Symbol Name ID |
Gpx1
glutathione peroxidase 1 MGI:104887 |
! | Indicates phenotype varies with strain background. |
Darker colors indicate more annotations |
Human Phenotypes | Increased circulating IgA level |
Increased circulating IgG level |
Decreased circulating antibody level |
Paraproteinemia |
Disease(s) Associated with GPX1 | ||||
multiple myeloma |
Mouse Phenotypes | abnormal cell morphology |
abnormal cell cycle |
decreased cellular sensitivity to gamma-irradiation |
increased cellular sensitivity to oxidative stress |
increased cellular sensitivity to hydrogen peroxide |
increased neuron apoptosis |
cellular necrosis |
decreased cell proliferation |
abnormal mitochondrial physiology |
oxidative stress |
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Availability | Mouse Genotype | ||||||||||
Gpx1tm1Kola/Gpx1tm1Kola | |||||||||||
Gpx1tm1Mgr/Gpx1tm1Mgr | |||||||||||
Gpx1tm1Ysh/Gpx1tm1Ysh | ! |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 07/05/2024 MGI 6.24 |
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