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All mouse models of paraplegia with phenotypic similarity to the human disease
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
  | hereditary spastic paraplegia 2 |
Plp1tm1c(EUCOMM)Wtsi/Y Cnptm1(cre)Kan/Cnp+ |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6N | J:245100 | View | |||
| hereditary spastic paraplegia 2 | Plp1tm1Kan/Y | involves: 129S1/Sv * 129X1/SvJ | J:48031, J:245100 | View | ||||
| hereditary spastic paraplegia 4 | SpastM1Gri/SpastM1Gri | B6.C-SpastM1Gri | J:148877 | View | ||||
| hereditary spastic paraplegia 4 | Spasttm1.1Evre/Spasttm1.1Evre | C57BL/6-Spasttm1.1Evre | J:253467 | View | ||||
| hereditary spastic paraplegia 4 | Spasttm1.1Jme/Spasttm1.1Jme | involves: C57BL/6J | J:117740 | View | ||||
| hereditary spastic paraplegia 7 | Spg7tm1Eir/Spg7tm1Eir | either: 129/Sv-Spg7tm1Eir or (involves: 129/Sv * C57BL/6) | J:87616 | View | ||||
| hereditary spastic paraplegia 11 | Spg11Gt(EUCE0085f05)Hmgu/Spg11Gt(EUCE0085f05)Hmgu | involves: 129P2/OlaHsd * C57BL/6 | J:228803 | View | ||||
| hereditary spastic paraplegia 13 | Hspd1Gt(OST171441)Lex/Hspd1+ | B6.129S5-Hspd1Gt(OST171441)Lex | J:197946 | View | ||||
| hereditary spastic paraplegia 15 | Zfyve26tm1.1Cahb/Zfyve26tm1.1Cahb | involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6 | J:223127 | View | ||||
| hereditary spastic paraplegia 30 | Kif1algdg-2J/Kif1algdg-2J | C57BL/6J-Kif1algdg-2J/CxJ | J:229662 | View | ||||
| hereditary spastic paraplegia 30 | Kif1algdg/Kif1algdg | C3.Cg-Kif1algdg/GrsrJ | J:229662 | View | ||||
| hereditary spastic paraplegia 31 | Reep1Gt(OST398247)Tigm/Reep1Gt(OST398247)Tigm | B6J.Cg-Reep1Gt(OST398247)Tigm | J:239250 | View | ||||
| hereditary spastic paraplegia 35 | Fa2htm1.1Hama/Fa2htm1.1Hama | involves: 129 * C57BL/6 | J:171655 | View | ||||
| hereditary spastic paraplegia 48 | Ap5z1tm1(KOMP)Wtsi/Ap5z1tm1(KOMP)Wtsi | involves: 129 * C57BL/6N | J:283611 | View | ||||
| hereditary spastic paraplegia 54 | Ddhd2tm1Crv/Ddhd2tm1Crv | involves: C57BL/6 | J:216446 | View | ||||
| hereditary spastic paraplegia 80 | Ubap1em1Yta/Ubap1+ | involves: C57BL/6 * C57BL/6N * DBA/2 | J:332139 | View | ||||
| MASA syndrome | L1camtm1Mtei/Y | either: (involves: 129/Sv * C57BL/6J) or (involves: 129/Sv * 129S/SvEv) | J:43838 | View | ||||
| Mast syndrome | Spg21tm1Mchan/Spg21tm1Mchan | Not Specified | J:302256 | View | ||||
| Troyer syndrome | Sparttm1.1Xen/Sparttm1.1Xen | involves: C57BL/6J | J:185987 | View | ||||
| | hereditary spastic paraplegia | Borcs7Q87X/Borcs7Q87X | involves: 129S6/SvEvTac * C57BL/6 * DBA/2 | J:271219 | View | |||
| Additional Complex Models | hereditary spastic paraplegia |
Atl1tm1.1Cbla/Atl1tm1.1Cbla Reep1Gt(OST398247)Tigm/Reep1Gt(OST398247)Tigm |
B6.Cg-Reep1Gt(OST398247)Tigm Atl1tm1.1Cbla | J:334532 | View | |||
| hereditary spastic paraplegia 4 | Gt(ROSA)26Sortm1.1(CAG-SPAST*C448Y)Baas/Gt(ROSA)26Sor+ | involves: C57BL/6N | J:273408 | View | ||||
| hereditary spastic paraplegia 4 | Gt(ROSA)26Sortm1.1(CAG-SPAST*C448Y)Baas/Gt(ROSA)26Sortm1.1(CAG-SPAST*C448Y)Baas | involves: C57BL/6N | J:273408 | View | ||||
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No similarity to the expected human disease phenotype was found.
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
| NOT Models | hereditary spastic paraplegia 2 |
Plp1tm1c(EUCOMM)Wtsi/Y Neurod6tm1(cre)Kan/Neurod6+ |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6N | J:245100 | View | |||
| hereditary spastic paraplegia 8 | Washc5tm1.2Cbee/Washc5+ | involves: C57BL/6 | J:266630 | View | ||||