Excel File Text File All mouse models of pulmonary emphysema with phenotypic similarity to the human disease
        Disease Term Allelic Composition Genetic Background Reference Phenotypes
      pulmonary emphysema Bloc1s6pa/Bloc1s6pa B6.Cg-Bloc1s6pa/J J:4098 View
pulmonary emphysema Fstl1tm1Ajn/Fstl1tm1Ajn B6.Cg-Fstl1tm1Ajn J:322116 View
pulmonary emphysema Fut8tm1Nta/Fut8tm1Nta involves: 129S2/SvPas J:102932 View
pulmonary emphysema Gli2tm1(cre/ERT2)Tipe/Gli2+
Gt(ROSA)26Sortm1(Smo/EYFP)Amc/Gt(ROSA)26Sor+
involves: 129X1/SvJ J:264185 View
pulmonary emphysema Itgb6tm1Des/Itgb6tm1Des involves: 129T2/SvEms J:89578 View
pulmonary emphysema Juntm4Wag/Juntm4Wag
Tg(Sftpc-cre)1Blh/0
involves: 129P2/OlaHsd * C57BL/6 * DBA/2 J:179883 View
pulmonary emphysema Klkl/Klkl either: C.Cg-Klkl or (involves: C3H/HeJ * C57BL/6J) J:44109 View
pulmonary emphysema Mus81tm1Esse/Mus81tm1Esse involves: 129P2/OlaHsd * C57BL/6J J:222498 View
pulmonary emphysema Tg(Actb-Ptma)T12Clwu/0 involves: FVB/N J:270215 View
pulmonary emphysema Tg(Actb-Ptma)T12Clwu/Tg(Actb-Ptma)T12Clwu involves: FVB/N J:270215 View
pulmonary emphysema Tlr4tm1Aki/Tlr4tm1Aki B6.129P2-Tlr4tm1Aki J:114985 View
      pulmonary emphysema Fbn1Tsk/Fbn1+
Tgfb1tm1N/Tgfb1+
involves: 129S/SvEv * C57BL/6J * C57BL/10 * DBA/2 J:68448 View
pulmonary emphysema Serpina1em1Chmu/Serpina1em1Chmu involves: C57BL/6J J:259615 View
pulmonary emphysema Serpina1em2Chmu/Serpina1em2Chmu involves: C57BL/6J J:259615 View
pulmonary emphysema Serpina1em3Chmu/Serpina1em3Chmu involves: C57BL/6J J:259615 View
pulmonary emphysema Serpina1em#Chmu/Serpina1em#Chmu involves: C57BL/6J J:259615 View
Transgenes and
Other Mutations
     pulmonary emphysema Tg(HP-MMP1a)34-1Cha/0 involves: C57BL/6J * CBA/J J:164058 View
pulmonary emphysema Tg(HP-MMP1a)34-1Cha/Tg(HP-MMP1a)34-1Cha involves: C57BL/6J * CBA/J J:164058 View
pulmonary emphysema Tg(Msr1-MMP9)#Apar/0 B6.Cg-Tg(Msr1-MMP9)#Apar J:136830 View
pulmonary emphysema Tg(SFTPC-rtTA)5Jaw/0
Tg(tetO-PLAGL2)P3Ysy/0
involves: FVB/N J:152422 View
Additional
Complex
Models
     pulmonary emphysema Fbn1Tsk/Fbn1+ B6.Cg-Fbn1Tsk J:30961, J:6566, J:15018, J:1326, J:68448 View
pulmonary emphysema Fbn1Tsk/Fbn1+
Il4ratm1Sz/Il4ra+
involves: BALB/cJ * C57BL/6J * C57BL/10 * DBA/2 J:68448 View
pulmonary emphysema Fbn1Tsk/Fbn1+
Il4ratm1Sz/Il4ratm1Sz
involves: BALB/cJ * C57BL/6J * C57BL/10 * DBA/2 J:68448 View


       
No similarity to the expected human disease phenotype was found.
        Disease Term Allelic Composition Genetic Background Reference Phenotypes
NOT Models      pulmonary emphysema Itgb6tm1Des/Itgb6tm1Des
Mmp12tm1Sds/Mmp12tm1Sds
involves: 129/Sv * 129T2/SvEms J:89578 View