 View
congenital hypothyroidism Pax8tm1Pgr/Pax8tm1Pgr involves: 129S1/Sv * 129X1/SvJ J:130062 View
congenital hypothyroidism TpoR479C/TpoR479C involves: ICR J:112930 View
papillary thyroid carcinoma Braftm1Cpri/Braftm1Cpri
Tg(TPO-cre)1Shk/0		 involves: 129P2/OlaHsd * FVB/NCr J:168249 View
papillary thyroid carcinoma Braftm1Mmcm/Braf+
Tg(Tg-cre/ERT2)#Mmcm/0		 involves: 129P2/OlaHsd J:172205 View
thyroid hormone resistance syndrome Thrbtm1.1Syc/Thrb+ involves: 129S6/SvEvTac * FVB/N * NIH Black Swiss J:65885 View
thyroid hormone resistance syndrome Thrbtm1.1Syc/Thrbtm1.1Syc involves: 129S6/SvEvTac * C57BL/6J * NIH Black Swiss J:124153 View
thyroid hormone resistance syndrome Thrbtm1.1Syc/Thrbtm1.1Syc involves: 129S6/SvEvTac * FVB/N * NIH Black Swiss J:65885 View
thyroid hormone resistance syndrome Thrbtm1.1Syc/Thrbtm1.1Syc involves: 129S6/SvEvTac * NIH Black Swiss J:114325 View
thyroid hormone resistance syndrome Thrbtm1Df/Thrbtm1Df involves: 129S1/Sv * C57BL/6J J:34421, J:63101 View
thyroid hormone resistance syndrome Thrbtm2Few/Thrb+ involves: 129X1/SvJ * C57BL/6 J:77623 View
thyroid hormone resistance syndrome Thrbtm2Few/Thrbtm2Few involves: 129X1/SvJ * C57BL/6 J:77623 View
thyroid hormone resistance syndrome Thrbtm3Few/Thrbtm3Few involves: 129 * C57BL/6 J:85158 View
thyroid hormone resistance syndrome Thrbtm6.1Few/Thrb+ involves: 129 * C57BL/6 J:150008 View
thyroid hormone resistance syndrome Thrbtm6.1Few/Thrbtm6.1Few involves: 129 * C57BL/6 J:150008 View
      congenital hypothyroidism Foxe1tm1Rdl/Foxe1tm1Rdl involves: 129S1/Sv * 129X1/SvJ * C57BL/6 J:48970 View
congenital hypothyroidism Runx2tm1Kish/Runx2+ involves: 129P2/OlaHsd * C57BL/6 J:162258 View
congenital hypothyroidism Slc26a7tm1Sole/Slc26a7tm1Sole involves: 129 J:325346 View
congenital hypothyroidism Tgcog/Tgcog involves: AKR/J * C57BL/6By J:8567 View
congenital hypothyroidism Trhrtm1Bau/Trhrtm1Bau involves: 129S1/Sv * 129X1/SvJ * C57BL/6 J:220755 View
congenital hypothyroidism Tshrhyt-3J/Tshrhyt-3J CByJ;CXB10-Tshrhyt-3J/GrsrJ J:210510 View
congenital hypothyroidism Tshrhyt-3J/Tshrhyt-3J CXB10/HiAJ-Tshrhyt-3J/GrsrJ J:210510 View
congenital hypothyroidism Tshrhyt/Tshrhyt CBy.RF-Tshrhyt/J J:110962, J:130062 View
congenital hypothyroidism Tshrtm1Rmar/Tshrtm1Rmar involves: 129S1/Sv * C57BL/6J J:80513 View
familial medullary thyroid carcinoma Prlrtm1Cnp/Prlrtm1Cnp involves: 129/Sv * 129P2/OlaHsd J:101609 View
follicular thyroid carcinoma Prkar1atm1.2Lsk/Prkar1atm1.2Lsk
Ptentm1.1Mwst/Ptentm1.1Mwst
Tg(TPO-cre)1Shk/0		 involves: 129S1/Sv * 129X1/SvJ * FVB/NCr J:241066 View
follicular thyroid carcinoma Prkar1atm1.2Lsk/Prkar1atm1.2Lsk
Tg(TPO-cre)1Shk/0		 involves: 129S1/Sv * 129X1/SvJ * FVB/NCr J:241066 View
follicular thyroid carcinoma Ptentm1Hwu/Pten+
Tg(Nkx2-1-cre)2Sand/0		 B6.Cg-Ptentm1Hwu Tg(Nkx2-1-cre)2Sand J:197590 View
follicular thyroid carcinoma Ptentm2.1Ppp/Ptentm2.1Ppp
Tg(TPO-cre)1Shk/0		 129S1.Cg-Ptentm2.1Ppp Tg(TPO-cre)1Shk J:165293 View
follicular thyroid carcinoma Thrbtm1.1Syc/Thrbtm1.1Syc involves: 129S1/Sv * 129S6/SvEvTac * C57BL/6 * C57BL/6J J:92629 View
follicular thyroid carcinoma Thrbtm1Df/Thrbtm1.1Syc involves: 129S1/Sv * 129S6/SvEvTac * C57BL/6 * C57BL/6J J:92629 View
thyroid hormone resistance syndrome Ncoa1tm1Bwo/Ncoa1tm1Bwo involves: 129/Sv * C57BL/6 J:54182 View
thyroid hormone resistance syndrome Thraem1Ffla/Thra+ C57BL/6-Thraem1Ffla J:268664 View
thyroid hormone resistance syndrome Thraem2Ffla/Thra+ C57BL/6-Thraem2Ffla J:268664 View
Transgenes and
Other Mutations		     follicular thyroid carcinoma Tg(TG-NRAS*Q61K)#Msnt/0 Not Specified J:210016 View
papillary thyroid carcinoma Tg(tetO-BRAF*V600E)26Jaf/0
Tg(TG-rtTA)30Jaf/0		 involves: FVB/N J:184420 View
papillary thyroid carcinoma Tg(TG-BRAF*V600E)2Jaf/0 FVB/N-Tg(TG-BRAF*V600E)2Jaf J:98550, J:195921 View
papillary thyroid carcinoma Tg(TG-RET/CCDC6)42Cled/0 involves: FVB/N J:93679, J:55883 View
papillary thyroid carcinoma Tg(TG-RET/NCOA4)3209Rstn/0 involves: C57BL/6 J:51366 View
papillary thyroid carcinoma Tg(TG-TPR/NTRK1)5215Rstn/0 involves: C3H * C57BL/6 J:67120 View
thyroid cancer Tg(TG-TPR/NTRK1)#Rstn/0 involves: 129S4/SvJaeSor * C3H * C57BL/6 * C57BL/6J J:210015 View
thyroid hormone resistance syndrome Tg(ACTB-THRB*)DSyc/0 Not Specified J:134187 View
Additional
Complex
Models		     thyroid cancer Hrastm1Jaf/Hrastm1Jaf
Nf2tm2Gth/Nf2tm2Gth
Tg(TPO-cre)1Shk/0		 involves: 129P2/OlaHsd * 129S6/SvEvTac * Black Swiss * C57BL/6 * FVB/NCr J:231492 View
thyroid cancer Hrastm1Jaf/Hrastm1Jaf
Ptentm2.1Ppp/Ptentm2.1Ppp
Tg(TPO-cre)1Shk/0		 involves: 129S1/Sv * 129S6/SvEvTac * FVB/NCr J:231492 View
thyroid cancer Hrastm1Jaf/Hrastm1Jaf
Trp53tm1Brn/Trp53tm1Brn
Tg(TPO-cre)1Shk/0		 involves: 129P2/OlaHsd * 129S6/SvEvTac * Black Swiss * C57BL/6 * FVB/NCr J:231492 View
thyroid gland carcinoma Ptentm1Hwu/Ptentm1Hwu
Tg(CAG-EGFP,-PAX8/PPARG)1Rkoe/0
Tg(TPO-cre)1Shk/0		 involves: 129S4/SvJae * FVB/NCr * FVB/NJ J:177181 View
thyroid gland carcinoma Ptentm2.1Ppp/Ptentm2.1Ppp
Trp53tm1Brn/Trp53tm1Brn
Tg(TPO-cre)1Shk/0		 129.Cg-Tg(TPO-cre)1Shk Trp53tm1Brn Ptentm2.1Ppp J:211100 View

       
No similarity to the expected human disease phenotype was found.
        Disease Term Allelic Composition Genetic Background Reference Phenotypes
NOT Models      familial medullary thyroid carcinoma Rettm2.1Cos/Ret+ involves: 129S1/Sv * C57BL/6J * FVB/N J:60659 View
familial medullary thyroid carcinoma Rettm2.1Cos/Rettm2.1Cos involves: 129S1/Sv * C57BL/6J * FVB/N J:60659 View