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All mouse models of severe combined immunodeficiency with phenotypic similarity to the human disease
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Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
adenosine deaminase deficiency |
Adatm1Mw/Adatm1Mw Tg(PLADA)4118Rkmb/0 |
involves: 129S7/SvEvBrd * C57BL/6 | J:73418 | View | ||||
MHC class II deficiency | Ciitatm1Ccum/Ciitatm1Ccum | involves: 129S2/SvPas * C57BL/6J | J:31601 | View | ||||
MHC class II deficiency | Ciitatm2Wrth/Ciitatm2Wrth | involves: 129P2/OlaHsd * C57BL/6 | J:92170 | View | ||||
Omenn syndrome | Rag2tm1Avla/Rag2tm1Avla | involves: 129/Sv * C57BL/6 | J:122108 | View | ||||
severe combined immunodeficiency with sensitivity to ionizing radiation | Dclre1ctm1Jsek/Dclre1ctm1Jsek | involves: 129S1/Sv * 129X1/SvJ * C57BL/6 | J:147864 | View | ||||
severe combined immunodeficiency with sensitivity to ionizing radiation | Dclre1ctm2Mcow/Dclre1ctm2Mcow | involves: 129/Sv * C57BL/6 | J:96535 | View | ||||
severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-negative, Nk cell-positive | Rag2tm1Fwa/Rag2tm1Fwa | involves: 129S/SvEv * MF1 | J:1935 | View | ||||
T-cell immunodeficiency, congenital alopecia, and nail dystrophy | Foxn1nu-2J/Foxn1nu-2J | B6(SJL)-Foxn1nu-2J/GrsrJ | J:222308 | View | ||||
T-cell immunodeficiency, congenital alopecia, and nail dystrophy | Foxn1nu-Y/Foxn1nu-Y | 101/HY-Foxn1nu-Y | J:29022 | View | ||||
T-cell immunodeficiency, congenital alopecia, and nail dystrophy | Foxn1nu/Foxn1nu | Not Specified | J:11959 | View | ||||
T-cell immunodeficiency, congenital alopecia, and nail dystrophy | Foxn1tm1Tbo/Foxn1tm1Tbo | involves: 129S1/Sv | J:33796 | View | ||||
severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-negative, Nk cell-positive | Prkdcscid/Prkdcscid | C.BKa-Prkdcscid | J:6958 | View | ||||
severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-positive, Nk cell-positive | Coro1akoy/Coro1akoy | C57BL/6-Coro1akoy | J:141431 | View | ||||
severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-positive, Nk cell-positive | Coro1aptcd/Coro1aptcd | B6.CTS-Coro1aptcd | J:141431 | View | ||||
severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-positive, Nk cell-positive | Coro1aptcd/Coro1atm1Achn | B6.Cg-Coro1aptcd Coro1atm1Achn | J:141431 | View | ||||
severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-positive, Nk cell-positive | Coro1atm1Achn/Coro1atm1Achn | B6.129X1-Coro1atm1Achn | J:141431 | View | ||||
severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-positive, Nk cell-positive | Jak3tm1Ljb/Jak3tm1Ljb | involves: 129S4/SvJae | J:64861 | View | ||||
severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-positive, Nk cell-positive | Jak3tm1Tks/Jak3tm1Tks | involves: 129P2/OlaHsd * C57BL/6 | J:31231 | View |
No similarity to the expected human disease phenotype was found.
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Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
NOT Models | immunodeficiency 24 | Ctps1em1Slat/Ctps1em1Slat | C57BL/6J-Ctps1em1Slat | J:348981 | View | |||
Omenn syndrome | Rag1tm1Jsek/Rag1tm1Jsek | involves: 129S6/SvEvTac | J:146912 | View | ||||
X-linked severe combined immunodeficiency | Il2rgtm1Cgn/Il2rgtm1Cgn | involves: 129 * CB20 | J:22521 | View | ||||
X-linked severe combined immunodeficiency | Il2rgtm1Cgn/Y | involves: 129 * CB20 | J:22521 | View | ||||
X-linked severe combined immunodeficiency | Il2rgtm1Sug/Y | either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129S6/SvEvTac * C57BL/6) | J:31167 | View |