Symbol Name ID |
Htt
huntingtin MGI:96067 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Depression |
Personality changes |
Disease(s) Associated with HTT | ||
Huntington's disease |
Mouse Phenotypes | behavior/neurological phenotype |
abnormal behavior |
abnormal learning/memory/conditioning |
abnormal motor learning |
increased aggression towards mice |
increased thigmotaxis |
increased grooming behavior |
abnormal motor capabilities/coordination/movement |
limb grasping |
tremors |
abnormal motor coordination/balance |
enhanced coordination |
impaired balance |
impaired coordination |
impaired limb coordination |
decreased grip strength |
increased grip strength |
hunched posture |
straub tail |
abnormal locomotor activation |
abnormal locomotor coordination |
abnormal gait |
long stride length |
short stride length |
decreased vertical activity |
increased vertical activity |
decreased locomotor activity |
increased locomotor activity |
hyperactivity |
bradykinesia |
paralysis |
hyperresponsive |
seizures |
environmentally induced seizures |
tonic-clonic seizures |
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Availability | Mouse Genotype | |||||||||||||||||||||||||||||||||||
Htttm1Detl/Htttm1Detl | * | |||||||||||||||||||||||||||||||||||
Htttm1Mfc/Htttm1Mfc | ||||||||||||||||||||||||||||||||||||
Htttm2Detl/Htttm2Detl | ||||||||||||||||||||||||||||||||||||
Htttm4Mem/Htttm4Mem | ||||||||||||||||||||||||||||||||||||
Htttm5Mem/Htttm5Mem | * | |||||||||||||||||||||||||||||||||||
Htttm6Mem/Htttm6Mem | ||||||||||||||||||||||||||||||||||||
Httem1(IMPC)H/Htt+ | ||||||||||||||||||||||||||||||||||||
Htttm1.1Pfs/Htt+ | ||||||||||||||||||||||||||||||||||||
Htttm1Detl/Htt+ | * | |||||||||||||||||||||||||||||||||||
Htttm1Hay/Htt+ | ||||||||||||||||||||||||||||||||||||
Htttm1Mem/Htttm6Mem | ||||||||||||||||||||||||||||||||||||
Htttm2.1Pfs/Htt+ | ||||||||||||||||||||||||||||||||||||
Htttm2Detl/Htt+ | ||||||||||||||||||||||||||||||||||||
Htttm5Detl/Htt+ | * | |||||||||||||||||||||||||||||||||||
Htttm6Mem/Htttm8Mem | ||||||||||||||||||||||||||||||||||||
Htttm1Mem/Htttm6Mem Tg(CAG-cre/Esr1*)5Amc/0 (conditional) |
* | |||||||||||||||||||||||||||||||||||
Htttm1Szi/Htttm2Szi Tg(Camk2a-cre)1Szi/0 (conditional) |
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Htttm1Szi/Htttm2Szi Tg(Camk2a-cre)2Szi/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 07/05/2024 MGI 6.24 |
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