|
Symbol Name ID |
Tnni3
troponin I, cardiac 3 MGI:98783 |
| Darker colors indicate more annotations |
| Human Phenotypes | Cardiomyocyte hypertrophy |
Left atrial enlargement |
Right atrial enlargement |
Ventricular hypertrophy |
Dilated cardiomyopathy |
Hypertrophic cardiomyopathy |
Apical hypertrophic cardiomyopathy |
Interstitial cardiac fibrosis |
Myofiber disarray |
Stroke |
Abnormal left ventricular function |
Severely reduced left ventricular ejection fraction |
Increased left ventricular end-diastolic volume |
Mitral regurgitation |
Tricuspid regurgitation |
Pulmonary venous hypertension |
Supraventricular arrhythmia |
Atrial fibrillation |
Wolff-Parkinson-White syndrome |
Congestive heart failure |
Syncope |
| Disease(s) Associated with TNNI3 | |||||||||||||||||||||
| dilated cardiomyopathy 1FF | |||||||||||||||||||||
| dilated cardiomyopathy 2A | |||||||||||||||||||||
| hypertrophic cardiomyopathy 7 | |||||||||||||||||||||
| restrictive cardiomyopathy |
| Mouse Phenotypes | abnormal lung vasculature morphology |
abnormal myocardium layer morphology |
abnormal myocardial fiber morphology |
abnormal myocardial fiber mitochondrial morphology |
abnormal heart morphology |
dilated heart atrium |
decreased heart weight |
cardiac hypertrophy |
small heart |
abnormal heart ventricle morphology |
cardiac interstitial fibrosis |
abnormal cardiovascular system physiology |
decreased cardiac muscle contractility |
increased cardiac muscle contractility |
decreased cardiac muscle relaxation |
abnormal heart echocardiography feature |
increased left ventricle diastolic pressure |
abnormal myocardial fiber physiology |
increased response of heart to induced stress |
increased systemic arterial diastolic blood pressure |
cardiomyopathy |
congestive heart failure |
|
| Availability | Mouse Genotype | ||||||||||||||||||||||
| Tnni3tm1Jdp/Tnni3tm1Jdp | |||||||||||||||||||||||
| Tnni3tm1Jww/Tnni3tm1Jww | |||||||||||||||||||||||
| Tg(Myh6-Tnni3*L184)#Rste/0 | |||||||||||||||||||||||
| Tg(Myh6-Tnni3*R146G)121Rbns/0 | |||||||||||||||||||||||
| Tg(Myh6-Tnni3*R146G)133Rbns/0 | |||||||||||||||||||||||
| Tg(Myh6-Tnni3*R193H)42Xhu/0 | |||||||||||||||||||||||
| Tg(Myh6-Tnni3*R193H)594Jmme/0 | |||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 07/05/2024 MGI 6.24 |
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