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All mouse models of leukocyte disease with phenotypic similarity to the human disease
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Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
hereditary neutrophilia | Csf3rtm1Eur/Csf3rtm1Eur | involves: 129P2/OlaHsd * C57BL/6 * FVB | J:48503 | View | ||||
leukocyte adhesion deficiency 1 | Itgb2tm1Bay/Itgb2tm1Bay | involves: 129S7/SvEvBrd | J:13599 | View | ||||
leukocyte adhesion deficiency 1 | Itgb2tm1Bay/Itgb2tm1Bay | involves: 129S7/SvEvBrd * C57BL/6J | J:13599 | View | ||||
leukocyte adhesion deficiency 1 | Itgb2tm2Bay/Itgb2tm2Bay | involves: 129S7/SvEvBrd * C57BL/6J | J:48542 | View | ||||
leukocyte adhesion deficiency 3 | Fermt3tm1Ref/Fermt3tm1Ref | involves: 129S1/Sv * 129X1/SvJ | J:146783 | View | ||||
mastocytosis |
Tg(Cma1-cre)ARoer/0 Tg(Kit*D814V)1Roer/0 |
involves: C57BL/6 | J:169611 | View | ||||
mastocytosis |
Tg(Cma1-cre)ARoer/0 Tg(Kit*D814V)3Roer/0 |
involves: C57BL/6 | J:169611 | View | ||||
mastocytosis |
Tg(Kit*D814V)1Roer/0 Tg(Mx1-cre)1Cgn/0 |
involves: C57BL/6 * CBA | J:169611 | View | ||||
mastocytosis |
Tg(Kit*D814V)2Roer/0 Tg(Mx1-cre)1Cgn/0 |
involves: C57BL/6 * CBA | J:169611 | View | ||||
mastocytosis |
Tg(Kit*D814V)3Roer/0 Tg(Mx1-cre)1Cgn/0 |
involves: C57BL/6 * CBA | J:169611 | View | ||||
leukocyte adhesion deficiency 3 | Rasgrp2tm1Amg/Rasgrp2tm1Amg | Not Specified | J:122618 | View | ||||
leukopenia | Nudt15em1Maska/Nudt15+ | C57BL/6-Nudt15em1Maska | J:285800 | View | ||||
leukopenia | Nudt15em1Maska/Nudt15em1Maska | C57BL/6-Nudt15em1Maska | J:285800 | View | ||||
multiple myeloma | Tg(Igh-Maf)68Staka/0 | C57BL/6-Tg(Igh-Maf)68Staka | J:168074 | View | ||||
multiple myeloma | Tg(Igh-Maf)524Staka/0 | involves: C57BL/6 * C57BL/6J * DBA/2 | J:168074 | View | ||||
neutropenia | Nudt15em1Maska/Nudt15+ | C57BL/6-Nudt15em1Maska | J:285800 | View | ||||
neutropenia | Nudt15em1Maska/Nudt15em1Maska | C57BL/6-Nudt15em1Maska | J:285800 | View | ||||
severe congenital neutropenia | Gfi1Gen/Gfi1+ | C57BL/6J-Gfi1Gen | J:182679 | View | ||||
Transgenes and Other Mutations | multiple myeloma | Tg(Cd4-NPM/ALK)N1Ingh/0 | either: (involves: BALB/c * Swiss Webster) or (involves: C57BL/6 * Swiss Webster) | J:82127 | View | |||
multiple myeloma | Tg(Igkv3-5*-MYC)24Plbe/0 | C57BL/6J-Tg(Igkv3-5*-MYC)DLoxP4Plbe/PlbeMmmh | J:131912 | View | ||||
Additional Complex Models | multiple myeloma |
Ightm1(Myc)Janz/Igh+ Tg(Emu-FGFR3)A5Wmk/0 |
involves: 129X1/SvJ * C57BL/6 * FVB/N | J:160845 | View | |||
multiple myeloma |
Ightm1(Myc)Janz/Igh+ Tg(Emu-FGFR3)D3Wmk/0 |
involves: 129X1/SvJ * C57BL/6 * FVB/N | J:160845 | View |