Symbol Name ID |
Brip1
BRCA1 interacting protein C-terminal helicase 1 MGI:2442836 |
Darker colors indicate more annotations |
Human Phenotypes | Increased circulating IgA level |
Increased circulating IgE level |
Chromosomal breakage induced by crosslinking agents |
Disease(s) Associated with BRIP1 | |||
Fanconi anemia complementation group J | |||
thrombocytopenia |
Mouse Phenotypes | oligozoospermia |
abnormal spermatogonia morphology |
decreased primordial germ cell number |
abnormal chromosome morphology |
abnormal cell physiology |
abnormal chiasmata formation |
abnormal X-Y chromosome synapsis during male meiosis |
increased cellular sensitivity to DNA damaging agents |
increased primordial germ cell apoptosis |
decreased primordial germ cell proliferation |
abnormal spermatogonia proliferation |
decreased cell proliferation |
early cellular replicative senescence |
abnormal double-strand DNA break repair |
abnormal DNA replication |
chromosomal instability |
induced chromosome breakage |
|
Availability | Mouse Genotype | |||||||||||||||||
Brip1Gt(RRI409)Byg/Brip1Gt(RRI409)Byg |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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