Symbol Name ID |
Sod2
superoxide dismutase 2, mitochondrial MGI:98352 |
Darker colors indicate more annotations |
Human Phenotypes | Increased circulating IgA level |
Increased circulating IgG level |
Decreased circulating antibody level |
Paraproteinemia |
Intracellular accumulation of autofluorescent lipopigment storage material |
Fingerprint intracellular accumulation of autofluorescent lipopigment storage material |
Disease(s) Associated with SOD2 | ||||||
multiple myeloma | ||||||
neuronal ceroid lipofuscinosis |
Mouse Phenotypes | cardiac interstitial fibrosis |
abnormal mitochondrial crista morphology |
abnormal skeletal muscle fiber mitochondrial morphology |
decreased mitochondrial size |
abnormal cell physiology |
increased cardiomyocyte apoptosis |
increased hepatocyte apoptosis |
abnormal keratinocyte differentiation |
decreased keratinocyte proliferation |
increased muscle cell glucose uptake |
early cellular replicative senescence |
abnormal aerobic respiration |
abnormal tricarboxylic acid cycle |
abnormal respiratory electron transport chain |
abnormal mitochondrial ATP synthesis coupled electron transport |
abnormal mitochondrial physiology |
abnormal oxidative phosphorylation |
oxidative stress |
|
Availability | Mouse Genotype | ||||||||||||||||||
Sod2tm1.1Kskk/Sod2tm1.1Kskk | |||||||||||||||||||
Sod2tm1Cje/Sod2tm1Cje | |||||||||||||||||||
Sod2tm1Leb/Sod2tm1Leb | |||||||||||||||||||
Sod2tm1.1Kskk/Sod2+ | |||||||||||||||||||
Sod2tm1Cje/Sod2+ | |||||||||||||||||||
Sod2tm1Kskk/Sod2tm1Kskk Tg(BEST1-rtTA,tetO-cre)1Yzl/0 (conditional) |
|||||||||||||||||||
Sod2tm1Shs/Sod2tm1Shs Tg(TNNI2-icre)1Vrmn/0 (conditional) |
|||||||||||||||||||
Sod2tm1Shs/Sod2tm1Shs Tg(Cdh16-cre)91Igr/0 (conditional) |
|||||||||||||||||||
Sod2tm1Shs/Sod2tm1Shs Tg(Ckmm-cre)5Khn/0 (conditional) |
|||||||||||||||||||
Sod2tm1Smel/Sod2tm1Smel Tg(KRT14-cre/ERT)20Efu/0 (conditional) |
|||||||||||||||||||
Sod2tm1Shs/Sod2+ Tg(Cdh16-cre)91Igr/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 07/05/2024 MGI 6.24 |
|
|