Symbol Name ID |
Fmr1
fragile X messenger ribonucleoprotein 1 MGI:95564 |
* | Aspects of the system are reported to show a normal phenotype. |
! | Indicates phenotype varies with strain background. |
Darker colors indicate more annotations |
Human Phenotypes | Bowel incontinence |
Urinary incontinence |
Depression |
Autism |
Obsessive-compulsive trait |
Disinhibition |
Hyperactivity |
Attention deficit hyperactivity disorder |
Recurrent hand flapping |
Self-injurious behavior |
Self-biting |
Myalgia |
Disease(s) Associated with FMR1 | ||||||||||||
fragile X syndrome | ||||||||||||
fragile X-associated tremor/ataxia syndrome |
Mouse Phenotypes | behavior/neurological phenotype |
abnormal behavior |
abnormal learning/memory/conditioning |
abnormal associative learning |
impaired passive avoidance behavior |
impaired conditioned place preference behavior |
impaired cued conditioning behavior |
abnormal eye blink conditioning behavior |
abnormal object recognition memory |
increased exploration in new environment |
abnormal spatial learning |
hypodipsia |
decreased aggression towards mice |
increased aggression towards mice |
abnormal anxiety-related response |
decreased anxiety-related response |
increased anxiety-related response |
abnormal response to novelty |
abnormal response to novel object |
abnormal response to social novelty |
increased grooming behavior |
abnormal startle reflex |
decreased startle reflex |
increased startle reflex |
impaired coordination |
decreased grip strength |
abnormal locomotor activation |
increased vertical activity |
decreased locomotor activity |
increased locomotor activity |
hyperactivity |
increased stereotypic behavior |
abnormal circadian behavior |
increased thermal nociceptive threshold |
abnormal social investigation |
decreased social investigation |
social withdrawal |
abnormal vocalization |
decreased vocalization |
audiogenic seizures |
convulsive seizures |
tonic-clonic seizures |
|
Availability | Mouse Genotype | ||||||||||||||||||||||||||||||||||||||||||
Fmr1tm1.1Ics/Fmr1tm1.1Ics | |||||||||||||||||||||||||||||||||||||||||||
Fmr1tm1Cgr/Fmr1tm1Cgr | *! | ||||||||||||||||||||||||||||||||||||||||||
Fmr1tm1Cgr/Y | *! | ! | ! | ! | ! | ! | ! | ! | ! | ! | ! | ! | ! | ! | |||||||||||||||||||||||||||||
Fmr1tm1Rbd/Y | |||||||||||||||||||||||||||||||||||||||||||
Fmr1tm1Usdn/Y | |||||||||||||||||||||||||||||||||||||||||||
Fmr1tm2Cgr/Y | |||||||||||||||||||||||||||||||||||||||||||
Fmr1tm1.1Cidz/Fmr1tm1.1Cidz Tg(Pcp2-cre)2Mpin/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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