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Symbol Name ID |
Ppara
peroxisome proliferator activated receptor alpha MGI:104740 |
| Darker colors indicate more annotations |
| Human Phenotypes | Premature coronary artery atherosclerosis |
Hypertension |
Sudden cardiac death |
Myocardial infarction |
| Disease(s) Associated with PPARA | ||||
| coronary artery disease |
| Mouse Phenotypes | abnormal vascular endothelial cell morphology |
abnormal myocardium layer morphology |
abnormal myocardial fiber morphology |
myocardial fiber degeneration |
myocardium necrosis |
cardiac hypertrophy |
cardiac fibrosis |
abnormal cardiovascular system physiology |
decreased cardiac muscle cell glucose uptake |
decreased heart ventricle muscle contractility |
abnormal myocardial fiber physiology |
decreased systemic arterial systolic blood pressure |
hypotension |
cardiomyopathy |
heart inflammation |
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| Availability | Mouse Genotype | |||||||||||||||
| Pparatm1Gonz/Pparatm1Gonz | ||||||||||||||||
| Tg(Myh6-Ppara)402-2Dpk/0 | ||||||||||||||||
| Tg(Myh6-Ppara)404-3Dpk/0 | ||||||||||||||||
| Tg(Myh6-Ppara)404-4Dpk/0 | ||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 06/12/2024 MGI 6.13 |
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