Symbol Name ID |
Crebbp
CREB binding protein MGI:1098280 |
! | Indicates phenotype varies with strain background. |
Darker colors indicate more annotations |
Human Phenotypes | Abnormality of the hairline |
Low anterior hairline |
Low posterior hairline |
Frontal bossing |
Parietal foramina |
Micrognathia |
Retrognathia |
Hypoplasia of the maxilla |
Large foramen magnum |
Microcephaly |
Delayed cranial suture closure |
Wide anterior fontanel |
Facial grimacing |
Abnormal facial shape |
Facial hemangioma |
Frontal hirsutism |
Prominent forehead |
Smooth philtrum |
Thin upper lip vermilion |
Cleft palate |
High palate |
High, narrow palate |
Narrow palate |
Narrow mouth |
Abnormality of the dentition |
Talon cusp |
Enamel hypoplasia |
Carious teeth |
Dental crowding |
Dental malocclusion |
Increased overbite |
Low hanging columella |
Short columella |
Convex nasal ridge |
Wide nasal bridge |
Deviated nasal septum |
Prominent nose |
Recurrent upper respiratory tract infections |
Broad eyebrow |
Highly arched eyebrow |
Thick eyebrow |
Long eyelashes |
Downslanted palpebral fissures |
Epicanthus |
Telecanthus |
Nasolacrimal duct obstruction |
Disease(s) Associated with CREBBP | ||||||||||||||||||||||||||||||||||||||||||||||
Rubinstein-Taybi syndrome |
Mouse Phenotypes | abnormal craniofacial morphology |
large anterior fontanelle |
wide frontal bone |
abnormal occipital bone morphology |
supernumerary teeth |
short premaxilla |
maxilla hypoplasia |
short maxilla |
nasal bone hypoplasia |
short nasal bone |
cleft secondary palate |
broad nasal bridge |
flattened snout |
short snout |
|
Availability | Mouse Genotype | ||||||||||||||
Crebbptm2Pkb/Crebbptm2Pkb | |||||||||||||||
CrebbpGt(U-San)112Imeg/Crebbp+ | |||||||||||||||
Crebbptm1Dli/Crebbp+ | |||||||||||||||
Crebbptm1Sis/Crebbp+ | ! |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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