Symbol Name ID |
Myh11
myosin, heavy polypeptide 11, smooth muscle MGI:102643 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Subarachnoid hemorrhage |
Bruising susceptibility |
Abnormal cardiovascular system morphology |
Bicuspid aortic valve |
Cardiomegaly |
Neoplasm of the heart |
Ascending aortic dissection |
Aortic aneurysm |
Abdominal aortic aneurysm |
Thoracic aortic aneurysm |
Aortic root aneurysm |
Ascending tubular aorta aneurysm |
Descending thoracic aorta aneurysm |
Aortic dissection |
Descending aortic dissection |
Aortic rupture |
Mucoid extracellular matrix accumulation |
Patent ductus arteriosus |
Carotid artery dilatation |
Carotid artery stenosis |
Anterior cerebral artery stenosis |
Middle cerebral artery stenosis |
Posterior cerebral artery stenosis |
Dilatation of the cerebral artery |
Moyamoya phenomenon |
Coronary artery aneurysm |
Coronary artery atherosclerosis |
Premature coronary artery atherosclerosis |
Coronary artery dissection |
Peripheral arterial stenosis |
Cystic medial necrosis |
Stroke |
Ischemic stroke |
Transient ischemic attack |
Abnormal left ventricular function |
Aortic regurgitation |
Hypertension |
Hypovolemia |
Cutis marmorata |
Livedo reticularis |
Disease(s) Associated with MYH11 | ||||||||||||||||||||||||||||||||||||||||
megacystis-microcolon-intestinal hypoperistalsis syndrome | ||||||||||||||||||||||||||||||||||||||||
patent ductus arteriosus | ||||||||||||||||||||||||||||||||||||||||
thoracic aortic aneurysm |
Mouse Phenotypes | cardiovascular system phenotype |
abnormal vascular regression |
dilated heart left ventricle |
thin ventricular wall |
dilated cardiomyopathy |
decreased mean systemic arterial blood pressure |
abnormal vascular smooth muscle physiology |
increased vascular smooth muscle cell proliferation |
decreased vasoconstriction |
abnormal vascular wound healing |
|
Availability | Mouse Genotype | ||||||||||
Myh11tm1.1Dmmz/Myh11tm1.1Dmmz | * | ||||||||||
Myh11tm1Bdr/Myh11tm1Bdr |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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