Symbol Name ID |
Pdgfb
platelet derived growth factor, B polypeptide MGI:97528 |
Darker colors indicate more annotations |
Human Phenotypes | Calcification of the small brain vessels |
Disease(s) Associated with PDGFB | |
basal ganglia calcification |
Mouse Phenotypes | abnormal blood vessel morphology |
abnormal artery morphology |
abnormal aorta smooth muscle morphology |
dilated aorta |
abnormal vascular endothelial cell morphology |
increased vascular endothelial cell number |
abnormal capillary morphology |
decreased capillary density |
dilated glomerular capillary |
increased capillary tortuosity |
brain aneurysm |
abnormal retina vasculature morphology |
kidney microaneurysm |
abnormal pericyte morphology |
abnormal placenta vasculature |
abnormal placental labyrinth vasculature morphology |
abnormal vascular smooth muscle morphology |
thin myocardium |
abnormal coronary vessel morphology |
enlarged heart |
dilated heart left ventricle |
abnormal heart right ventricle morphology |
dilated heart right ventricle |
hemorrhage |
intracerebral hemorrhage |
impaired blood-brain barrier function |
congestive heart failure |
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Availability | Mouse Genotype | |||||||||||||||||||||||||||
Pdgfbtm1Cbet/Pdgfbtm1Cbet | ||||||||||||||||||||||||||||
Pdgfbtm3.1Cbet/Pdgfbtm3.1Cbet | ||||||||||||||||||||||||||||
Pdgfbtm3.1Cbet/Pdgfbtm3.1Cbet Tg(Fabp4-lacZ)4Mosh/0 |
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Pdgfbtm1Cbet/Pdgfbtm3.1Cbet | ||||||||||||||||||||||||||||
Pdgfbtm1Cbet/Pdgfbtm2Cbet Tg(Tie1-cre)9Ref/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/21/2024 MGI 6.24 |
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