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All mouse models of chronic myeloid leukemia with phenotypic similarity to the human disease
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Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
chronic myeloid leukemia | Chordc1tm1Mbra/Chordc1+ | involves: 129 * C57BL/6 | J:222040 | View | ||||
chronic myeloid leukemia |
Ncstntm1.1Akli/Ncstntm1.1Akli Tg(Mx1-cre)1Cgn/0 |
involves: 129 * C57BL/6 * CBA * SJL | J:172442 | View | ||||
chronic myeloid leukemia |
Ncstntm1.1Akli/Ncstntm1.1Akli Tg(VAV1-cre)1Graf/0 |
involves: 129 * C57BL/6 * SJL | J:172442 | View | ||||
chronic myeloid leukemia | Sh2b3tm1Paw/Sh2b3tm1Paw | involves: 129S1/Sv * 129X1/SvJ | J:161643 | View | ||||
chronic myeloid leukemia | Sipa1tm1Nm/Sipa1+ | involves: 129P2/OlaHsd * C57BL/6 | J:97239 | View | ||||
chronic myeloid leukemia | Sipa1tm1Nm/Sipa1tm1Nm | involves: 129P2/OlaHsd * C57BL/6 | J:97239 | View | ||||
familial chronic myelocytic leukemia-like syndrome |
Irf8myls/Irf8myls Slc11a1r/Slc11a1r |
BXH2/TyJ | J:97931 | View | ||||
familial chronic myelocytic leukemia-like syndrome |
Irf8myls/Irf8myls Slc11a1r/Slc11a1r |
involves: A/J * BXH2/TyJ | J:97931 | View | ||||
familial chronic myelocytic leukemia-like syndrome | Irf8tm1Hor/Irf8+ | either: (involves: 129P2/OlaHsd) or (involves: 129P2/OlaHsd * C57BL/6) | J:36038 | View | ||||
familial chronic myelocytic leukemia-like syndrome | Irf8tm1Hor/Irf8tm1Hor | either: (involves: 129P2/OlaHsd) or (involves: 129P2/OlaHsd * C57BL/6) | J:36038 | View | ||||
Transgenes and Other Mutations | chronic myeloid leukemia |
Gt(ROSA)26Sortm4(CAG-hsb5)Nki/Gt(ROSA)26Sor+ Tg(Mx1-cre)1Cgn/0 Tg(Tal1-tTA)19Dgt/0 Tg(tetO-BCR/ABL1)2Dgt/0 TgTn(pb-sb-GrOnc)#aGsva/0 |
involves: 129P2/OlaHsd * C57BL/6 * CBA/J * DBA/2 * FVB/N | J:227558 | View | |||
chronic myeloid leukemia | Tg(Ly6a-BCR/ABL1)IS1AIsg/0 | involves: C57BL/6J * CBA | J:144382 | View | ||||
chronic myeloid leukemia | Tg(Ly6a-BCR/ABL1)IS1BIsg/0 | involves: C57BL/6J * CBA | J:144382 | View | ||||
chronic myeloid leukemia | Tg(Ly6a-TK,-BCR/ABL1)IS9AIsg/0 | involves: C57BL/6J * CBA | J:144382 | View | ||||
chronic myeloid leukemia |
Tg(tetO-BCR/ABL1)2Dgt/0 Tg(Tal1-tTA)19Dgt/0 |
involves: C57BL/6 * DBA/2 * FVB/N | J:96511 | View | ||||
Additional Complex Models | chronic myeloid leukemia |
Dok1tm1Ppp/Dok1+ Tg(Tec-BCR/ABL1)5Hhi/0 |
involves: 129S1/Sv | J:95334 | View | |||
chronic myeloid leukemia |
Dok1tm1Ppp/Dok1tm1Ppp Dok2tm1Ppp/Dok2tm1Ppp |
129S1/Sv-Dok1tm1Ppp Dok2tm1Ppp | J:95334 | View | ||||
chronic myeloid leukemia |
Dok1tm1Ppp/Dok1tm1Ppp Tg(Tec-BCR/ABL1)5Hhi/0 |
involves: 129S1/Sv | J:95334 | View | ||||
chronic myeloid leukemia |
Dok1tm1Yyam/Dok1tm1Yyam Dok2tm1Yyam/Dok2tm1Yyam |
B6.129-Dok1tm1Yyam Dok2tm1Yyam | J:95335 | View | ||||
chronic myeloid leukemia |
Dok1tm1Yyam/Dok1tm1Yyam Dok2tm1Yyam/Dok2tm1Yyam Tg(Tec-BCR/ABL1)5Hhi/0 |
involves: C57BL/6 | J:95335 | View | ||||
chronic myeloid leukemia |
Dok1tm1Yyam/Dok1tm1Yyam Tg(Tec-BCR/ABL1)5Hhi/0 |
involves: C57BL/6 | J:95335 | View | ||||
chronic myeloid leukemia |
Dok2tm1Ppp/Dok2+ Tg(Tec-BCR/ABL1)5Hhi/0 |
involves: 129S1/Sv | J:95334 | View | ||||
chronic myeloid leukemia |
Dok2tm1Ppp/Dok2tm1Ppp Tg(Tec-BCR/ABL1)5Hhi/0 |
involves: 129S1/Sv | J:95334 | View | ||||
chronic myeloid leukemia |
Dok2tm1Yyam/Dok2tm1Yyam Tg(Tec-BCR/ABL1)5Hhi/0 |
involves: C57BL/6 | J:95335 | View |