Symbol Name ID |
Hccs
holocytochrome c synthetase MGI:106911 |
Darker colors indicate more annotations |
Human Phenotypes | Atrial septal defect |
Ventricular septal defect |
Histiocytoid cardiomyopathy |
Overriding aorta |
Arrhythmia |
Junctional ectopic tachycardia |
Disease(s) Associated with HCCS | ||||||
linear skin defects with multiple congenital anomalies 1 |
Mouse Phenotypes | decreased cardiac muscle glycogen level |
abnormal myocardium layer morphology |
abnormal fetal cardiomyocyte morphology |
abnormal fetal cardiomyocyte mitochondrial morphology |
decreased fetal cardiomyocyte size |
dilated heart atrium |
enlarged heart |
dilated heart left ventricle |
thick ventricular wall |
dilated heart right ventricle |
cardiac interstitial fibrosis |
dilated cardiomyopathy |
abnormal fetal cardiomyocyte proliferation |
decreased fetal cardiomyocyte proliferation |
atrioventricular block |
sinoatrial block |
bundle branch block |
abnormal myocardial fiber physiology |
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Availability | Mouse Genotype | ||||||||||||||||||
Hccstm1Tcc/Hccs+ Nkx2-5tm2(cre)Rph/Nkx2-5+ (conditional) |
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Hccstm1Tcc/Hccs+ Nkx2-5tm2(cre)Rph/Nkx2-5+ Tg(CAG-EGFP)D4Nagy/0 Tg(Hmgcr-lacZ)H253Sest/0 (conditional) |
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Hccstm1Tcc/Y Nkx2-5tm2(cre)Rph/Nkx2-5+ (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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