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All mouse models of acute myeloid leukemia with phenotypic similarity to the human disease
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
  | acute myeloid leukemia | Cebpatm8.1Nerl/Cebpatm8.1Nerl | involves: 129P2/OlaHsd * BALB/cJ * C57BL/6 | J:136134 | View | |||
| acute myeloid leukemia | Crebbptm1Dli/Crebbp+ | involves: 129S6/SvEvTac * C57BL/6 | J:60630 | View | ||||
| acute myeloid leukemia | Flt3tm1.1Dosm/Flt3+ | B6.129(C)-Flt3tm1.1Dosm | J:205200 | View | ||||
| acute myeloid leukemia |
Flt3tm1Dgg/Flt3+ Kmt2atm1Clgr/Kmt2a+ |
involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6J | J:189096 | View | ||||
| acute myeloid leukemia |
Flt3tm1Dgg/Flt3tm1Dgg Kmt2atm1Clgr/Kmt2a+ |
involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6J | J:189096 | View | ||||
| acute myeloid leukemia | Flt3tm2.1Dosm/Flt3+ | B6.129(C)-Flt3tm2.1Dosm | J:205200 | View | ||||
| acute myeloid leukemia |
Kmt2atm1Saam/Kmt2a+ Tg(Mx1-cre)1Cgn/0 |
involves: 129S1/Sv * C57BL/6 * CBA | J:140628 | View | ||||
| acute myeloid leukemia | Kmt2atm2(MLLT3)Thr/Kmt2a+ | involves: 129P2/OlaHsd | J:56340 | View | ||||
| acute myeloid leukemia | Tg(Vav1-Asxl1*Y588X)#Fcy/0 | C57BL/6-Tg(Vav1-Asxl1*Y588X)#Fcy | J:257690 | View | ||||
| | acute myeloid leukemia | Arid4atm1Alb/Arid4atm1Alb | involves: 129S7/SvEvBrd | J:141004 | View | |||
| acute myeloid leukemia |
Arid4atm1Alb/Arid4atm1Alb Arid4btm1Alb/Arid4b+ |
involves: 129S7/SvEvBrd | J:141004 | View | ||||
| acute myeloid leukemia |
Mybl2tm1.1Jof/Mybl2+ Tg(Zp3-cre)3Mrt/0 |
involves: 129S2/SvPas * C57BL/6 * FVB/N | J:196804 | View | ||||
| acute myeloid leukemia | Spi1tm1.3Dgt/Spi1tm1.3Dgt | involves: 129 * BALB/c * C57BL/6 | J:90331 | View | ||||
| | acute promyelocytic leukemia |
Pmltm1.1Ews/Pmltm1.1Ews Tg(PML-RARA)556Kog/0 |
FVB.Cg-Pmltm1.1Ews Tg(PML-RARA)556Kog | J:262172 | View | |||
| acute promyelocytic leukemia |
Tg(CTSG-ZBTB16/RARA)#Ppp/0 Zbtb16tm1Ppp/Zbtb16tm1Ppp |
involves: 129S1/Sv | J:65878 | View | ||||
| Transgenes and Other Mutations | acute myeloid leukemia | Tg(CMV-SALL4_iB)#Chai/? | Not Specified | J:115037 | View | |||
| acute myeloid leukemia | Tg(Vav1-ERG)#Jpim/0 | involves: C57BL/6 | J:203438 | View | ||||
| acute promyelocytic leukemia | Tg(CTSG-NUMA1/RARA)#Skr/0 | involves: C57BL/6 | J:88103 | View | ||||
| acute promyelocytic leukemia | Tg(PML-RARA)556Kog/? | involves: FVB/N | J:39327 | View | ||||
| Additional Complex Models | acute myeloid leukemia | Ctsgtm2.1(PML/RARA)Ley/Ctsg+ | involves: 129X1/SvJ * C57BL/6 | J:84230, J:86458 | View | |||
| acute myeloid leukemia |
Nr4a1tm1Jmi/Nr4a1tm1Jmi Nr4a3tm1Omc/Nr4a3tm1Omc |
involves: 129S/SvEv * 129S2/SvPas * C57BL/6 | J:121903 | View | ||||
| acute promyelocytic leukemia |
Tg(CTSG-RARA/ZBTB16)#Ppp/0 Tg(CTSG-ZBTB16/RARA)#Ppp/0 |
Not Specified | J:65878 | View | ||||
| acute promyelocytic leukemia |
Tg(CTSG-RARA/ZBTB16)#Sjch/0 Tg(CTSG-ZBTB16/RARA)#Sjch/0 |
Not Specified | J:194312 | View | ||||
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No similarity to the expected human disease phenotype was found.
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
| NOT Models | acute myeloid leukemia |
Krastm4Tyj/Kras+ Tg(Mx1-cre)1Cgn/0 |
involves: 129S4/SvJae * C57BL/6 * CBA | J:87429 | View | |||
| acute myeloid leukemia | Npm1tm1Hft/Npm1+ | involves: 129 | J:194999 | View | ||||