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Symbol
Name
ID
Ptgis
prostaglandin I2 (prostacyclin) synthase
MGI:1097156
Phenotype annotations related to cardiovascular system
Darker colors indicate more annotations
Human Phenotypes
Right ventricular dilatation
Abnormal cardiovascular system physiology
Heart murmur
Tricuspid regurgitation
Pulmonary arterial hypertension
Elevated jugular venous pressure
Palpitations
Syncope
Disease(s) Associated with PTGIS
primary pulmonary hypertension

Mouse Phenotypes
abnormal aorta wall morphology
abnormal aorta tunica adventitia morphology
abnormal aorta tunica media morphology
abnormal thoracic aorta morphology
kidney vascular congestion
abnormal heart morphology
increased heart weight
enlarged heart
increased systemic arterial blood pressure
Availability Mouse Genotype
Ptgisem1(IMPC)Mbp/Ptgisem1(IMPC)Mbp
Ptgistm1Tada/Ptgistm1Tada

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
07/02/2024
MGI 6.13
The Jackson Laboratory