Symbol Name ID |
Mmp2
matrix metallopeptidase 2 MGI:97009 |
Darker colors indicate more annotations |
Human Phenotypes | Gastrointestinal hemorrhage |
Retinal hemorrhage |
Cerebral hemorrhage |
Bruising susceptibility |
Retinal arteritis |
Abnormal cardiovascular system morphology |
Double outlet right ventricle with subpulmonary ventricular septal defect without pulmonary stenosis |
Abnormal endocardium morphology |
Mitral valve prolapse |
Restrictive cardiomyopathy |
Pericarditis |
Abdominal aortic aneurysm |
Aortic dissection |
Coronary artery atherosclerosis |
Medial calcification of large arteries |
Medial calcification of medium-sized arteries |
Arterial stenosis |
Premature occlusive vascular stenosis |
Arteriosclerosis |
Atherosclerosis |
Accelerated atherosclerosis |
Vascular dilatation |
Vasculitis |
Abnormal cerebral vascular morphology |
Stroke |
Mitral stenosis |
Hypertension |
Renovascular hypertension |
Weak pulse |
Intermittent claudication |
Cerebral ischemia |
Arrhythmia |
Sudden cardiac death |
Angina pectoris |
Congestive heart failure |
Mediastinal lymphadenopathy |
Telangiectasia of the skin |
Disease(s) Associated with MMP2 | |||||||||||||||||||||||||||||||||||||
pseudoxanthoma elasticum | |||||||||||||||||||||||||||||||||||||
temporal arteritis |
Mouse Phenotypes | abnormal induced retina neovascularization |
abnormal angiogenesis |
decreased angiogenesis |
abnormal heart morphology |
enlarged heart |
dilated heart left ventricle |
abnormal cardiovascular system physiology |
abnormal response to cardiac infarction |
abnormal vascular smooth muscle physiology |
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Availability | Mouse Genotype | |||||||||
Mmp2em1(IMPC)Mbp/Mmp2em1(IMPC)Mbp | ||||||||||
Mmp2tm1Ito/Mmp2tm1Ito |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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