Symbol Name ID |
Lrp5
low density lipoprotein receptor-related protein 5 MGI:1278315 |
Darker colors indicate more annotations |
Human Phenotypes | Vitreous hemorrhage |
Abnormal cardiovascular system morphology |
Ventricular septal defect |
Mitral valve prolapse |
Aortic root aneurysm |
Abnormal systemic arterial morphology |
Dilatation of the cerebral artery |
Hypertension |
Peripheral retinal avascularization |
Peripheral retinal neovascularization |
Posterior retinal neovascularization |
Disease(s) Associated with LRP5 | |||||||||||
autosomal dominant polycystic kidney disease | |||||||||||
exudative vitreoretinopathy 4 | |||||||||||
neovascular inflammatory vitreoretinopathy | |||||||||||
osteoporosis-pseudoglioma syndrome |
Mouse Phenotypes | abnormal retina vasculature morphology |
abnormal retina blood vessel morphology |
decreased angiogenesis |
abnormal vascular plexus formation |
blood vessel congestion |
hemorrhage |
increased vascular permeability |
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Availability | Mouse Genotype | |||||||
Lrp5em1Xjz/Lrp5em1Xjz | ||||||||
Lrp5Gt(OST164883)Lex/Lrp5Gt(OST164883)Lex | ||||||||
Lrp5r18/Lrp5r18 | ||||||||
Lrp5tm1Dgen/Lrp5tm1Dgen | ||||||||
Lrp5tm1Kry/Lrp5tm1Kry | ||||||||
Lrp5tvrm111B/Lrp5tvrm111B |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 09/03/2024 MGI 6.24 |
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