Symbol Name ID |
Eng
endoglin MGI:95392 |
* | Aspects of the system are reported to show a normal phenotype. |
! | Indicates phenotype varies with strain background. |
Darker colors indicate more annotations |
Human Phenotypes | Gastrointestinal hemorrhage |
Hematemesis |
Hematochezia |
Melena |
Cerebral hemorrhage |
Subarachnoid hemorrhage |
Pulmonary hemorrhage |
Spontaneous hematomas |
Lip telangiectasia |
Oral cavity telangiectasia |
Palate telangiectasia |
Tongue telangiectasia |
Nasal mucosa telangiectasia |
Conjunctival telangiectasia |
Palmar telangiectasia |
Dilatation of celiac artery |
Dilatation of mesenteric artery |
Arteriovenous fistulas of celiac and mesenteric vessels |
Venous varicosities of celiac and mesenteric vessels |
Arteriovenous malformation |
Peripheral arteriovenous fistula |
Cerebral arteriovenous malformation |
Gastrointestinal arteriovenous malformation |
Hepatic arteriovenous malformation |
Pulmonary arteriovenous malformation |
Spinal arteriovenous malformation |
Abnormal cerebral vascular morphology |
Ischemic stroke |
Transient ischemic attack |
Gastrointestinal angiodysplasia |
Gastrointestinal telangiectasia |
Abnormal cardiovascular system physiology |
Hypertension |
Portal hypertension |
Pulmonary arterial hypertension |
Pulmonary embolism |
Right-to-left shunt |
Congestive heart failure |
High-output congestive heart failure |
Retinal telangiectasia |
Cavernous hemangioma |
Visceral angiomatosis |
Telangiectasia |
Mucosal telangiectasiae |
Nail bed telangiectasia |
Telangiectasia of the skin |
Facial telangiectasia |
Fingerpad telangiectases |
Disease(s) Associated with ENG | ||||||||||||||||||||||||||||||||||||||||||||||||
arteriovenous malformations of the brain | ||||||||||||||||||||||||||||||||||||||||||||||||
hereditary hemorrhagic telangiectasia |
Mouse Phenotypes | cardiovascular system phenotype |
abnormal blood vessel morphology |
abnormal dorsal aorta morphology |
abnormal carotid artery morphology |
abnormal capillary morphology |
cerebral arteriovenous malformation |
abnormal intersomitic vessel morphology |
abnormal vascular development |
decreased angiogenesis |
abnormal perineural vascular plexus morphology |
abnormal vitelline vasculature morphology |
absent vitelline blood vessels |
abnormal vascular smooth muscle morphology |
arteriovenous malformation |
gastrointestinal arteriovenous malformation |
blood vessel atresia |
thin myocardium |
abnormal cardiac outflow tract development |
abnormal heart development |
abnormal heart looping |
failure of heart looping |
abnormal heart morphology |
abnormal endocardium morphology |
enlarged heart |
increased heart ventricle size |
pericardial edema |
pericardial effusion |
hemorrhage |
internal hemorrhage |
hemoperitoneum |
absent heartbeat |
ear telangiectasia |
neck telangiectasia |
tail telangiectasia |
abnormal vascular wound healing |
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Availability | Mouse Genotype | |||||||||||||||||||||||||||||||||||
Engem1(IMPC)Mbp/Engem1(IMPC)Mbp | ||||||||||||||||||||||||||||||||||||
Engtm1Dyl/Engtm1Dyl | ||||||||||||||||||||||||||||||||||||
Engtm1Hma/Engtm1Hma | ||||||||||||||||||||||||||||||||||||
Engtm1Mle/Engtm1Mle | ||||||||||||||||||||||||||||||||||||
Engtm2.2Hma/Engtm2.2Hma | ||||||||||||||||||||||||||||||||||||
Engtm1Hma/Eng+ | ||||||||||||||||||||||||||||||||||||
Engtm1Mle/Eng+ | *! | |||||||||||||||||||||||||||||||||||
Engtm2.1Hma/Engtm2.1Hma (conditional) | ||||||||||||||||||||||||||||||||||||
Engtm2.1Hma/Engtm2.1Hma Gt(ROSA)26Sortm1(cre/ERT)Nat/Gt(ROSA)26Sor+ (conditional) |
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Engtm2.1Hma/Engtm2.1Hma Tg(Tal1-cre/ERT)1Jrg/0 (conditional) |
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Engtm2.1Hma/Engtm2.1Hma Tg(Myh11-icre/ERT2)1Soff/0 (conditional) |
* | |||||||||||||||||||||||||||||||||||
Engtm2.1Hma/Engtm2.1Hma Lyz2tm1(cre)Ifo/Lyz2+ (conditional) |
* | |||||||||||||||||||||||||||||||||||
Engtm2.1Hma/Engtm2.1Hma Tg(Tagln-cre)1Her/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 07/05/2024 MGI 6.24 |
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