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All mouse models of lymphatic system disease with phenotypic similarity to the human disease
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
  | B-cell lymphoma |
Ezh2tm1.1Nesh/Ezh2+ Cd19tm1(cre)Cgn/Cd19+ |
involves: 129 * 129P2/OlaHsd * C57BL/6 | J:239472 | View | |||
| Burkitt lymphoma | Ightm1(Myc)Janz/Igh+ | involves: 129X1/SvJ * C57BL/6 | J:96785 | View | ||||
| Burkitt lymphoma | Myctm1Lbox/Myc+ | involves: 129S1/Sv * 129X1/SvJ * FVB/N | J:97900 | View | ||||
| Burkitt lymphoma | Myctm1Lbox/Myctm1Lbox | involves: 129S1/Sv * 129X1/SvJ * FVB/N | J:97900 | View | ||||
| Burkitt lymphoma | Tg(IghMyc)22Bri/0 | involves: C57BL/6 * SJL | J:78177, J:186117 | View | ||||
| familial hemophagocytic lymphohistiocytosis 2 | Prf1tm1Sdz/Prf1tm1Sdz | C57BL/6-Prf1tm1Sdz/J | J:92260, J:193137 | View | ||||
| familial hemophagocytic lymphohistiocytosis 3 | Unc13dJinx/Unc13dJinx | C57BL/6J-Unc13dJinx/Mmucd | J:119974 | View | ||||
| familial hemophagocytic lymphohistiocytosis 4 | Stx11tm1.2Ics/Stx11tm1.2Ics | involves: C57BL/6NTac | J:193137 | View | ||||
| | central conducting lymphatic anomaly | Mdficem1Nlh/Mdficem2Nlh | C57BL/6J-Mdficem1Nlh/Mdficem2Nlh | J:326462 | View | |||
| diffuse large B-cell lymphoma | Smurf2Gt(RRA098)Byg/Smurf2Gt(RRA098)Byg | involves: 129P2/OlaHsd * C57BL/6 | J:245679 | View | ||||
| diffuse large B-cell lymphoma | Trp53tm1.2Awbr/Trp53tm1.2Awbr | involves: C57BL/6 | J:173271 | View | ||||
| diffuse large B-cell lymphoma |
Trp53tm1Tyj/Trp53tm1Tyj Tg(Ly6e-MALT1)#Isg/0 |
involves: 129S2/SvPas * C57BL/6 * CBA | J:185590 | View | ||||
| follicular lymphoma | Rarres1tm1.2Mhl/Rarres1+ | involves: 129S1/SvImJ * C57BL/6 * FVB/N * NIH Black Swiss | J:324270 | View | ||||
| follicular lymphoma | Rarres1tm1.2Mhl/Rarres1tm1.2Mhl | involves: 129S1/SvImJ * C57BL/6 * FVB/N * NIH Black Swiss | J:324270 | View | ||||
| follicular lymphoma | Rarres1tm1d(KOMP)Wtsi/Rarres1+ | involves: C57BL/6N | J:324270 | View | ||||
| hemophagocytic lymphohistiocytosis | Elp1Gt(BGB184)Byg/Elp1Gt(BGB184)Byg | B6.129P2-Gt(BGB184)Byg | J:145561 | View | ||||
| hemophagocytic lymphohistiocytosis | Rab27aash/Rab27aash | B6.C3Sn-Rab27aash | J:193137 | View | ||||
| hereditary lymphedema | Flt4Chy/Flt4+ | involves: C3H | J:72387 | View | ||||
| hereditary lymphedema | Vegfctm1Ali/Vegfc+ | involves: 129S1/Sv * 129X1/SvJ * ICR | J:209628 | View | ||||
| Langerhans-cell histiocytosis |
Braftm1Mmcm/Braftm1Mmcm Cd207tm2.1(cre)Bjec/Cd207+ |
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 | J:211690 | View | ||||
| Langerhans-cell histiocytosis |
Braftm1Mmcm/Braftm1Mmcm Tg(Itgax-cre)1-1Reiz/0 |
involves: 129P2/OlaHsd * C57BL/6 * CBA | J:211690 | View | ||||
| lymphatic system disease | Lgmntm1Ihn/Lgmntm1Ihn | involves: 129P2/OlaHsd * C57BL/6 | J:143886 | View | ||||
| lymphoma |
Gt(ROSA)26Sortm1(tTA,tetO-Mir155)Fjsl/Gt(ROSA)26Sor+ Tg(Nes-cre)1Wmz/0 |
involves: 129 * C57BL/6 * FVB/N * SJL/J | J:185598 | View | ||||
| lymphoma | Tg(H2-K-Hmga1)#Lmsr/0 | involves: C57BL/6 * SJL | J:90252 | View | ||||
| malignant histiocytic disease | Rcbtb2tm1.1Xyw/Rcbtb2+ | involves: C57BL/6 * CBA | J:282928 | View | ||||
| malignant histiocytic disease | Rcbtb2tm1.1Xyw/Rcbtb2tm1.1Xyw | involves: C57BL/6 * CBA | J:282928 | View | ||||
| non-Hodgkin lymphoma | Mtss1Gt(CSC156)Byg/Mtss1Gt(CSC156)Byg | B6.129P2-Mtss1Gt(CSC156)Byg | J:186118 | View | ||||
| non-Hodgkin lymphoma | S1pr2tm1Ajml/S1pr2tm1Ajml | 129S5/SvEvBrd-S1pr2tm1Ajml | J:154439 | View | ||||
| non-Hodgkin lymphoma | S1pr2tm1Ajml/S1pr2tm1Ajml | involves: 129S5/SvEvBrd * C57BL/6 | J:154439 | View | ||||
| peripheral T-cell lymphoma | Rc3h1san/Rc3h1+ | involves: C57BL/6JSfdAnu | J:189087 | View | ||||
| T-cell acute lymphoblastic leukemia |
Nbnem7Jpt/Nbntm2Zqw Tg(VAV1-cre)1Graf/0 |
involves: 129P2/OlaHsd | J:277750 | View | ||||
| T-cell acute lymphoblastic leukemia | Tg(H2-K-Hmga1)#Lmsr/0 | involves: C57BL/6 * SJL | J:90252 | View | ||||
| T-cell adult acute lymphocytic leukemia |
Gt(ROSA)26Sortm18(Zeb2)Jhai/Gt(ROSA)26Sortm18(Zeb2)Jhai Tg(Cd4-cre)1Cwi/0 |
involves: C57BL/6 * CD-1 * DBA/2 | J:263520 | View | ||||
| T-cell adult acute lymphocytic leukemia |
Gt(ROSA)26Sortm18(Zeb2)Jhai/Gt(ROSA)26Sortm18(Zeb2)Jhai Tg(Tek-cre)1Ywa/0 |
involves: C57BL/6 * CD-1 * SJL | J:263520 | View | ||||
| T-cell adult acute lymphocytic leukemia | Tg(Lck-Tax)53Hall/0 | involves: C57BL/6 | J:129531, J:214623 | View | ||||
| Transgenes and Other Mutations | Burkitt lymphoma | Tg(IGL-MYC)3Hm/0 | C57BL/6N-Tg(IGL-MYC)3Hm/Nci | J:65245 | View | |||
| chronic lymphocytic leukemia | Del(14Trim13-Dleu2)4Rdf/Del(14Trim13-Dleu2)4Rdf | involves: 129S1/Sv * 129S4/SvJaeSor * C57BL/6 | J:156946 | View | ||||
| chronic lymphocytic leukemia |
Del(14Trim13-Rnaseh2b)6Rdf/+ Cd19tm1(cre)Cgn/Cd19+ |
involves: 129P2/OlaHsd * 129S1/Sv * 129S4/SvJaeSor * C57BL/6 | J:179879 | View | ||||
| chronic lymphocytic leukemia |
Is(14)1Rdf Is(14)2Rdf/Del(14Trim13-Dleu2)4Rdf Cd19tm1(cre)Cgn/Cd19+ |
involves: 129P2/OlaHsd * 129S1/Sv * 129S4/SvJaeSor * C57BL/6 | J:156946 | View | ||||
| chronic lymphocytic leukemia |
Is(14)1Rdf Is(14)5Rdf/Del(14Trim13-Rnaseh2b)6Rdf Cd19tm1(cre)Cgn/Cd19+ |
involves: 129P2/OlaHsd * 129S1/Sv * 129S4/SvJaeSor * C57BL/6 | J:179879 | View | ||||
| chronic lymphocytic leukemia |
Mirc30em1Hhzg/Mirc30em1Hhzg Tg(Vav1-cre)#Cgp/0 |
involves: 129S4/SvJae * C57BL/6 * C57BL/6NRj | J:320883 | View | ||||
| chronic lymphocytic leukemia | Mirc30tm1.2Rdf/Mirc30tm1.2Rdf | involves: 129S1/Sv * 129S4/SvJaeSor * C57BL/6 | J:156946 | View | ||||
| chronic lymphocytic leukemia | Tg(Igh-Mir29a,-Mir29b-1,-hrGFP)#Cro/0 | FVB/N-Tg(Igh-Mir29a,-Mir29b-1,-hrGFP)#Cro | J:162077 | View | ||||
| chronic lymphocytic leukemia |
Tg(Igh-Mir29a,-Mir29b-1,-hrGFP)#Cro/0 Tg(Igh-V186.2-TCL1A)3Cro/0 |
involves: C3H * C57BL/6 * FVB/N | J:162077 | View | ||||
| chronic lymphocytic leukemia | Tg(Igh-ROR1)1Kip/0 | C57BL/6-Tg(Igh-ROR1)1Kip | J:206368 | View | ||||
| chronic lymphocytic leukemia |
Tg(Igh-ROR1)1Kip/0 Tg(Igh-V186.2-TCL1A)3Cro/0 |
B6.Cg-Tg(Igh-ROR1)1Kip Tg(Igh-V186.2-TCL1A)3Cro | J:206368 | View | ||||
| chronic lymphocytic leukemia | Tg(Igh-TCL1A)1Ypek/0 | FVB/N-Tg(Igh-TCL1A)1Ypek | J:160184 | View | ||||
| chronic lymphocytic leukemia | Tg(Igh-V186.2-TCL1A)3Cro/0 | B6.Cg-Tg(Igh-V186.2-TCL1A)3Cro | J:206368 | View | ||||
| chronic lymphocytic leukemia | Tg(Igh-V186.2-TCL1A)3Cro/0 | involves: C3H * C57BL/6 | J:76574 | View | ||||
| chronic lymphocytic leukemia | Tg(Lck-TNFSF13)3919Mhah/0 | B6.Cg-Tg(Lck-TNFSF13)3919Mhah | J:94628 | View | ||||
| extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue | Tg(Ly6e-MALT1)#Isg/0 | involves: C57BL/6 * CBA | J:185590 | View | ||||
| follicular lymphoma | Tg(Vav-BCL2)69Jad/0 | involves: C57BL/6J | J:88565 | View | ||||
| hereditary lymphedema | Del(8A4-B3)7H/+ | involves: 101/H * C3H/HeH | J:209628 | View | ||||
| lymphoma | Tg(Vav1-STAT5B*N642H)726Biat/0 | C57BL/6NCrl-Tg(Vav1-STAT5B*N642H)726Biat | J:257519 | View | ||||
| non-Hodgkin lymphoma | Tg(EmuSR-HDAC9)1468Kpet/0 | involves: C57BL/6 * CBA | J:237420 | View | ||||
| non-Hodgkin lymphoma |
Tg(EmuSR-tTa)83Bop/Tg(EmuSR-tTa)83Bop Tg(tetO-NPM1/ALK,-luc)2Gde/0 |
involves: FVB/N | J:160236 | View | ||||
| non-Hodgkin lymphoma |
Tg(EmuSR-tTa)83Bop/Tg(EmuSR-tTa)83Bop Tg(tetO-TPM3/ALK,-luc)2Gde/0 |
involves: FVB/N | J:160236 | View | ||||
| plasmacytoma | Tg(H2-L-IL6)46Kish/Tg(H2-L-IL6)46Kish | C.B6-Tg(H2-L-IL6)46Kish | J:74377 | View | ||||
| Additional Complex Models | B-cell lymphoma |
Cd19tm1(cre)Cgn/Cd19+ Inpp5dtm1Rav/Inpp5dtm1Rav Ptentm1Hwu/Ptentm1Hwu |
involves: 129P2/OlaHsd * 129S4/SvJae | J:166155 | View | |||
| chronic lymphocytic leukemia | Ightm1.1(Tag)Rwhe/Igh+ | involves: 129P2/OlaHsd * C57BL/6 | J:150315 | View | ||||
| chronic lymphocytic leukemia | Ightm2.1(Tag)Rwhe/Igh+ | involves: 129P2/OlaHsd * C57BL/6 | J:150315 | View | ||||
| chronic lymphocytic leukemia |
Ighatm1(Myc)Janz/Igha+ Tg(Tnfsf13b)1Fma/0 |
involves: 129S1/Sv * C57BL/6 * DBA/2J | J:166158 | View | ||||
| chronic lymphocytic leukemia |
Is(14)1Rdf/Is(14)1Rdf Is(14)5Rdf/Is(14)5Rdf Cd19tm1(cre)Cgn/Cd19+ |
involves: 129P2/OlaHsd * 129S1/Sv * 129S4/SvJaeSor * C57BL/6 | J:179879 | View | ||||
| chronic lymphocytic leukemia |
Tg(BCL2/IGH)#Jcre/0 Tg(H2-K/Igh-Traf2*)#Ywc/0 |
involves: BALB/c * C57BL/6 * CBA/J * FVB/N * SJL/J * SWR/J | J:94116 | View | ||||
| diffuse large B-cell lymphoma |
Cd19tm1(cre)Cgn/Cd19+ Gt(ROSA)26Sortm2(CARD11*L225LI)Jrld/Gt(ROSA)26Sor+ |
involves: 129P2/OlaHsd | J:228288 | View | ||||
| lymphoma | Epm2aTg(TcraK,TcrbK)TG-BFlv/Epm2a+ | involves: C57BL/6 * C57BL/10 * C57BR/cd * CBA/J | J:112696 | View | ||||
| lymphoma |
Espl1Gt(XL058)Byg/Espl1+ Trp53tm1Tyj/Trp53tm1Tyj |
B6.129-Trp53tm1Tyj Espl1Gt(XL058)Byg | J:174926 | View | ||||
| non-Hodgkin lymphoma |
Gt(ROSA)26Sortm4(Ikbkb)Rsky/Gt(ROSA)26Sor+ Ighg1tm1(cre)Cgn/Ighg1+ Prdm1tm2Masu/Prdm1tm2Masu |
involves: 129P2/OlaHsd * C57BL/6 | J:167612 | View | ||||
| non-Hodgkin lymphoma | Ighmtm1(Bcl6)Rdf/? | involves: 129/Sv * C57BL/6 | J:98937 | View | ||||