Symbol
Name
ID

Ighmbp2
immunoglobulin mu DNA binding protein 2
MGI:99954

Phenotype annotations related to behavior/neurological

Darker colors indicate more annotations

Human Phenotypes	Decreased fetal movement	Urinary incontinence	Weak cry
Disease(s) Associated with IGHMBP2
autosomal recessive distal hereditary motor neuronopathy 1

Mouse Phenotypes

abnormal food intake

dysphagia

impaired righting response

limb grasping

abnormal motor coordination/balance

impaired coordination

abnormal grip strength

decreased grip strength

abnormal gait

hindlimb paralysis

paraparesis

allodynia

increased thermal nociceptive threshold

Availability

Mouse Genotype

Ighmbp2^em1Cll/Ighmbp2^em1Cll

Ighmbp2^em1Cx/Ighmbp2^em1Cx

Ighmbp2^em5Cx/Ighmbp2^em5Cx

Ighmbp2^nmd-2J/Ighmbp2^nmd-2J

Ighmbp2^nmd-2J/Ighmbp2^nmd-2J
Tg(Ttn-Ighmbp2)45Cx/?

Ighmbp2^nmd-2J/Ighmbp2^nmd-2J
Tg(Ttn-Ighmbp2)108Cx/?

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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