Symbol Name ID |
Pten
phosphatase and tensin homolog MGI:109583 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Subcutaneous lipoma |
Lipoma |
Multiple lipomas |
Disease(s) Associated with PTEN | |||
Bannayan-Riley-Ruvalcaba syndrome | |||
macrocephaly-autism syndrome |
Mouse Phenotypes | adipose tissue phenotype |
abnormal adipose tissue morphology |
decreased total body fat amount |
decreased body fat mass |
abnormal brown adipose tissue morphology |
decreased brown fat cell lipid droplet size |
decreased white fat cell size |
decreased epididymal fat pad weight |
increased adipocyte glucose uptake |
abnormal brown adipose tissue physiology |
|
Availability | Mouse Genotype | ||||||||||
Tg(Pten)1Srn/0 | |||||||||||
Ptentm1Hwu/Ptentm1Hwu Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ (conditional) |
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Ptentm1Hwu/Ptentm1Hwu Tg(Fabp4-cre)1Abel/0 (conditional) |
* |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/21/2024 MGI 6.24 |
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