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All mouse models of combined T cell and B cell immunodeficiency with phenotypic similarity to the human disease
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Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
DNA ligase IV deficiency | Lig4tiny/Lig4tiny | C57BL/6-Lig4tiny | J:122725 | View | ||||
DNA ligase IV deficiency | Lig4tm2.1Fwa/Lig4tm2.1Fwa | involves: 129S6/SvEvTac | J:157574 | View | ||||
immunodeficiency 15A | Ikbkbem1Macc/Ikbkb+ | involves: C57BL/6NCrl | J:290616 | View | ||||
immunodeficiency 15A | Ikbkbem1Macc/Ikbkbem1Macc | involves: C57BL/6NCrl | J:290616 | View | ||||
leukocyte adhesion deficiency 1 | Itgb2tm1Bay/Itgb2tm1Bay | involves: 129S7/SvEvBrd | J:13599 | View | ||||
leukocyte adhesion deficiency 1 | Itgb2tm1Bay/Itgb2tm1Bay | involves: 129S7/SvEvBrd * C57BL/6J | J:13599 | View | ||||
leukocyte adhesion deficiency 1 | Itgb2tm2Bay/Itgb2tm2Bay | involves: 129S7/SvEvBrd * C57BL/6J | J:48542 | View | ||||
leukocyte adhesion deficiency 3 | Fermt3tm1Ref/Fermt3tm1Ref | involves: 129S1/Sv * 129X1/SvJ | J:146783 | View | ||||
purine nucleoside phosphorylase deficiency | Pnpe/Pnpe | C57BL/6J-Pnpe | J:39328 | View | ||||
purine nucleoside phosphorylase deficiency | Pnpe/Pnpe | involves: C3H/HeHa * C57BL/6J | J:23354 | View | ||||
purine nucleoside phosphorylase deficiency | Pnpf/Pnpf | C57BL/6J-Pnpf | J:39328 | View | ||||
purine nucleoside phosphorylase deficiency | Pnpf/Pnpf | involves: C3H/HeHa * C57BL/6J | J:23354 | View | ||||
purine nucleoside phosphorylase deficiency | Pnpg/Pnpg | involves: C57BL/6 * DBA/2J | J:39328 | View | ||||
leukocyte adhesion deficiency 3 | Rasgrp2tm1Amg/Rasgrp2tm1Amg | Not Specified | J:122618 | View |
No similarity to the expected human disease phenotype was found.
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Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
NOT Models | combined T cell and B cell immunodeficiency | Il2rgtm1Cgn/Il2rgtm1Cgn | involves: 129 * CB20 | J:22521 | View | |||
combined T cell and B cell immunodeficiency | Il2rgtm1Cgn/Y | involves: 129 * CB20 | J:22521 | View | ||||
combined T cell and B cell immunodeficiency | Il2rgtm1Sug/Y | either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129S6/SvEvTac * C57BL/6) | J:31167 | View |