Symbol Name ID |
Pdgfrb
platelet derived growth factor receptor, beta polypeptide MGI:97531 |
! | Indicates phenotype varies with strain background. |
Darker colors indicate more annotations |
Human Phenotypes | Calcification of the small brain vessels |
Disease(s) Associated with PDGFRB | |
basal ganglia calcification |
Mouse Phenotypes | abnormal blood vessel morphology |
abnormal pulmonary artery morphology |
increased aorta wall thickness |
right aortic arch |
vascular ring |
abnormal left subclavian artery morphology |
abnormal vascular endothelial cell morphology |
increased vascular endothelial cell number |
decreased glomerular capillary number |
abnormal retina vasculature morphology |
abnormal retina blood vessel morphology |
abnormal retina blood vessel pattern |
abnormal kidney vasculature morphology |
abnormal pericyte morphology |
abnormal placenta vasculature |
abnormal placental labyrinth vasculature morphology |
abnormal angiogenesis |
decreased angiogenesis |
abnormal venule morphology |
abnormal heart morphology |
double outlet right ventricle |
overriding aortic valve |
dilated heart atrium |
atrioventricular septal defect |
perimembraneous ventricular septal defect |
muscular ventricular septal defect |
ventricular septal defect |
enlarged heart |
increased heart ventricle size |
cardiac fibrosis |
hemorrhage |
eye hemorrhage |
intracranial hemorrhage |
kidney hemorrhage |
glomerulus hemorrhage |
skin hemorrhage |
increased vascular permeability |
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Availability | Mouse Genotype | |||||||||||||||||||||||||||||||||||||
Pdgfrbb2b2903Clo/Pdgfrbb2b2903Clo | ||||||||||||||||||||||||||||||||||||||
Pdgfrbredeye/Pdgfrbredeye | ! | |||||||||||||||||||||||||||||||||||||
Pdgfrbtm1Sor/Pdgfrbtm1Sor | ||||||||||||||||||||||||||||||||||||||
Pdgfrbtm2Sor/Pdgfrbtm2Sor | ||||||||||||||||||||||||||||||||||||||
Pdgfrbtm7Sor/Pdgfrbtm7Sor | ||||||||||||||||||||||||||||||||||||||
Pdgfrbtm8Sor/Pdgfrbtm8Sor | ||||||||||||||||||||||||||||||||||||||
Pdgfrbtm9Sor/Pdgfrbtm9Sor | ||||||||||||||||||||||||||||||||||||||
Pdgfrbtm10Sor/Pdgfrbtm10Sor | ||||||||||||||||||||||||||||||||||||||
Pdgfrbtm1b(EUCOMM)Hmgu/Pdgfrb+ | ||||||||||||||||||||||||||||||||||||||
Pdgfrbtm1Sor/Pdgfrbtm8Sor | ||||||||||||||||||||||||||||||||||||||
Pdgfrbtm1Sor/Pdgfrbtm9Sor | ||||||||||||||||||||||||||||||||||||||
Pdgfrbtm1Mdt/Pdgfrbtm1Mdt H2az2Tg(Wnt1-cre)11Rth/H2az2+ (conditional) |
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Pdgfrbtm13(Pdgfrb)Sor/Pdgfrb+ Edil3Tg(Sox2-cre)1Amc/Edil3+ (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 07/05/2024 MGI 6.24 |
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