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All mouse models of cerebrovascular disease with phenotypic similarity to the human disease
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
  | arteriovenous malformations of the brain | Engtm2.1Hma/Engtm2.1Hma | involves: 129P2/OlaHsd | J:196810 | View | |||
| arteriovenous malformations of the brain |
Krastm4Tyj/Kras+ Tg(Cdh5-cre/ERT2)1Rha/0 |
involves: 129S4/SvJae * FVB | J:312482 | View | ||||
| arteriovenous malformations of the brain |
Krastm4Tyj/Kras+ Tg(Slco1c1-icre/ERT2)1Mash/0 |
involves: 129S4/SvJae * C57BL/6 * DBA/2 * FVB | J:312482 | View | ||||
| cerebral cavernous malformation |
Krit1tm1Kwhi/Krit1tm1Kwhi Tg(Cdh5-cre/ERT2)1Rha/0 |
involves: 129S6/SvEvTac * C57BL/6NCrl | J:232707, J:250906 | View | ||||
| cerebral cavernous malformation 2 |
Ccm2tm1.1Etl/Ccm2tm1Etl Tg(Cdh5-cre/ERT2)1Rha/0 |
involves: 129 * C57BL/6 | J:177584 | View | ||||
| cerebral cavernous malformation 2 |
Ccm2tm1Kwhi/Ccm2tm1.1Kwhi Tg(Pdgfb-icre/ERT2,-EGFP)1Frut/? |
involves: C57BL/6 * CBA | J:173947 | View | ||||
| cerebral cavernous malformation 2 |
Ccm2tm1Mlkn/Ccm2tm1Mlkn Tg(Cdh5-cre/ERT2)1Rha/0 |
involves: 129 | J:250906 | View | ||||
| cerebral cavernous malformation 2 |
Ccm2tm2.1Sbn/Ccm2tm2.1Sbn Tg(Mx1-cre)1Cgn/0 |
involves: C57BL/6 * CBA | J:174085 | View | ||||
| cerebral cavernous malformation 3 |
Pdcd10tm1Kwhi/Pdcd10tm1.1Kwhi Tg(Pdgfb-icre/ERT2,-EGFP)1Frut/? |
involves: C57BL/6 * CBA | J:173947 | View | ||||
| cerebral cavernous malformation 3 |
Pdcd10tm1Wami/Pdcd10tm1Wami Tg(GFAP-cre)25Mes/0 |
involves: 129 * C57BL/6 * FVB/N | J:170480 | View | ||||
| | arteriovenous malformations of the brain | Acvrl1tm2.1Spo/Acvrl1tm2.1Spo | involves: 129 | J:196810 | View | |||
| arteriovenous malformations of the brain |
Tg(Tek-tTA)1Rwng/0 Tg(tetO-Notch4*)1Rwng/0 |
involves: FVB/N | J:139943 | View | ||||
| Transgenes and Other Mutations | brain ischemia | Tg(Notch3*R169C)88Bbb/0 | involves: FVB/N | J:156682 | View | |||
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No similarity to the expected human disease phenotype was found.
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
| NOT Models | cerebral cavernous malformation 2 |
Ccm2tm1Etl/Ccm2tm1Etl Tg(Nes-cre)1Kln/? |
B6.Cg-Ccm2tm1Etl Tg(Nes-cre)1Kln | J:146210 | View | |||
| cerebral cavernous malformation 2 |
Ccm2tm2.1Sbn/Ccm2tm2.1Sbn Tg(Tek-cre)1Ywa/0 |
involves: C57BL/6 * SJL | J:174085 | View | ||||
| Moyamoya disease | Rnf213tm1.1Mfuji/Rnf213tm1.1Mfuji | involves: C57BL/6 | J:229422 | View | ||||