Symbol Name ID |
Lrp6
low density lipoprotein receptor-related protein 6 MGI:1298218 |
Darker colors indicate more annotations |
Human Phenotypes | Sparse scalp hair |
Aplasia of the maxilla |
Short face |
Eclabion |
Abnormal dental morphology |
Short dental root |
Taurodontia |
Peg-shaped maxillary lateral incisors |
Abnormal primary molar morphology |
Microdontia |
Agenesis of central incisor |
Agenesis of lateral incisor |
Agenesis of maxillary lateral incisor |
Agenesis of permanent teeth |
Tooth agenesis |
Anodontia |
Hypodontia |
Oligodontia |
Oligodontia of primary teeth |
Selective tooth agenesis |
Agenesis of molar |
Agenesis of permanent molar |
Agenesis of first permanent molar tooth |
Agenesis of premolar |
Agenesis of mandibular premolar |
Abnormality of canine |
Delayed eruption of teeth |
Delayed eruption of permanent teeth |
Enamel hypoplasia |
Hypoplasia of teeth |
Abnormality of primary teeth |
Dental malocclusion |
Widely spaced teeth |
Orofacial cleft |
Impaired mastication |
Sparse eyebrow |
Short eyelashes |
Disease(s) Associated with LRP6 | |||||||||||||||||||||||||||||||||||||
tooth agenesis |
Mouse Phenotypes | abnormal cranium morphology |
small cranium |
abnormal frontal bone morphology |
thin neurocranium |
small lower incisors |
long upper incisors |
short incisors |
abnormal molar cusp morphology |
decreased molar number |
small molars |
abnormal tooth development |
abnormal tooth eruption |
growth retardation of molars |
cleft upper lip |
cleft palate |
protruding tongue |
abnormal nose morphology |
abnormal head shape |
abnormal outer ear morphology |
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Availability | Mouse Genotype | |||||||||||||||||||
Lrp6Cd/Lrp6Cd | ||||||||||||||||||||
Lrp6tm1.2Cjz/Lrp6tm1.2Cjz |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 07/05/2024 MGI 6.24 |
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