Symbol Name ID |
Myh6
myosin, heavy polypeptide 6, cardiac muscle, alpha MGI:97255 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Unroofed coronary sinus |
Atrial septal defect |
Primum atrial septal defect |
Secundum atrial septal defect |
Sinus venosus atrial septal defect |
Right ventricular dilatation |
Cardiomegaly |
Stroke |
Systolic heart murmur |
Pulmonary arterial hypertension |
Right axis deviation |
Palpitations |
Atrial fibrillation |
Atrial flutter |
Right bundle branch block |
Congestive heart failure |
Disease(s) Associated with MYH6 | ||||||||||||||||
atrial heart septal defect |
Mouse Phenotypes | cardiovascular system phenotype |
abnormal myocardium layer morphology |
abnormal myocardial fiber morphology |
increased myocardial fiber size |
myocardial fiber disarray |
calcified myocardium |
disorganized myocardium |
myocardium hypertrophy |
myocardium necrosis |
heart left ventricle hypertrophy |
abnormal heart morphology |
abnormal heart atrium morphology |
increased heart atrium size |
dilated heart atrium |
increased heart weight |
cardiac hypertrophy |
abnormal heart ventricle morphology |
abnormal heart left ventricle morphology |
decreased heart left ventricle wall thickness |
dilated heart left ventricle |
thick ventricular wall |
cardiac fibrosis |
cardiac interstitial fibrosis |
dilated cardiomyopathy |
dystrophic cardiac calcinosis |
abnormal cardiovascular system physiology |
decreased cardiac output |
decreased cardiac stroke volume |
decreased cardiac muscle contractility |
decreased heart ventricle muscle contractility |
increased cardiac muscle contractility |
increased heart left ventricle muscle contractility |
abnormal cardiac muscle relaxation |
abnormal heart echocardiography feature |
abnormal heart ventricle pressure |
decreased left ventricle diastolic pressure |
decreased left ventricle systolic pressure |
irregular heartbeat |
abnormal myocardial fiber physiology |
increased cardiomyocyte apoptosis |
cardiomyopathy |
|
Availability | Mouse Genotype | |||||||||||||||||||||||||||||||||||||||||
Myh6tm1.1Jpsc/Myh6tm1.1Jpsc | * | |||||||||||||||||||||||||||||||||||||||||
Myh6tm1Ces/Myh6tm1Ces | ||||||||||||||||||||||||||||||||||||||||||
Myh6tm1Jse/Myh6tm1Jse | ||||||||||||||||||||||||||||||||||||||||||
Myh6tm2Ces/Myh6tm2Ces | ||||||||||||||||||||||||||||||||||||||||||
Myh6tm2Jse/Myh6tm2Jse | ||||||||||||||||||||||||||||||||||||||||||
Myh6tm3.1Jse/Myh6tm3.1Jse | ||||||||||||||||||||||||||||||||||||||||||
Myh6tm1.1Jpsc/Myh6+ | * | |||||||||||||||||||||||||||||||||||||||||
Myh6tm1.1Jpsc/Myh6tm2Jse | ||||||||||||||||||||||||||||||||||||||||||
Myh6tm1Ces/Myh6+ | ||||||||||||||||||||||||||||||||||||||||||
Myh6tm1Jse/Myh6+ | ||||||||||||||||||||||||||||||||||||||||||
Myh6tm1Rbns/Myh6+ | ||||||||||||||||||||||||||||||||||||||||||
Myh6tm2Ces/Myh6+ | ||||||||||||||||||||||||||||||||||||||||||
Myh6tm2Jse/Myh6+ | ||||||||||||||||||||||||||||||||||||||||||
Myh6tm3.1Jse/Myh6+ |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 07/02/2024 MGI 6.13 |
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