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Symbol
Name
ID

Lox
lysyl oxidase
MGI:96817

Phenotype annotations related to cardiovascular system

Darker colors indicate more annotations

Human Phenotypes

Subarachnoid hemorrhage

Bruising susceptibility

Bicuspid aortic valve

Cardiomegaly

Ascending aortic dissection

Abdominal aortic aneurysm

Aortic root aneurysm

Descending thoracic aorta aneurysm

Aortic dissection

Descending aortic dissection

Mucoid extracellular matrix accumulation

Patent ductus arteriosus

Carotid artery dilatation

Dilatation of the cerebral artery

Coronary artery atherosclerosis

Peripheral arterial stenosis

Stroke

Ischemic stroke

Transient ischemic attack

Abnormal left ventricular function

Aortic regurgitation

Hypertension

Hypovolemia

Cutis marmorata

Disease(s) Associated with LOX

thoracic aortic aneurysm

Mouse Phenotypes

abnormal blood vessel morphology

abnormal pulmonary artery morphology

pulmonary artery stenosis

abnormal aorta wall morphology

abnormal aorta elastic tissue morphology

decreased aorta elastin content

abnormal aorta smooth muscle morphology

decreased aorta wall thickness

abnormal descending thoracic aorta morphology

supravalvar aortic stenosis

aorta stenosis

aortic aneurysm

abnormal blood vessel elastic tissue morphology

heart left ventricle hypertrophy

heart right ventricle hypertrophy

abnormal blood flow velocity

hemothorax

hemorrhage

hemoperitoneum

semilunar valve regurgitation

Availability

Mouse Genotype

Lox^b2b370.2Clo/Lox^b2b370.2Clo

Lox^tm1Ikh/Lox^tm1Ikh

Lox^tm1Soin/Lox^tm1Soin

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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