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Symbol
Name
ID

F2
coagulation factor II
MGI:88380

Phenotype annotations related to cardiovascular system

Darker colors indicate more annotations

Human Phenotypes

Gastrointestinal hemorrhage

Hematemesis

Melena

Intracranial hemorrhage

Intraventricular hemorrhage

Joint hemorrhage

Muscle hemorrhage

Bruising susceptibility

Purpura

Ecchymosis

Petechiae

Spontaneous hematomas

Pericarditis

Premature coronary artery atherosclerosis

Stroke

Elevated diastolic blood pressure

Elevated systolic blood pressure

Hypertension

Raynaud phenomenon

Sudden cardiac death

Myocardial infarction

Abnormality of the hepatic vasculature

Lymphadenopathy

Splenic rupture

Hepatosplenomegaly

Disease(s) Associated with F2

cerebral infarction

coronary artery disease

factor VIII deficiency

hemophilia B

pre-eclampsia

prothrombin deficiency

systemic lupus erythematosus

Mouse Phenotypes		abnormal vitelline vasculature morphology	hemopericardium	distended pericardium	hemorrhage	internal hemorrhage	intestinal hemorrhage	intracranial hemorrhage	subcutaneous hemorrhage
Availability	Mouse Genotype	abnormal vitelline vasculature morphology	hemopericardium	distended pericardium	hemorrhage	internal hemorrhage	intestinal hemorrhage	intracranial hemorrhage	subcutaneous hemorrhage
	F2^tm1Jes/F2^tm1Jes
	F2^tm1Sjd/F2^tm1Sjd
	F2^tm2Jld/F2^tm2Jld

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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