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All mouse models of systemic lupus erythematosus with phenotypic similarity to the human disease
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
  | systemic lupus erythematosus | C4btm1Crr/C4btm1Crr | involves: 129S4/SvJae * C57BL/6J | J:111811 | View | |||
| systemic lupus erythematosus |
Ccr2tm1Blck/Ccr2tm1Blck Faslpr/Faslpr |
MRL.Cg-Ccr2tm1Blck Faslpr | J:113343 | View | ||||
| systemic lupus erythematosus | Dnase1tm1Tmo/Dnase1tm1Tmo | involves: 129P2/OlaHsd * C57BL/6 | J:62549 | View | ||||
| systemic lupus erythematosus | Dnase1tm2092.1Arte/Dnase1tm2092.1Arte | involves: C57BL/6 | J:277126 | View | ||||
| systemic lupus erythematosus | Faslpr/Faslpr | MRL/Mp-Faslpr | J:27634, J:28885, J:108760, J:131138 | View | ||||
| systemic lupus erythematosus |
Faslpr/Faslpr Igh-Jtm2(3H9-VDJ*)Mwg/Igh-J+ |
MRL.Cg-Faslpr Igh-Jtm2(3H9-VDJ*)Mwg | J:131138 | View | ||||
| systemic lupus erythematosus |
Faslpr/Faslpr Tlr9tm1Aki/Tlr9tm1Aki |
MRL.Cg-Tlr9tm1Aki Faslpr | J:113557 | View | ||||
| systemic lupus erythematosus |
Faslpr/Faslpr Tnfrsf9tm1Byk/Tnfrsf9tm1Byk |
MRL.Cg-Tnfrsf9tm1Byk Faslpr | J:120559 | View | ||||
| systemic lupus erythematosus | Fcgr2btm1Ttk/Fcgr2btm1Ttk | B6.129S4-Fcgr2btm1Ttk | J:64152 | View | ||||
| systemic lupus erythematosus |
Fcgr2btm1Ttk/Fcgr2btm1Ttk Traf3ip2tm1Sbn/Traf3ip2+ |
involves: 129 * 129S4/SvJae * C57BL/6 | J:191090 | View | ||||
| systemic lupus erythematosus | Pdcd1tm1Hon/Pdcd1tm1Hon | B6.129S2-Pdcd1tm1Hon | J:78802 | View | ||||
| systemic lupus erythematosus | Pdcd1tm1Hon/Pdcd1tm1Hon | involves: 129S2/SvPas * C57BL/6 | J:50688 | View | ||||
| | systemic lupus erythematosus |
Atg5tm1Myok/Atg5tm1Myok Lyz2tm1(cre)Ifo/Lyz2+ |
involves: 129P2/OlaHsd * 129S/SvEv | J:235399 | View | |||
| systemic lupus erythematosus |
Atg7tm1Tchi/Atg7tm1Tchi Lyz2tm1(cre)Ifo/Lyz2+ |
involves: 129P2/OlaHsd * C57BL/6NCrlj * CBA/JNCrlj | J:235399 | View | ||||
| systemic lupus erythematosus |
Becn1tm1Ebr/Becn1tm1Ebr Lyz2tm1(cre)Ifo/Lyz2+ |
involves: 129P2/OlaHsd | J:235399 | View | ||||
| systemic lupus erythematosus | C1qatm1Mjw/C1qatm1Mjw | involves: 129P2/Ola * 129S/SvEv * C57BL/6 | J:47315 | View | ||||
| systemic lupus erythematosus |
Cd19tm1(cre)Cgn/Cd19+ Ep300tm2Reck/Ep300+ |
involves: 129/Sv * 129P2/OlaHsd * C57BL/6 | J:147840 | View | ||||
| systemic lupus erythematosus |
Cd79atm1(cre)Reth/Cd79a+ Inpp5dtm1Rav/Inpp5dtm1Rav |
involves: 129 * BALB/c * C57BL/6 | J:178833 | View | ||||
| systemic lupus erythematosus | Cdkn1atm1Led/Cdkn1atm1Led | involves: 129S6/SvEvTac | J:76041 | View | ||||
| systemic lupus erythematosus |
Cdkn1atm1Led/Cdkn1atm1Led Gadd45atm1Ajf/Gadd45atm1Ajf |
either: (involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6) or (involves: 129S6/SvEvTac * 129X1/SvJ * C57BL/6) | J:76041 | View | ||||
| systemic lupus erythematosus | Cybbtm1Din/Cybbtm1Din | B6.129S-Cybbtm1Din/J | J:235399 | View | ||||
| systemic lupus erythematosus | Def6Gt(OST307148)Lex/Def6Gt(OST307148)Lex | involves: 129S5/SvEvBrd * C57BL/6 | J:106469 | View | ||||
| systemic lupus erythematosus | Fam210bem1Cya/Fam210bem1Cya | involves: C57BL/6N | J:351618 | View | ||||
| systemic lupus erythematosus | Gadd45atm1Ajf/Gadd45atm1Ajf | either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129X1/SvJ * C57BL/6) | J:76041 | View | ||||
| systemic lupus erythematosus | Ifih1Rgsc422/Ifih1+ | D2JJcl.B6JJcl-Ifih1Rgsc422 | J:209917 | View | ||||
| systemic lupus erythematosus | Ifih1Rgsc422/Ifih1Rgsc422 | D2JJcl.B6JJcl-Ifih1Rgsc422 | J:209917 | View | ||||
| systemic lupus erythematosus | Ikzf3tm1Kge/Ikzf3tm1Kge | involves: 129S4/SvJae * C57BL/6 | J:50626, J:81805 | View | ||||
| systemic lupus erythematosus | Jak1M1Mhda/Jak1+ | C3HeB/FeJ-Jak1M1Mhda | J:199153 | View | ||||
| systemic lupus erythematosus |
Junbtm3Wag/Junbtm3Wag Tg(KRT5-cre)1Tak/0 |
involves: 129/Sv * 129P2/OlaHsd * C3H * C57BL/6 | J:155575 | View | ||||
| systemic lupus erythematosus |
KitW-sh/KitW-sh Lyntm1Ard/Lyntm1Ard |
involves: 101 * 129P2/OlaHsd * C3H/HeH | J:161523 | View | ||||
| systemic lupus erythematosus | Lbric-J/Lbr+ | (NZW/LacJ x C57BL/6J-Lbric-J/J)F1 | J:234168 | View | ||||
| systemic lupus erythematosus | Lyntm1Ard/Lyntm1Ard | involves: 129P2/OlaHsd | J:161523 | View | ||||
| systemic lupus erythematosus | Man2a1tm1Jxm/Man2a1tm1Jxm | involves: 129S1/Sv * 129X1/SvJ * C57BL/6 | J:74579 | View | ||||
| systemic lupus erythematosus | Mta2tm1.1Yzha/Mta2tm1.1Yzha | involves: 129S4/SvJae * C57BL/6 * FVB/N | J:137101 | View | ||||
| systemic lupus erythematosus | Pld4thss/Pld4thss | BALB/cJ-Pld4thss/GrsrJ | J:278304 | View | ||||
| systemic lupus erythematosus | Polbtm1.1Jbsw/Polbtm1.1Jbsw | involves: 129/Sv * C57BL/6 | J:206872 | View | ||||
| systemic lupus erythematosus |
Ppargtm1.1Gonz/Ppargtm1.1Gonz Lyz2tm1(cre)Ifo/Lyz2+ |
involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 | J:168799 | View | ||||
| systemic lupus erythematosus |
Prdm1tm1Clme/Prdm1tm1Clme Tg(Itgax-cre)1-1Reiz/0 |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA | J:178876 | View | ||||
| systemic lupus erythematosus |
Ptpn22tm2Achn/Ptpn22tm2Achn Ptprctm1Weis/Ptprctm1Weis |
B6.Cg-Ptprctm1Weis Ptpn22tm2Achn | J:147129 | View | ||||
| systemic lupus erythematosus | Ptprctm1Weis/Ptprc+ | involves: 129X1/SvJ * C57BL/6 | J:66501 | View | ||||
| systemic lupus erythematosus | Ptprctm1Weis/Ptprctm1Weis | involves: 129X1/SvJ * C57BL/6 | J:66501 | View | ||||
| systemic lupus erythematosus | Rasgrp1lag/Rasgrp1lag | involves: 129 * C57BL/6 | J:85189 | View | ||||
| systemic lupus erythematosus | Rassf5tm1Kina/Rassf5tm1Kina | B6.Cg-Rassf5tm1Kina | J:168749 | View | ||||
| systemic lupus erythematosus | Rc3h1san/Rc3h1san | either: C57BL/6JSfdAnu-Rc3h1san/Anu or (involves: C57BL/6JSfdAnu * CBA/Ca) | J:98938 | View | ||||
| systemic lupus erythematosus | Ro60tm1Woln/Ro60+ | involves: 129S1/Sv * C57BL/6 | J:84627 | View | ||||
| systemic lupus erythematosus | Ro60tm1Woln/Ro60tm1Woln | B6.129S1-Ro60tm1Woln | J:84627 | View | ||||
| systemic lupus erythematosus | Ro60tm1Woln/Ro60tm1Woln | involves: 129S1/Sv * C57BL/6 | J:84627 | View | ||||
| systemic lupus erythematosus | Rubcnem1Dgre/Rubcnem1Dgre | involves: C57BL/6 * C57BL/6N | J:235399 | View | ||||
| systemic lupus erythematosus |
Rxratm1Krc/Rxratm1Krc Lyz2tm1(cre)Ifo/Lyz2+ |
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 | J:168799 | View | ||||
| systemic lupus erythematosus | Tg(Igh-V-CD40lg)#Tsub/0 | C57BL/6-Tg(Igh-V-CD40lg)#Tsub | J:128824 | View | ||||
| systemic lupus erythematosus | Tg(Tlr7)1Boll/0 | involves: C57BL/6 | J:193610 | View | ||||
| systemic lupus erythematosus | Timd4tm1Kuch/Timd4tm1Kuch | involves: C57BL/6 | J:235399 | View | ||||
| systemic lupus erythematosus | Tlr7em2Anu/Tlr7+ | C57BL/6NCrl-Tlr7em2Anu | J:324448 | View | ||||
| systemic lupus erythematosus | Tlr7em2Anu/Tlr7em2Anu | C57BL/6NCrl-Tlr7em2Anu | J:324448 | View | ||||
| systemic lupus erythematosus | Tlr7em2Anu/Y | C57BL/6NCrl-Tlr7em2Anu | J:324448 | View | ||||
| systemic lupus erythematosus | Tnfrsf13btm1Vmd/Tnfrsf13btm1Vmd | involves: C57BL/6 | J:82331 | View | ||||
| systemic lupus erythematosus | Traf3ip2tm1.1Lix/Traf3ip2tm1.1Lix | B6.129-Traf3ip2tm1.1Lix | J:187766 | View | ||||
| Transgenes and Other Mutations | systemic lupus erythematosus |
Cd4tm1Mak/Cd4tm1Mak Igh-Jtm2(3H9-VDJ*)Mwg/Igh-J+ |
B6.Cg-Cd4tm1Mak Igh-Jtm2(3H9-VDJ*)Mwg | J:142389 | View | |||
| systemic lupus erythematosus | Igh-Jtm2(3H9-VDJ*)Mwg/Igh-J+ | B6.129P2-Igh-Jtm2(3H9-VDJ*)Mwg | J:142389 | View | ||||
| systemic lupus erythematosus |
Tcrbtm1Mom/Tcrbtm1Mom Tcrdtm1Mom/Tcrdtm1Mom Igh-Jtm2(3H9-VDJ*)Mwg/Igh-J+ |
B6.129P2-Tcrbtm1Mom Igh-Jtm2(3H9-VDJ*)Mwg Tcrdtm1Mom | J:142389 | View | ||||
| systemic lupus erythematosus | Tg(ACTB-TNFRSF6B)754Jwu/? | B6.Cg-Tg(Actb-TNFRSF6B)754Jwu | J:148162 | View | ||||
| systemic lupus erythematosus | X/Yaa | (NZB x BXSB)F1 | J:6235 | View | ||||
| systemic lupus erythematosus | X/Yaa | (NZW x BXSB)F1 | J:7276 | View | ||||
| systemic lupus erythematosus | X/Yaa | (NZW x SB)F1 | J:7276 | View | ||||
| systemic lupus erythematosus | X/Yaa | BXSB/MpJ | J:6235, J:108760, J:7308 | View | ||||
| systemic lupus erythematosus | X/Yaa | BXSB/MpJScr | J:10973 | View | ||||
| Additional Complex Models | systemic lupus erythematosus |
Apoetm1Unc/Apoetm1Unc Faslgld/Faslgld |
B6.Cg-Faslgld Apoetm1Unc | J:91058, J:200141 | View | |||
| systemic lupus erythematosus |
Csf2tm1Dran/Csf2tm1Dran Il3tm1Glli/Il3tm1Glli |
B6.129S2-Csf2tm1Dran Il3tm1Glli | J:83086 | View | ||||
| systemic lupus erythematosus |
Ightm1.1(Igh564)Tik/Ightm1.1(Igh564)Tik Igktm1(Igk564)Tik/Igktm1(Igk564)Tik |
B6.129S4-Igktm1(Igk564)Tik Ightm1(Igh564)Tik | J:113555 | View | ||||
| systemic lupus erythematosus |
Psen1tm1Bdes/Psen1+ Psen2tm1Bdes/Psen2tm1Bdes |
involves: 129P2/OlaHsd | J:91235 | View | ||||
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No similarity to the expected human disease phenotype was found.
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
| NOT Models | systemic lupus erythematosus |
Csf2tm1Dran/Csf2tm1Dran Ifngtm1Ts/Ifngtm1Ts Il3tm1Glli/Il3tm1Glli |
involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6 | J:83086 | View | |||
| systemic lupus erythematosus |
Tlr7tm1Flv/Y X/Yaa |
B6.Cg-Tlr7tm1Flv Yaa | J:127600 | View | ||||