Symbol Name ID |
Cyp11b1
cytochrome P450, family 11, subfamily b, polypeptide 1 MGI:88583 |
Darker colors indicate more annotations |
Human Phenotypes | Dilated cardiomyopathy |
Hypotension |
Orthostatic hypotension |
Elevated diastolic blood pressure |
Elevated systolic blood pressure |
Hypertension |
Hypovolemia |
Abnormality of the hepatic vasculature |
Hepatosplenomegaly |
Disease(s) Associated with CYP11B1 | |||||||||
congenital adrenal hyperplasia | |||||||||
glucocorticoid-remediable aldosteronism | |||||||||
primary hyperaldosteronism | |||||||||
Disease(s) Associated with CYP11B2 | |||||||||
corticosterone methyloxidase deficiency 1 | |||||||||
dilated cardiomyopathy 1H | |||||||||
pre-eclampsia | |||||||||
primary hyperaldosteronism |
Mouse Phenotypes | increased myocardial fiber size |
increased heart weight |
cardiac fibrosis |
hypotension |
increased systemic arterial blood pressure |
increased systemic arterial systolic blood pressure |
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Availability | Mouse Genotype | ||||||
Cyp11b1tm1Chjk/Cyp11b1tm1Chjk | |||||||
Cyp11b2tm1Hsk/Cyp11b2tm1Hsk | |||||||
Cyp11b2tm2Hsk/Cyp11b2tm2Hsk |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 07/05/2024 MGI 6.24 |
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