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All mouse models of pituitary gland disease with phenotypic similarity to the human disease
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Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
adrenocorticotropic hormone deficiency | Tbx19tm1Jdr/Tbx19tm1Jdr | either: (involves: 129/Sv) or (involves: BALB/c) | J:82561 | View | ||||
hypopituitarism | Prop1df/Prop1df | involves: C57BL/6J | J:94409 | View | ||||
hypopituitarism | Prop1df/Prop1df | STOCK Prop1df | J:12169, J:5900, J:6340, J:7211, J:36967 | View | ||||
isolated growth hormone deficiency type II | GhSma1/Gh+ | C3HeB/FeJ-GhSma1 | J:89518 | View | ||||
isolated growth hormone deficiency type II | GhSma1/GhSma1 | C3HeB/FeJ-GhSma1 | J:89518 | View | ||||
growth hormone secreting pituitary adenoma | Men1tm1Zqw/Men1+ | involves: 129/Sv * 129P2/OlaHsd | J:85302 | View | ||||
hypopituitarism | Hesx1tm1Icar/Hesx1tm1Icar | involves: 129P2/OlaHsd * C57BL/6 | J:47920 | View | ||||
hypopituitarism | Lhx3tm1.1Sjr/Lhx3tm1.1Sjr | involves: 129S/SvEv * C57BL/6J * FVB/N | J:169035 | View | ||||
hypopituitarism | Smpd3tm1Wst/Smpd3tm1Wst | involves: 129S1/Sv | J:97284 | View | ||||
isolated growth hormone deficiency type IA | Ghrhtm1Salv/Ghrhtm1Salv | involves: 129 * C57BL/6 | J:91828 | View | ||||
pituitary-dependent Cushing's disease | Scg5tm1Led/Scg5tm1Led | either: 129S6/SvEvTac or (involves: 129S6/SvEvTac * FVB) or (involves: 129S6/SvEvTac * C57BL/6) | J:77510 | View | ||||
prolactinoma | Men1tm1Zqw/Men1+ | involves: 129/Sv * 129P2/OlaHsd | J:85302 | View | ||||
Transgenes and Other Mutations | acromegaly | Tg(Mt1-GH1)#Jjk/0 | C57BL/6J-Tg(Mt1-GH1)#Jjk | J:157146 | View | |||
ACTH-secreting pituitary adenoma | Tg(PyLT)1Vb/0 | Not Specified | J:55528 | View | ||||
prolactinoma | Tg(Prl-EGFR)#Sme/0 | Not Specified | J:219654 | View | ||||
Additional Complex Models | isolated growth hormone deficiency |
Gt(ROSA)26Sortm1(HBEGF)Awai/Gt(ROSA)26Sor+ Tg(Gh1-cre)bKnmn/0 |
involves: C57BL/6 * FVB/N | J:169459 | View |