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All mouse models of adrenal gland disease with phenotypic similarity to the human disease
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
  | corticosteroid-binding globulin deficiency | Serpina6tm1.1Mmp/Serpina6tm1.1Mmp | involves: 129S2/SvPas * C57BL/6 * C57BL/6J * SJL | J:164345, J:192931 | View | |||
| corticosteroid-binding globulin deficiency | Serpina6tm1Tew/Serpina6tm1Tew | involves: 129/SvEmcTer * C57BL/6N | J:112974 | View | ||||
| primary hyperaldosteronism | Clcn2em1Uis/Clcn2+ | C57BL/6N-Clcn2em1Uis | J:282228 | View | ||||
| X-linked adrenal hypoplasia congenita | Nr0b1tm1.1Lja/Y | involves: 129S1/Sv * 129X1/SvJ | J:51292, J:71710 | View | ||||
| | adrenal gland disease | Mraptm1.2Geno/Mraptm1.2Geno | involves: C57BL/6 | J:278935 | View | |||
| primary hyperaldosteronism | Drd2tm1Ebo/Drd2tm1Ebo | involves: 129S2/SvPas * C57BL/6 | J:110599 | View | ||||
| primary hyperaldosteronism |
Nr3c1tm2Gsc/Nr3c1tm2Gsc Tg(Nes-cre)1Kln/0 |
involves: 129P2/OlaHsd * C57BL/6J * SJL | J:57315 | View | ||||
| primary pigmented nodular adrenocortical disease |
Prkar1atm1Lsk/Prkar1atm1Lsk Tg(Akr1b7-cre)1Anm/0 |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2 | J:161521 | View | ||||
| Transgenes and Other Mutations | primary hyperaldosteronism | Rr609m1H/Rr609+ | involves: C3H/HeH * C57BL/6J | J:208708 | View | |||
| primary hyperaldosteronism | Tg(Crh)227.1Pbl/0 | involves: C57BL/6 * SJL | J:92996 | View | ||||
| primary pigmented nodular adrenocortical disease |
Tg(CMV-tTA)3Bjd/0 Tg(tetO-Prkar1a*x2as)1Stra/0 |
involves: C57BL/6 * NMRI * SJL | J:95465 | View | ||||
| Additional Complex Models | primary hyperaldosteronism |
Kcnk3tm1.1Daba/Kcnk3tm1.1Daba Kcnk9tm1.1Daba/Kcnk9tm1.1Daba |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA | J:131927 | View | |||