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Symbol
Name
ID
Nppa
natriuretic peptide type A
MGI:97367
Phenotype annotations related to cardiovascular system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Palpitations
Atrial fibrillation
Myocardial infarction
Syncope
Disease(s) Associated with NPPA
familial atrial fibrillation

Mouse Phenotypes
cardiovascular system phenotype
abnormal vascular smooth muscle morphology
heart left ventricle hypertrophy
heart right ventricle hypertrophy
increased heart weight
enlarged heart
abnormal cardiovascular system physiology
decreased cardiac output
abnormal vascular resistance
abnormal heart right ventricle pressure
increased right ventricle peak pressure
increased heart rate
pulmonary hypertension
abnormal systemic arterial blood pressure
hypertension
salt-sensitive hypertension
increased systemic arterial diastolic blood pressure
Availability Mouse Genotype
Nppatm1Unc/Nppatm1Unc *
Nppatm1Unc/Nppa+

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
07/02/2024
MGI 6.13
The Jackson Laboratory