Symbol
Name
ID

Acta2
actin alpha 2, smooth muscle, aorta
MGI:87909

Phenotype annotations related to cardiovascular system

Darker colors indicate more annotations

Human Phenotypes

Cerebral hemorrhage

Subarachnoid hemorrhage

Bruising susceptibility

Bicuspid aortic valve

Dilated cardiomyopathy

Cardiomegaly

Ascending aortic dissection

Abdominal aortic aneurysm

Aortic root aneurysm

Descending thoracic aorta aneurysm

Aortic dissection

Descending aortic dissection

Mucoid extracellular matrix accumulation

Patent ductus arteriosus

Carotid artery dilatation

Dilatation of the cerebral artery

Moyamoya phenomenon

Coronary artery atherosclerosis

Peripheral arterial stenosis

Abnormal cerebral vascular morphology

Stroke

Ischemic stroke

Transient ischemic attack

Abnormal left ventricular function

Aortic regurgitation

Hypertension

Raynaud phenomenon

Hypovolemia

Cutis marmorata

Telangiectasia

Disease(s) Associated with ACTA2

Moyamoya disease

thoracic aortic aneurysm

Mouse Phenotypes		abnormal aorta morphology	abnormal aorta elastic tissue morphology	decreased heart weight	abnormal blood flow velocity	abnormal systemic arterial blood pressure	decreased systemic arterial systolic blood pressure	increased vascular permeability	decreased vasoconstriction
Availability	Mouse Genotype	abnormal aorta morphology	abnormal aorta elastic tissue morphology	decreased heart weight	abnormal blood flow velocity	abnormal systemic arterial blood pressure	decreased systemic arterial systolic blood pressure	increased vascular permeability	decreased vasoconstriction
	Acta2^em1(IMPC)H/Acta2^em1(IMPC)H
	Acta2^tm1Rjs/Acta2^tm1Rjs

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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