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All mouse models of type 2 diabetes mellitus with phenotypic similarity to the human disease
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
  | type 2 diabetes mellitus | Akt2tm1.1Mbb/Akt2tm1.1Mbb | involves: 129P2/OlaHsd * C57BL/6 | J:71491 | View | |||
| type 2 diabetes mellitus |
Cdkal1tm1.1Tomik/Cdkal1tm1.1Tomik Tg(Ins2-cre)25Mgn/0 |
B6.Cg-Cdkal1tm1.1Tomik Tg(Ins2-cre)25Mgn | J:178248 | View | ||||
| type 2 diabetes mellitus | Cyb5r4tm1Hfb/Cyb5r4tm1Hfb | involves: 129S4/SvJae * BALB/cAnN | J:91486 | View | ||||
| type 2 diabetes mellitus |
Gcktm1Tka/Gck+ Irs1tm1Tka/Irs1tm1Tka |
involves: 129X1/SvJ * C57BL/6 * CBA * ICR | J:38899 | View | ||||
| type 2 diabetes mellitus | Gcktm1Tka/Gcktm1Tka | involves: 129X1/SvJ * ICR | J:30334 | View | ||||
| type 2 diabetes mellitus | Hmga1tm1Brun/Hmga1+ | Not Specified | J:99652 | View | ||||
| type 2 diabetes mellitus | Hmga1tm1Brun/Hmga1tm1Brun | Not Specified | J:99652 | View | ||||
| type 2 diabetes mellitus | Hnf1atm1.1Ylee/Hnf1atm1.1Ylee | involves: 129X1/SvJ * C57BL/6J | J:47008 | View | ||||
| type 2 diabetes mellitus | Ins2Akita/? | involves: C57BL/6NSlc | J:130021 | View | ||||
| type 2 diabetes mellitus |
Irs1tm1Jos/Irs1+ Irs2tm2Mfw/Irs2tm2Mfw Tg(Ins2-cre)25Mgn/0 |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 | J:93415 | View | ||||
| type 2 diabetes mellitus | Irs1tm1Tka/Irs1tm1Tka | Not Specified | J:21373 | View | ||||
| type 2 diabetes mellitus | Irs2tm1Mfw/Irs2tm1Mfw | involves: 129S1/Sv * 129X1/SvJ * C57BL/6J | J:46134 | View | ||||
| type 2 diabetes mellitus | Irs2tm1Tka/Irs2tm1Tka | involves: C57BL/6 * CBA | J:65485 | View | ||||
| type 2 diabetes mellitus |
Irs2tm2Mfw/Irs2tm2Mfw Tg(Ins2-cre)25Mgn/0 |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 | J:93415 | View | ||||
| type 2 diabetes mellitus | Lepob/Lepob | BTBR.Cg-Lepob/WiscJ | J:106121 | View | ||||
| type 2 diabetes mellitus | Leprbrta/Leprbrta | C57BL/6JSfdAnu-Leprbrta/Anu | J:104190 | View | ||||
| type 2 diabetes mellitus |
Leprdb/Lepr+ Tg(APPswe,PSEN1dE9)85Dbo/0 |
involves: C3H * C57BL/6 * C57BLKS/J | J:186924 | View | ||||
| type 2 diabetes mellitus | Leprdb/Leprdb | BKS.Cg-Dock7m +/+ Leprdb | J:346348 | View | ||||
| type 2 diabetes mellitus | Leprdb/Leprdb | BKS.Cg-Dock7m +/+ Leprdb/J | J:185546 | View | ||||
| type 2 diabetes mellitus | Leprdb/Leprdb | involves: C57BLKS/J | J:104790 | View | ||||
| type 2 diabetes mellitus |
Leprdb/Leprdb Nos3tm1Unc/Nos3tm1Unc |
BKS.Cg-Leprdb Nos3tm1Unc | J:135864 | View | ||||
| type 2 diabetes mellitus | LeprTg(Mth11)1Aig/LeprTg(Mth11)1Aig | involves: Him:OF1 | J:61119 | View | ||||
| type 2 diabetes mellitus | Leprtm1Jke/Leprtm1Jke | involves: 129X1/SvJ | J:216393 | View | ||||
| type 2 diabetes mellitus | Ppardtm1Dsvg/Ppardtm1Dsvg | involves: 129S2/SvPas * C57BL/6 | J:219677 | View | ||||
| type 2 diabetes mellitus | Ppp1r3atm1Ptwc/Ppp1r3atm1Ptwc | involves: 129P2/OlaHsd * C57BL/6J | J:82422 | View | ||||
| type 2 diabetes mellitus | Slc2a2tm1Thor/Slc2a2tm1Thor | involves: 129P2/OlaHsd * C57BL/6J | J:43839 | View | ||||
| type 2 diabetes mellitus | Slc2a4tm1Mch/Slc2a4+ | involves: 129/Sv * C57BL/6J * CD-1 * SJL | J:43650 | View | ||||
| type 2 diabetes mellitus | Tg(Ins2-IAPP)L13Gjsc/0 | FVB/N-Tg(Ins2-IAPP)L13Gjsc | J:142009 | View | ||||
| | type 2 diabetes mellitus | Ay/a | involves: KK | J:26460 | View | |||
| type 2 diabetes mellitus |
Artm1Verh/Y Tg(Fabp4-cre)1Rev/0 |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 | J:196857 | View | ||||
| type 2 diabetes mellitus | Ctf1tm1Msd/Ctf1tm1Msd | B6.Cg-Ctf1tm1Msd | J:176727 | View | ||||
| type 2 diabetes mellitus | Fem1btm1Jfma/Fem1btm1Jfma | involves: 129X1/SvJ * C57BL/6 | J:100017 | View | ||||
| type 2 diabetes mellitus |
Foxm1tm1Rhc/Foxm1tm1Rhc Tg(Pdx1-cre)89.1Dam/0 |
involves: 129X1/SvJ * C57BL/6 * CBA | J:111026 | View | ||||
| type 2 diabetes mellitus |
Gadd45gip1tm2Kong/Gadd45gip1tm2Kong Tg(Ins2-cre)25Mgn/0 |
involves: 129P2/OlaHsd * C57BL/6 * DBA | J:220742 | View | ||||
| type 2 diabetes mellitus | Htr2ctm1Jul/Y | B6.129S-Htr2ctm1Jul | J:50262 | View | ||||
| type 2 diabetes mellitus |
Maddtm1Bpra/Maddtm1Bpra Tg(Ins2-cre/ERT)1Dam/0 |
involves: 129P2/OlaHsd * C57BL/6 * CBA | J:225256 | View | ||||
| type 2 diabetes mellitus | Mafatm1Staka/Mafatm1Staka | involves: ICR | J:99126 | View | ||||
| type 2 diabetes mellitus | Phox2a/Inppl1tm1Ssch/Phox2a/Inppl1tm1Ssch | involves: 129S1/Sv * 129X1/SvJ * C57BL/6 | J:96443 | View | ||||
| type 2 diabetes mellitus | Phox2a/Inppl1tm1Ssch/Phox2a+ | involves: 129S1/Sv * 129X1/SvJ * C57BL/6 | J:96443 | View | ||||
| type 2 diabetes mellitus | Ppp1r3ctm1Ars/Ppp1r3c+ | B6.129-Ppp1r3ctm1Ars | J:83297 | View | ||||
| type 2 diabetes mellitus |
Prkcitm1Rfar/Prkci+ Tg(Ckmm-cre)5Khn/? |
involves: 129P2/OlaHsd * C57BL/6 * FVB | J:123964 | View | ||||
| type 2 diabetes mellitus |
Sdhbtm1c(EUCOMM)Hmgu/Sdhbtm1c(EUCOMM)Hmgu Tg(Ins2-cre)23Herr/0 |
involves: C57BL/6J * C57BL/6N * CBA/J | J:326592 | View | ||||
| type 2 diabetes mellitus | Snap25tm1.1Bark/Snap25tm1.1Bark | Not Specified | J:226064 | View | ||||
| type 2 diabetes mellitus | Tg(Mafg-Nfe2l1)1Mym/0 | involves: C57BL/6J * DBA/2 | J:230118 | View | ||||
| type 2 diabetes mellitus | Tg(Mafg-Nfe2l1)6Mym/0 | involves: C57BL/6J * DBA/2 | J:230118 | View | ||||
| | type 2 diabetes mellitus |
Insrtm1Dac/Insr+ Ppp2r2aigt10/Ppp2r2a+ |
involves: 129S4/SvJae * C3H/HeH * C57BL/6J | J:246319 | View | |||
| type 2 diabetes mellitus |
Pdx1tm1Cvw/Pdx1+ Pbx1tm1Mlc/Pbx1+ |
involves: 129S6/SvEvTac * C57BL/6 | J:75811 | View | ||||
| Transgenes and Other Mutations | type 2 diabetes mellitus | Tg(aP2-SREBF1c)9884Reh/0 | involves: C57BL/6J * SJL | J:50770 | View | |||
| type 2 diabetes mellitus |
Tg(APOB)11Rub/0 Tg(UcpDta)1Kz/0 |
involves: C57BL/6J * FVB/N | J:78211 | View | ||||
| type 2 diabetes mellitus | Tg(Ckm-IGF1R*K1003R)1Dlr/0 | FVB/N-Tg(Ckm-IGF1R*K1003R)1Dlr | J:71205, J:210518 | View | ||||
| type 2 diabetes mellitus | Tg(UcpDta)1Kz/? | involves: FVB/N | J:78211 | View | ||||
| type 2 diabetes mellitus | Timo/Timo | either: B6.Cg-Timo or (involves: C57BL/6J * CBA/CaJ) | J:127183 | View | ||||