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Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
![]() ![]() | aortic aneurysm |
Agtr2tm1Tin/Y Efemp2tm1.1Hiya/Efemp2tm1.2Hiya Tg(Tagln-cre)1Her/0 |
involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * SJL | J:213282 | View | |||
aortic aneurysm |
Efemp2tm1.1Hiya/Efemp2tm1.2Hiya Tg(Tagln-cre)1Her/0 |
involves: 129S6/SvEvTac * C57BL/6 * SJL | J:213282 | View | ||||
Marfan syndrome | Fbn1tm1Hcd/Fbn1+ | involves: 129S1/Sv * 129X1/SvJ * C57BL/6J | J:91349, J:94428 | View | ||||
Marfan syndrome | Fbn1tm1Lper/Fbn1+ | involves: 129/Sv * C57BL/6 * CD-1 | J:167276 | View | ||||
Marfan syndrome | Fbn1tm1Lper/Fbn1+ | involves: 129/Sv * CD-1 | J:167276 | View | ||||
Marfan syndrome | Fbn1tm1Rmz/Fbn1tm1Rmz | involves: 129S4/SvJae * C57BL/6J | J:43199 | View | ||||
Marfan syndrome | Fbn1tm2Rmz/Fbn1tm2Rmz | involves: 129S1/Sv * 129X1/SvJ | J:54081 | View | ||||
Marfan syndrome | Fbn1tm3Rmz/Fbn1tm3Rmz | Not Specified | J:110586 | View | ||||
Marfan syndrome | Fbn1Tsk/Fbn1+ | B6.Cg-Fbn1Tsk | J:30961 | View | ||||
Marfan syndrome | Fbn1Tsk/Fbn1+ | B10.D2/(58N)Sn | J:21512 | View | ||||
supravalvular aortic stenosis | Elntm1Dyl/Eln+ | B6.129-Elntm1Dyl | J:86535 | View | ||||
supravalvular aortic stenosis | Elntm1Dyl/Eln+ | involves: 129S1/Sv * 129X1/SvJ * C57BL/6J | J:51109 | View | ||||
![]() | aortic aneurysm | Atp7aMo-blo/Atp7a+ | Not Specified | J:5516 | View | |||
aortic aneurysm | Atp7aMo-blo/Y | Not Specified | J:5516, J:15796 | View | ||||
aortic aneurysm | Klf15tm1Jain/Klf15tm1Jain | B6.129X1-Klf15tm1Jain | J:167880 | View | ||||
aortic dissection |
Best3tm1.1Zhoj/Best3tm1.1Zhoj Tg(Tagln-cre)1Her/0 |
involves: C57BL/6 * SJL | J:338981 | View | ||||
aortic valve disease | Adamts19tm4a(EUCOMM)Wtsi/Adamts19tm4a(EUCOMM)Wtsi | C57BL/6N-Adamts19tm4a(EUCOMM)Wtsi | J:287334 | View | ||||
aortic valve disease | Adamts19tm4b(EUCOMM)Wtsi/Adamts19tm4b(EUCOMM)Wtsi | B6N(Cg)-Adamts19tm4b(EUCOMM)Wtsi | J:287334 | View | ||||
aortic valve disease | Egfrwa2/Egfrwa2 | involves: C57BL/6 | J:241813 | View | ||||
aortic valve disease | Egfrwa2/Egfrwa2 | STOCK Egfrwa2 | J:60750 | View | ||||
aortic valve disease | Elntm1Dyl/Eln+ | involves: 129S1/Sv * 129X1/SvJ * C57BL/6 | J:184494 | View | ||||
aortic valve disease | Hey2tm1Kkb/Hey2tm1Kkb | involves: 129S7/SvEvBrd * C57BL/6 | J:216895 | View | ||||
aortic valve disease | Nos3tm1Unc/Nos3tm1Unc | B6.129P2-Nos3tm1Unc/J | J:103340 | View | ||||
aortic valve disease | Rbpjtm1Kyo/Rbpj+ | involves: 129S2/SvPas * CD-1 | J:187551 | View | ||||
aortic valve stenosis | Tnftm2Gkl/Tnf+ | involves: 129S/SvEv * C57BL/6J | J:264147 | View | ||||
Marfan syndrome | Mus81tm1Esse/Mus81tm1Esse | involves: 129P2/OlaHsd * C57BL/6 | J:133703 | View | ||||
Additional Complex Models | aortic valve disease |
Apobtm2Sgy/Apobtm2Sgy Ldlrtm1Her/Ldlrtm1Her Tg(Ins-Igf2)1Fbos/? |
involves: 129S7/SvEvBrd * C57BL/6 * C57BL/6J * SJL | J:227165 | View |
No similarity to the expected human disease phenotype was found.
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Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
NOT Models | Marfan syndrome | Fbn1tm3.2Lysa/Fbn1+ | Not Specified | J:181493 | View | |||
Marfan syndrome | Fbn1tm3.2Lysa/Fbn1tm3.2Lysa | Not Specified | J:181493 | View |